Matches in SemOpenAlex for { <https://semopenalex.org/work/W2609960419> ?p ?o ?g. }
- W2609960419 endingPage "1389" @default.
- W2609960419 startingPage "1378" @default.
- W2609960419 abstract "We investigated the genetic background and microbiological features of T6SS-positive Acinetobacter baumannii isolates and clinical impact of the T6SS in patients with A. baumannii bacteremia. One hundred and 62 A. baumannii isolates from patients with bacteremia in 2 tertiary-care hospitals in Korea were included in this study. Approximately one-third (51/162, 31.5%) of the A. baumannii clinical isolates possessed the hcp gene, and the hcp-positive isolates were found in several genotypes in multilocus sequence typing. The expression and secretion of Hcp protein varied among the clinical isolates. A. baumannii isolates with detectable Hcp secretion (T6SS+) could better outcompete Escherichia coli compared with T6SS- isolates, including hcp-negative and inactivated hcp-positive isolates. In addition, T6SS+ isolates showed higher biofilm-forming activity and better survival in the presence of normal human serum than the T6SS- isolates. T6SS+ isolates were more frequently detected in patients with catheter-related bloodstream infection, haematopoietic stem cell transplant recipients, and patients receiving immunosuppressive agents. However, T6SS was not a prognostic factor for mortality. Our results suggest that the T6SS of A. baumannii is associated with virulence and contributes to infections in immunocompromised patients and those with implanted medical devices." @default.
- W2609960419 created "2017-05-05" @default.
- W2609960419 creator A5018893019 @default.
- W2609960419 creator A5031056182 @default.
- W2609960419 creator A5032173154 @default.
- W2609960419 creator A5060559119 @default.
- W2609960419 creator A5066419377 @default.
- W2609960419 creator A5074327369 @default.
- W2609960419 creator A5080891156 @default.
- W2609960419 creator A5086462781 @default.
- W2609960419 date "2017-05-19" @default.
- W2609960419 modified "2023-10-17" @default.
- W2609960419 title "Microbiological features and clinical impact of the type VI secretion system (T6SS) in <i>Acinetobacter baumannii</i> isolates causing bacteremia" @default.
- W2609960419 cites W1742951822 @default.
- W2609960419 cites W1967300023 @default.
- W2609960419 cites W1970786682 @default.
- W2609960419 cites W1972038449 @default.
- W2609960419 cites W1976555793 @default.
- W2609960419 cites W1978441703 @default.
- W2609960419 cites W1986130209 @default.
- W2609960419 cites W1987732066 @default.
- W2609960419 cites W2014526984 @default.
- W2609960419 cites W2026650809 @default.
- W2609960419 cites W2032892508 @default.
- W2609960419 cites W2036456340 @default.
- W2609960419 cites W2038414721 @default.
- W2609960419 cites W2061796105 @default.
- W2609960419 cites W2064483810 @default.
- W2609960419 cites W2065235521 @default.
- W2609960419 cites W2080001285 @default.
- W2609960419 cites W2081918703 @default.
- W2609960419 cites W2087928701 @default.
- W2609960419 cites W2094643746 @default.
- W2609960419 cites W2096488671 @default.
- W2609960419 cites W2097700470 @default.
- W2609960419 cites W2107576972 @default.
- W2609960419 cites W2108920131 @default.
- W2609960419 cites W2112459888 @default.
- W2609960419 cites W2115584178 @default.
- W2609960419 cites W2115704819 @default.
- W2609960419 cites W2115806935 @default.
- W2609960419 cites W2119683190 @default.
- W2609960419 cites W2121383808 @default.
- W2609960419 cites W2122095711 @default.
- W2609960419 cites W2125832470 @default.
- W2609960419 cites W2127438500 @default.
- W2609960419 cites W2128561534 @default.
- W2609960419 cites W2133394828 @default.
- W2609960419 cites W2137087452 @default.
- W2609960419 cites W2138779519 @default.
- W2609960419 cites W2141436268 @default.
- W2609960419 cites W2142343447 @default.
- W2609960419 cites W2162539493 @default.
- W2609960419 cites W2168895472 @default.
- W2609960419 cites W2260630395 @default.
- W2609960419 cites W2296123365 @default.
- W2609960419 cites W2298135825 @default.
- W2609960419 cites W2413389794 @default.
- W2609960419 cites W2488719483 @default.
- W2609960419 cites W2613483874 @default.
- W2609960419 doi "https://doi.org/10.1080/21505594.2017.1323164" @default.
- W2609960419 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5711433" @default.
- W2609960419 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28448786" @default.
- W2609960419 hasPublicationYear "2017" @default.
- W2609960419 type Work @default.
- W2609960419 sameAs 2609960419 @default.
- W2609960419 citedByCount "41" @default.
- W2609960419 countsByYear W26099604192017 @default.
- W2609960419 countsByYear W26099604192018 @default.
- W2609960419 countsByYear W26099604192019 @default.
- W2609960419 countsByYear W26099604192020 @default.
- W2609960419 countsByYear W26099604192021 @default.
- W2609960419 countsByYear W26099604192022 @default.
- W2609960419 countsByYear W26099604192023 @default.
- W2609960419 crossrefType "journal-article" @default.
- W2609960419 hasAuthorship W2609960419A5018893019 @default.
- W2609960419 hasAuthorship W2609960419A5031056182 @default.
- W2609960419 hasAuthorship W2609960419A5032173154 @default.
- W2609960419 hasAuthorship W2609960419A5060559119 @default.
- W2609960419 hasAuthorship W2609960419A5066419377 @default.
- W2609960419 hasAuthorship W2609960419A5074327369 @default.
- W2609960419 hasAuthorship W2609960419A5080891156 @default.
- W2609960419 hasAuthorship W2609960419A5086462781 @default.
- W2609960419 hasBestOaLocation W26099604191 @default.
- W2609960419 hasConcept C104317684 @default.
- W2609960419 hasConcept C135763542 @default.
- W2609960419 hasConcept C2776315533 @default.
- W2609960419 hasConcept C2777637488 @default.
- W2609960419 hasConcept C2779443120 @default.
- W2609960419 hasConcept C501593827 @default.
- W2609960419 hasConcept C523546767 @default.
- W2609960419 hasConcept C54355233 @default.
- W2609960419 hasConcept C60987743 @default.
- W2609960419 hasConcept C77434933 @default.
- W2609960419 hasConcept C86803240 @default.
- W2609960419 hasConcept C89423630 @default.
- W2609960419 hasConceptScore W2609960419C104317684 @default.
- W2609960419 hasConceptScore W2609960419C135763542 @default.