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• W2610049780 endingPage "e3291" @default.
• W2610049780 startingPage "e3291" @default.
• W2610049780 abstract "Symbiotic bacteria are common in insects and can affect various aspects of their hosts’ biology. Although the effects of insect symbionts have been clarified for various insect symbiosis models, due to the difficulty of cultivating them in vitro , there is still limited knowledge available on the molecular features that drive symbiosis. Serratia symbiotica is one of the most common symbionts found in aphids. The recent findings of free-living strains that are considered as nascent partners of aphids provide the opportunity to examine the molecular mechanisms that a symbiont can deploy at the early stages of the symbiosis (i.e., symbiotic factors). In this work, a proteomic approach was used to establish a comprehensive proteome map of the free-living S. symbiotica strain CWBI-2.3 T . Most of the 720 proteins identified are related to housekeeping or primary metabolism. Of these, 76 were identified as candidate proteins possibly promoting host colonization. Our results provide strong evidence that S. symbiotica CWBI-2.3 T is well-armed for invading insect host tissues, and suggest that certain molecular features usually harbored by pathogenic bacteria are no longer present. This comprehensive proteome map provides a series of candidate genes for further studies to understand the molecular cross-talk between insects and symbiotic bacteria." @default.
• W2610049780 created "2017-05-05" @default.
• W2610049780 creator A5013787276 @default.
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• W2610049780 creator A5056973679 @default.
• W2610049780 creator A5058261651 @default.
• W2610049780 creator A5091061344 @default.
• W2610049780 date "2017-05-09" @default.
• W2610049780 modified "2023-10-11" @default.
• W2610049780 title "Toward a better understanding of the mechanisms of symbiosis: a comprehensive proteome map of a nascent insect symbiont" @default.
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