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• W2610107585 abstract "Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation. The presence of autoantibodies in the sera of RA patients has provided many clues to the underlying disease pathophysiology. Based on the presence of several autoantibodies like rheumatoid factor (RF), anti-citrullinated protein antibodies (ACPA), anti-carbamylated protein antibodies (anti-CarP), and more recently anti-acetylated protein antibodies RA can be subdivided into seropositive and seronegative disease. The formation of these autoantibodies is associated with both genetic and environmental risk factors for RA, like specific human leukocyte antigen (HLA) alleles and smoking. Autoantibodies can be detected many years before disease onset in a subset of patients, suggesting a sequence of events in which the first autoantibodies develop in predisposed hosts, before an inflammatory response ensues leading to clinically apparent arthritis. Research on the characteristics and effector functions of these autoantibodies might provide more insight in pathophysiological processes underlying arthritis in RA. Recent data suggests that ACPA might play a role in perpetuating inflammation once it has developed. Furthermore, pathophysiological mechanisms have been discovered supporting a direct link between the presence of ACPA and both bone erosions and pain in RA patients. In conclusion, investigating the possible pathogenic potential of autoantibodies might lead to improved understanding of the underlying pathophysiological processes in rheumatoid arthritis." @default.
• W2610107585 created "2017-05-05" @default.
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• W2610107585 date "2017-04-27" @default.
• W2610107585 modified "2023-10-02" @default.
• W2610107585 title "The role of autoantibodies in the pathophysiology of rheumatoid arthritis" @default.
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• W2610107585 cites W1751722025 @default.
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• W2610107585 cites W1947692427 @default.
• W2610107585 cites W1964890547 @default.
• W2610107585 cites W1974718865 @default.
• W2610107585 cites W1980024538 @default.
• W2610107585 cites W1994402720 @default.
• W2610107585 cites W2006547485 @default.
• W2610107585 cites W2012139859 @default.
• W2610107585 cites W2013573826 @default.
• W2610107585 cites W2015865604 @default.
• W2610107585 cites W2016382347 @default.
• W2610107585 cites W2019472897 @default.
• W2610107585 cites W2019582534 @default.
• W2610107585 cites W2024988150 @default.
• W2610107585 cites W2025408360 @default.
• W2610107585 cites W2031823694 @default.
• W2610107585 cites W2040474392 @default.
• W2610107585 cites W2059353973 @default.
• W2610107585 cites W2062566352 @default.
• W2610107585 cites W2064349379 @default.
• W2610107585 cites W2073363749 @default.
• W2610107585 cites W2079026023 @default.
• W2610107585 cites W2082991836 @default.
• W2610107585 cites W2085192554 @default.
• W2610107585 cites W2093114687 @default.
• W2610107585 cites W2093120748 @default.
• W2610107585 cites W2096966555 @default.
• W2610107585 cites W2101647626 @default.
• W2610107585 cites W2103991421 @default.
• W2610107585 cites W2107005433 @default.
• W2610107585 cites W2109578241 @default.
• W2610107585 cites W2110826367 @default.
• W2610107585 cites W2113071099 @default.
• W2610107585 cites W2113552312 @default.
• W2610107585 cites W2113832500 @default.
• W2610107585 cites W2115694552 @default.
• W2610107585 cites W2118418739 @default.
• W2610107585 cites W2119716615 @default.
• W2610107585 cites W2122176733 @default.
• W2610107585 cites W2122507029 @default.
• W2610107585 cites W2124197653 @default.
• W2610107585 cites W2134293530 @default.
• W2610107585 cites W2136131602 @default.
• W2610107585 cites W2141522272 @default.
• W2610107585 cites W2142396487 @default.
• W2610107585 cites W2142544801 @default.
• W2610107585 cites W2146707828 @default.
• W2610107585 cites W2150663819 @default.
• W2610107585 cites W2152818840 @default.
• W2610107585 cites W2153524721 @default.
• W2610107585 cites W2162387133 @default.
• W2610107585 cites W2164744416 @default.
• W2610107585 cites W2167131572 @default.
• W2610107585 cites W2177851274 @default.
• W2610107585 cites W2180347427 @default.
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• W2610107585 cites W2322214491 @default.
• W2610107585 cites W2337881360 @default.
• W2610107585 cites W2344788791 @default.
• W2610107585 cites W2344839616 @default.
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• W2610107585 cites W2562800512 @default.
• W2610107585 cites W2566549007 @default.
• W2610107585 cites W2586257347 @default.
• W2610107585 cites W2589710212 @default.
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• W2610107585 doi "https://doi.org/10.1007/s00281-017-0627-z" @default.
• W2610107585 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5486798" @default.
• W2610107585 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28451788" @default.
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