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- W2611034844 abstract "This is a report of 3 studies. In the 1st weekly intramuscular or oral doses of 500 mg to 1 gm of medroxyprogesterone acetate (Provera) were given for 4 weeks to patients with primary adenocarcinoma confined to the uterus. Subsequent radium therapy was given. Residual cancer tissue was found in only 1/3 of the pretreated patients while in a similar group not pretreated residual cancer tissue was found in almost all. In another study of recurrent cases with metastases medroxyprogesterone acetate was the only treatment used for 10 weeks. Marked regression was noted in 1/3 of these cases. Another 1/3 showed some slowing of the tumor growth. Telecobalt therapy for those patients not responding to the hormone therapy caused tumor recession in some. A single instillation of medroxyprogesterone acetate into the uterus produced similar histological changes in the endometrium as those produced by the oral or intramuscular therapy. Adenocarcinomas originating in the cervix or corpus uteri were equally susceptible to medroxyprogesterone acetate therapy." @default.
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- W2611034844 date "1967-01-01" @default.
- W2611034844 modified "2023-09-24" @default.
- W2611034844 title "Treatment of adenocarcinomas of the uterus with medroxyprogesterone. (Abstract only)" @default.
- W2611034844 hasPublicationYear "1967" @default.
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