Matches in SemOpenAlex for { <https://semopenalex.org/work/W2611033623> ?p ?o ?g. }
- W2611033623 endingPage "101042831769757" @default.
- W2611033623 startingPage "101042831769757" @default.
- W2611033623 abstract "We aimed to investigate the prognostic value of the immune cells population in peripheral blood from patients with advanced gastric cancer treated with neoadjuvant chemotherapy. A total of 105 patients with advanced gastric cancer were evaluated in this study. Blood samples were collected before and 1 week after the last dose of chemotherapy. The percentage of CD3+, CD3+CD4+, CD3+CD8+, and CD4+CD25+Foxp3+ T cells was assessed using flow cytometry analysis. The relationship between T cell subsets and clinical outcome was evaluated. The percentage of CD3+CD8+ lymphocytes was significantly increased after chemotherapy and CD4+CD25+Foxp3+ regulatory T cells (Tregs) decreased ( p = 0.003 and p < 0.001, respectively). The percentage of CD3+CD8+ lymphocytes and Tregs was strongly associated with response to chemotherapy ( p = 0.017 and p < 0.030, respectively). Patients with high CD3+CD8+ T cells and low CD4+CD25+Foxp3+ Tregs had significantly increased overall survival ( p = 0.012 and p = 0.048, respectively). Neither CD3+ nor CD3+CD4+ T cells showed significant changes after chemotherapy or correlations with the clinical outcome. The positive correlation between a high CD3+CD8+ T cells or low CD4+CD25+Foxp3+ Tregs and clinical outcome indicates its key role in the prognosis of gastric cancer patients and may serve as a biomarker to identify patients likely to benefit from neoadjuvant chemotherapy." @default.
- W2611033623 created "2017-05-12" @default.
- W2611033623 creator A5025756253 @default.
- W2611033623 creator A5026107379 @default.
- W2611033623 creator A5027066998 @default.
- W2611033623 creator A5040934642 @default.
- W2611033623 creator A5070375135 @default.
- W2611033623 creator A5071709424 @default.
- W2611033623 creator A5088278644 @default.
- W2611033623 date "2017-05-01" @default.
- W2611033623 modified "2023-10-13" @default.
- W2611033623 title "Impact of the immune cell population in peripheral blood on response and survival in patients receiving neoadjuvant chemotherapy for advanced gastric cancer" @default.
- W2611033623 cites W1574992033 @default.
- W2611033623 cites W1631276405 @default.
- W2611033623 cites W1977093042 @default.
- W2611033623 cites W1984976313 @default.
- W2611033623 cites W2011627030 @default.
- W2611033623 cites W2016612145 @default.
- W2611033623 cites W2017999136 @default.
- W2611033623 cites W2029695719 @default.
- W2611033623 cites W2033917892 @default.
- W2611033623 cites W2047902191 @default.
- W2611033623 cites W2052329251 @default.
- W2611033623 cites W2053829861 @default.
- W2611033623 cites W2068155679 @default.
- W2611033623 cites W2073083233 @default.
- W2611033623 cites W2083991703 @default.
- W2611033623 cites W2088765739 @default.
- W2611033623 cites W2103351853 @default.
- W2611033623 cites W2105459360 @default.
- W2611033623 cites W2111585885 @default.
- W2611033623 cites W2113947048 @default.
- W2611033623 cites W2115072149 @default.
- W2611033623 cites W2117115065 @default.
- W2611033623 cites W2141269240 @default.
- W2611033623 cites W2146470803 @default.
- W2611033623 cites W2150678612 @default.
- W2611033623 cites W2168069492 @default.
- W2611033623 cites W2170240868 @default.
- W2611033623 cites W2212189494 @default.
- W2611033623 cites W2296492322 @default.
- W2611033623 cites W2343205340 @default.
- W2611033623 cites W2406984136 @default.
- W2611033623 doi "https://doi.org/10.1177/1010428317697571" @default.
- W2611033623 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28475005" @default.
- W2611033623 hasPublicationYear "2017" @default.
- W2611033623 type Work @default.
- W2611033623 sameAs 2611033623 @default.
- W2611033623 citedByCount "11" @default.
- W2611033623 countsByYear W26110336232018 @default.
- W2611033623 countsByYear W26110336232019 @default.
- W2611033623 countsByYear W26110336232020 @default.
- W2611033623 countsByYear W26110336232021 @default.
- W2611033623 countsByYear W26110336232022 @default.
- W2611033623 countsByYear W26110336232023 @default.
- W2611033623 crossrefType "journal-article" @default.
- W2611033623 hasAuthorship W2611033623A5025756253 @default.
- W2611033623 hasAuthorship W2611033623A5026107379 @default.
- W2611033623 hasAuthorship W2611033623A5027066998 @default.
- W2611033623 hasAuthorship W2611033623A5040934642 @default.
- W2611033623 hasAuthorship W2611033623A5070375135 @default.
- W2611033623 hasAuthorship W2611033623A5071709424 @default.
- W2611033623 hasAuthorship W2611033623A5088278644 @default.
- W2611033623 hasBestOaLocation W26110336231 @default.
- W2611033623 hasConcept C114684123 @default.
- W2611033623 hasConcept C121608353 @default.
- W2611033623 hasConcept C126322002 @default.
- W2611033623 hasConcept C143998085 @default.
- W2611033623 hasConcept C167672396 @default.
- W2611033623 hasConcept C203014093 @default.
- W2611033623 hasConcept C2776090121 @default.
- W2611033623 hasConcept C2776694085 @default.
- W2611033623 hasConcept C2778296632 @default.
- W2611033623 hasConcept C2779727006 @default.
- W2611033623 hasConcept C2908647359 @default.
- W2611033623 hasConcept C71924100 @default.
- W2611033623 hasConcept C79484868 @default.
- W2611033623 hasConcept C8891405 @default.
- W2611033623 hasConcept C90924648 @default.
- W2611033623 hasConcept C99454951 @default.
- W2611033623 hasConceptScore W2611033623C114684123 @default.
- W2611033623 hasConceptScore W2611033623C121608353 @default.
- W2611033623 hasConceptScore W2611033623C126322002 @default.
- W2611033623 hasConceptScore W2611033623C143998085 @default.
- W2611033623 hasConceptScore W2611033623C167672396 @default.
- W2611033623 hasConceptScore W2611033623C203014093 @default.
- W2611033623 hasConceptScore W2611033623C2776090121 @default.
- W2611033623 hasConceptScore W2611033623C2776694085 @default.
- W2611033623 hasConceptScore W2611033623C2778296632 @default.
- W2611033623 hasConceptScore W2611033623C2779727006 @default.
- W2611033623 hasConceptScore W2611033623C2908647359 @default.
- W2611033623 hasConceptScore W2611033623C71924100 @default.
- W2611033623 hasConceptScore W2611033623C79484868 @default.
- W2611033623 hasConceptScore W2611033623C8891405 @default.
- W2611033623 hasConceptScore W2611033623C90924648 @default.
- W2611033623 hasConceptScore W2611033623C99454951 @default.
- W2611033623 hasIssue "5" @default.
- W2611033623 hasLocation W26110336231 @default.