FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2609743128> ?p ?o ?g. }

• W2609743128 endingPage "238" @default.
• W2609743128 startingPage "230" @default.
• W2609743128 abstract "Abstract Background The Patient Registry of Intrathecal Ziconotide Management ( PRIZM ) evaluated long‐term effectiveness, safety, and tolerability of intrathecal ziconotide treatment in clinical practice. Methods Patient Registry of Intrathecal Ziconotide Management was an open‐label, long‐term, multicenter, observational study of adult patients with severe chronic pain. This interim analysis (data through July 10, 2015) of ziconotide as the first vs. not first intrathecal agent in pump included change from baseline in the Numeric Pain Rating Scale ( NPRS ; primary efficacy measure) and Patient Global Impression of Change ( PGIC ) scores. Results Enrollment closed at 93 patients; data collection was ongoing at the time of this interim analysis. Fifty‐one patients (54.8%) received ziconotide as the first agent in pump ( FIP +), whereas 42 (45.2%) did not ( FIP −). Mean ( SD ) baseline NPRS scores were 7.4 (1.9) and 7.9 (1.6) in FIP + and FIP − patients, respectively. Mean ( SEM ) percentage changes in NPRS scores were −29.4% (5.5%) in FIP + patients ( n = 26) and +6.4% (7.7%) in FIP − patients ( n = 17) at month 6 and −34.4% (9.1%) in FIP + patients ( n = 14) and −3.4% (10.2%) in FIP − patients ( n = 9) at month 12. Improvement from baseline, measured by PGIC score, was reported in 69.2% of FIP + ( n = 26) and 35.7% of FIP − ( n = 14) patients at month 6 and 85.7% of FIP + ( n = 7) and 71.4% of FIP − ( n = 7) patients at month 12. The most common adverse events (≥ 10% of patients overall as of the data cut) were nausea (19.6% vs. 7.1% of FIP + vs. FIP − patients, respectively), confusional state (9.8% vs. 11.9%), and dizziness (13.7% vs. 7.1%). Conclusions Greater improvements in efficacy outcomes were observed when ziconotide was initiated as first‐line intrathecal therapy vs. not first intrathecal agent in pump. The adverse event profile was consistent with the ziconotide prescribing information." @default.
• W2609743128 created "2017-05-05" @default.
• W2609743128 creator A5005895696 @default.
• W2609743128 creator A5006339040 @default.
• W2609743128 creator A5017547088 @default.
• W2609743128 creator A5023415293 @default.
• W2609743128 creator A5024393802 @default.
• W2609743128 creator A5033859516 @default.
• W2609743128 creator A5034184933 @default.
• W2609743128 creator A5040974260 @default.
• W2609743128 creator A5045020425 @default.
• W2609743128 creator A5051053156 @default.
• W2609743128 date "2017-07-14" @default.
• W2609743128 modified "2023-10-01" @default.
• W2609743128 title "Effectiveness and Safety of Intrathecal Ziconotide: Interim Analysis of the Patient Registry of Intrathecal Ziconotide Management (PRIZM)" @default.
• W2609743128 cites W1594133400 @default.
• W2609743128 cites W1991299462 @default.
• W2609743128 cites W1999893599 @default.
• W2609743128 cites W2071003827 @default.
• W2609743128 cites W2123448847 @default.
• W2609743128 cites W2135923112 @default.
• W2609743128 cites W2151024126 @default.
• W2609743128 cites W2397566167 @default.
• W2609743128 cites W2561558711 @default.
• W2609743128 cites W3136624529 @default.
• W2609743128 cites W5446811 @default.
• W2609743128 doi "https://doi.org/10.1111/papr.12599" @default.
• W2609743128 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28449352" @default.
• W2609743128 hasPublicationYear "2017" @default.
• W2609743128 type Work @default.
• W2609743128 sameAs 2609743128 @default.
• W2609743128 citedByCount "31" @default.
• W2609743128 countsByYear W26097431282018 @default.
• W2609743128 countsByYear W26097431282019 @default.
