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• W2610363069 abstract "Abstract Little is known about concurrent infection with hepatitis C virus (HCV) and Streptococcus pneumoniae, which causes invasive pneumococcal disease (IPD). We hypothesized that co-infection with HCV and S. pneumoniae would increase risk for death and complications. We captured sociodemographic and serologic data for adults with IPD in a population-based cohort study in northern Alberta, Canada, during 2000–2014. IPD patients infected with HCV were compared with IPD patients not infected with HCV for risk of in-hospital deaths and complications by using multivariable logistic regression. A total of 355 of 3,251 patients with IPD were co-infected with HCV. The in-hospital mortality rate was higher for IPD patients infected with HCV. Prevalence of most IPD-related complications (e.g., cellulitis, acute kidney injury, mechanical ventilation) was also higher in HCV-infected patients. Infection with HCV is common in patients with IPD, and HCV is independently associated with an increased risk for serious illness and death." @default.
• W2610363069 created "2017-05-12" @default.
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• W2610363069 date "2017-07-01" @default.
• W2610363069 modified "2023-09-27" @default.
• W2610363069 title "Concurrent Infection with Hepatitis C Virus and<i>Streptococcus pneumoniae</i>" @default.
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• W2610363069 doi "https://doi.org/10.3201/eid2307.161858" @default.
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