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- W2610391635 endingPage "356" @default.
- W2610391635 startingPage "339" @default.
- W2610391635 abstract "Extra-uterine high-grade serous carcinoma (HGSC) accounts for most of the morbidity and mortality associated with ovarian carcinoma, and is one of the leading causes of cancer death in women. Until recently our understanding of HGSC was very limited compared to other common cancers, and it has only been during the last 15 years that we have learned how to diagnose this ovarian carcinoma histotype accurately. Since then, however, there has been rapid progress, with identification of a precursor lesion in the fallopian tube, development of prevention strategies for both those with inherited susceptibility (hereditary breast and ovarian cancer syndrome) and without the syndrome, and elucidation of the molecular events important in oncogenesis. This molecular understanding has led to new treatment strategies for HGSC, with the promise of more to come in the near future. In this review we focus on these recent changes, including diagnostic criteria/differential diagnosis, primary site assignment, precursor lesions and the molecular pathology of HGSC." @default.
- W2610391635 created "2017-05-12" @default.
- W2610391635 creator A5008725360 @default.
- W2610391635 creator A5032474916 @default.
- W2610391635 creator A5084183460 @default.
- W2610391635 date "2017-07-18" @default.
- W2610391635 modified "2023-10-14" @default.
- W2610391635 title "High-grade serous carcinoma of tubo-ovarian origin: recent developments" @default.
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