• W2609743128 countsByYear W26097431282020 @default.
• W2609743128 countsByYear W26097431282021 @default.
• W2609743128 countsByYear W26097431282022 @default.
• W2609743128 countsByYear W26097431282023 @default.
• W2609743128 crossrefType "journal-article" @default.
• W2609743128 hasAuthorship W2609743128A5005895696 @default.
• W2609743128 hasAuthorship W2609743128A5006339040 @default.
• W2609743128 hasAuthorship W2609743128A5017547088 @default.
• W2609743128 hasAuthorship W2609743128A5023415293 @default.
• W2609743128 hasAuthorship W2609743128A5024393802 @default.
• W2609743128 hasAuthorship W2609743128A5033859516 @default.
• W2609743128 hasAuthorship W2609743128A5034184933 @default.
• W2609743128 hasAuthorship W2609743128A5040974260 @default.
• W2609743128 hasAuthorship W2609743128A5045020425 @default.
• W2609743128 hasAuthorship W2609743128A5051053156 @default.
• W2609743128 hasBestOaLocation W26097431281 @default.
• W2609743128 hasConcept C126322002 @default.
• W2609743128 hasConcept C138496976 @default.
• W2609743128 hasConcept C15744967 @default.
• W2609743128 hasConcept C157820659 @default.
• W2609743128 hasConcept C166957645 @default.
• W2609743128 hasConcept C197934379 @default.
• W2609743128 hasConcept C23131810 @default.
• W2609743128 hasConcept C2776957806 @default.
• W2609743128 hasConcept C2778375690 @default.
• W2609743128 hasConcept C42219234 @default.
• W2609743128 hasConcept C535046627 @default.
• W2609743128 hasConcept C61943457 @default.
• W2609743128 hasConcept C71924100 @default.
• W2609743128 hasConcept C83849319 @default.
• W2609743128 hasConcept C95457728 @default.
• W2609743128 hasConceptScore W2609743128C126322002 @default.
• W2609743128 hasConceptScore W2609743128C138496976 @default.
• W2609743128 hasConceptScore W2609743128C15744967 @default.
• W2609743128 hasConceptScore W2609743128C157820659 @default.
• W2609743128 hasConceptScore W2609743128C166957645 @default.
• W2609743128 hasConceptScore W2609743128C197934379 @default.
• W2609743128 hasConceptScore W2609743128C23131810 @default.
• W2609743128 hasConceptScore W2609743128C2776957806 @default.
• W2609743128 hasConceptScore W2609743128C2778375690 @default.
• W2609743128 hasConceptScore W2609743128C42219234 @default.
• W2609743128 hasConceptScore W2609743128C535046627 @default.
• W2609743128 hasConceptScore W2609743128C61943457 @default.
• W2609743128 hasConceptScore W2609743128C71924100 @default.
• W2609743128 hasConceptScore W2609743128C83849319 @default.
• W2609743128 hasConceptScore W2609743128C95457728 @default.
• W2609743128 hasFunder F4320307765 @default.
• W2609743128 hasFunder F4320310567 @default.
• W2609743128 hasFunder F4320332389 @default.
• W2609743128 hasIssue "2" @default.
• W2609743128 hasLocation W26097431281 @default.
• W2609743128 hasLocation W26097431282 @default.
• W2609743128 hasOpenAccess W2609743128 @default.
• W2609743128 hasPrimaryLocation W26097431281 @default.
• W2609743128 hasRelatedWork W1974833954 @default.
• W2609743128 hasRelatedWork W2023402573 @default.
• W2609743128 hasRelatedWork W2084558932 @default.
• W2609743128 hasRelatedWork W2105924009 @default.
• W2609743128 hasRelatedWork W2144554939 @default.
• W2609743128 hasRelatedWork W2224472820 @default.
• W2609743128 hasRelatedWork W2999730687 @default.
• W2609743128 hasRelatedWork W4366605600 @default.
• W2609743128 hasRelatedWork W66630131 @default.
• W2609743128 hasRelatedWork W98011991 @default.

• next