FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2609906631> ?p ?o ?g. }

• W2609906631 endingPage "1762" @default.
• W2609906631 startingPage "1755" @default.
• W2609906631 abstract "BACKGROUND Platelet preparations containing growth factors, attachment factors, and enzymes are appealing to enhance healing of injured tissues and as an alternative to xenogenic serum in cell culture media. Plateletpheresis is commonly used to collect platelets in human medicine but has not been validated in horses. STUDY DESIGN AND METHODS Plateletpheresis to collect platelet concentrate was performed on six female, mixed breed, chemically restrained horses using commercially available apheresis equipment. Before and immediately after plateletpheresis, we performed physical examinations and collected blood for chemistry and coagulation panels and then again at 8, 16, 24, and 48 hours after the procedure. To produce platelet lysate, the platelet concentrate underwent two freeze‐thaw cycles followed by centrifugation and filtration processing. The platelet lysate was then analyzed for cellular debris, fibrinogen, and growth factors. RESULTS The collected platelet concentration contained a mean platelet yield of 390 × 10 3 /μL. Donor platelet count decreased from a mean of 193 × 10 3 /μL to 138 × 10 3 /μL after plateletpheresis, but no individual was at risk for hemorrhage. Pooled platelet lysate had minimal cellular residue and contained growth factor concentrations at 6.1 ng/mL for transforming growth factor‐β1, at 3.5 ng/mL for platelet‐derived growth factor‐BB, and at 13.8 ng/mL for vascular endothelial growth factor‐A. CONCLUSION Plateletpheresis using commercially available apheresis equipment is a feasible option for collecting platelet concentrate from equine donors. The lysate generated from the apheresis product contains growth factors and has potential to be used as a fetal bovine serum substitute for cell culture." @default.
• W2609906631 created "2017-05-05" @default.
• W2609906631 creator A5022558279 @default.
• W2609906631 creator A5024412611 @default.
• W2609906631 creator A5031483945 @default.
• W2609906631 creator A5064378694 @default.
• W2609906631 creator A5070078657 @default.
• W2609906631 date "2017-04-25" @default.
• W2609906631 modified "2023-10-03" @default.
• W2609906631 title "Platelet lysate obtained via plateletpheresis performed in standing and awake equine donors" @default.
• W2609906631 cites W1969583812 @default.
• W2609906631 cites W1970837652 @default.
• W2609906631 cites W1976173563 @default.
• W2609906631 cites W1976427377 @default.
• W2609906631 cites W1980828538 @default.
• W2609906631 cites W1981315552 @default.
• W2609906631 cites W1982666000 @default.
• W2609906631 cites W1984180661 @default.
• W2609906631 cites W1987026155 @default.
• W2609906631 cites W2013036599 @default.
• W2609906631 cites W2014235833 @default.
• W2609906631 cites W2036791701 @default.
• W2609906631 cites W2039713545 @default.
• W2609906631 cites W2044112926 @default.
• W2609906631 cites W2061981400 @default.
• W2609906631 cites W2062493721 @default.
• W2609906631 cites W2078960144 @default.
• W2609906631 cites W2089799650 @default.
• W2609906631 cites W2091128115 @default.
• W2609906631 cites W2096813909 @default.
• W2609906631 cites W2109200717 @default.
• W2609906631 cites W2109587185 @default.
• W2609906631 cites W2113788262 @default.
• W2609906631 cites W2137242127 @default.
• W2609906631 cites W2144093008 @default.
• W2609906631 cites W2156905839 @default.
• W2609906631 cites W2167741353 @default.
• W2609906631 cites W2213727944 @default.
• W2609906631 cites W4322695620 @default.
• W2609906631 doi "https://doi.org/10.1111/trf.14124" @default.
• W2609906631 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28439897" @default.
• W2609906631 hasPublicationYear "2017" @default.
• W2609906631 type Work @default.
• W2609906631 sameAs 2609906631 @default.
• W2609906631 citedByCount "16" @default.
• W2609906631 countsByYear W26099066312018 @default.
• W2609906631 countsByYear W26099066312019 @default.
• W2609906631 countsByYear W26099066312020 @default.
• W2609906631 countsByYear W26099066312021 @default.
• W2609906631 countsByYear W26099066312022 @default.
• W2609906631 countsByYear W26099066312023 @default.
• W2609906631 crossrefType "journal-article" @default.
• W2609906631 hasAuthorship W2609906631A5022558279 @default.
• W2609906631 hasAuthorship W2609906631A5024412611 @default.
• W2609906631 hasAuthorship W2609906631A5031483945 @default.
• W2609906631 hasAuthorship W2609906631A5064378694 @default.
• W2609906631 hasAuthorship W2609906631A5070078657 @default.
• W2609906631 hasBestOaLocation W26099066311 @default.
• W2609906631 hasConcept C1621761 @default.
• W2609906631 hasConcept C16685009 @default.
• W2609906631 hasConcept C203014093 @default.
• W2609906631 hasConcept C2776662772 @default.
• W2609906631 hasConcept C2776738589 @default.
• W2609906631 hasConcept C2779867487 @default.
• W2609906631 hasConcept C2908955001 @default.
• W2609906631 hasConcept C3018697912 @default.
• W2609906631 hasConcept C57409179 @default.
• W2609906631 hasConcept C71924100 @default.
• W2609906631 hasConcept C89560881 @default.
• W2609906631 hasConceptScore W2609906631C1621761 @default.
• W2609906631 hasConceptScore W2609906631C16685009 @default.
• W2609906631 hasConceptScore W2609906631C203014093 @default.
• W2609906631 hasConceptScore W2609906631C2776662772 @default.
• W2609906631 hasConceptScore W2609906631C2776738589 @default.
• W2609906631 hasConceptScore W2609906631C2779867487 @default.
• W2609906631 hasConceptScore W2609906631C2908955001 @default.
• W2609906631 hasConceptScore W2609906631C3018697912 @default.
• W2609906631 hasConceptScore W2609906631C57409179 @default.
• W2609906631 hasConceptScore W2609906631C71924100 @default.
• W2609906631 hasConceptScore W2609906631C89560881 @default.
• W2609906631 hasIssue "7" @default.
• W2609906631 hasLocation W26099066311 @default.
• W2609906631 hasLocation W26099066312 @default.
• W2609906631 hasOpenAccess W2609906631 @default.
• W2609906631 hasPrimaryLocation W26099066311 @default.
• W2609906631 hasRelatedWork W1964714411 @default.
• W2609906631 hasRelatedWork W2061749223 @default.
• W2609906631 hasRelatedWork W2100269967 @default.
• W2609906631 hasRelatedWork W2154253381 @default.
• W2609906631 hasRelatedWork W2385542649 @default.
• W2609906631 hasRelatedWork W2610770224 @default.
• W2609906631 hasRelatedWork W2758703992 @default.
• W2609906631 hasRelatedWork W2884273145 @default.
• W2609906631 hasRelatedWork W4242679087 @default.
• W2609906631 hasRelatedWork W789821843 @default.
• W2609906631 hasVolume "57" @default.
• W2609906631 isParatext "false" @default.
• W2609906631 isRetracted "false" @default.

• next