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- W2610210647 abstract "Maturation of metabolomics has brought a deeper appreciation for the importance of isomeric identity of lipids to their biological role, mirroring that for proteoforms in proteomics. However, full characterization of the lipid isomerism has been thwarted by paucity of rapid and effective analytical tools. A novel approach is ion mobility spectrometry (IMS) and particularly differential or field asymmetric waveform IMS (FAIMS) at high electric fields, which is more orthogonal to mass spectrometry. Here we broadly explore the power of FAIMS to separate lipid isomers, and find a ~75% success rate across the four major types of glycero- and phospho- lipids (sn, chain length, double bond position, and cis/trans). The resolved isomers were identified using standards, and (for the first two types) tandem mass spectrometry. These results demonstrate the general merit of incorporating high-resolution FAIMS into lipidomic analyses. Graphical Abstract ᅟ." @default.
- W2610210647 created "2017-05-12" @default.
- W2610210647 creator A5013320088 @default.
- W2610210647 creator A5029979758 @default.
- W2610210647 creator A5077165139 @default.
- W2610210647 date "2017-05-01" @default.
- W2610210647 modified "2023-10-01" @default.
- W2610210647 title "Broad Separation of Isomeric Lipids by High-Resolution Differential Ion Mobility Spectrometry with Tandem Mass Spectrometry" @default.
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- W2610210647 cites W1549988612 @default.
- W2610210647 cites W1840351579 @default.
- W2610210647 cites W1959992677 @default.
- W2610210647 cites W1965315089 @default.
- W2610210647 cites W1968518360 @default.
- W2610210647 cites W1971097535 @default.
- W2610210647 cites W1974203321 @default.
- W2610210647 cites W1978235493 @default.
- W2610210647 cites W1978424825 @default.
- W2610210647 cites W1983012121 @default.
- W2610210647 cites W1986002042 @default.
- W2610210647 cites W1991033357 @default.
- W2610210647 cites W1994869822 @default.
- W2610210647 cites W1994914961 @default.
- W2610210647 cites W1996797462 @default.
- W2610210647 cites W1998161543 @default.
- W2610210647 cites W2001306509 @default.
- W2610210647 cites W2002579997 @default.
- W2610210647 cites W2002687705 @default.
- W2610210647 cites W2004574784 @default.
- W2610210647 cites W2009795328 @default.
- W2610210647 cites W2011616239 @default.
- W2610210647 cites W2016952132 @default.
- W2610210647 cites W2031520719 @default.
- W2610210647 cites W2035133786 @default.
- W2610210647 cites W2045950965 @default.
- W2610210647 cites W2046163243 @default.
- W2610210647 cites W2046778552 @default.
- W2610210647 cites W2049796168 @default.
- W2610210647 cites W2050110509 @default.
- W2610210647 cites W2061733910 @default.
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- W2610210647 cites W2077750625 @default.
- W2610210647 cites W2078394205 @default.
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- W2610210647 doi "https://doi.org/10.1007/s13361-017-1675-2" @default.
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