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- W2611113072 abstract "Objective: To determine diagnostic accuracy of gray-scale and colour doppler ultrasonography in diagnosing malignant thyroid nodules.Study Design: Validation study.Place and Duration of Study: Radiology department Combined Military Hospital (CMH) and Military Hospital (MH) Rawalpindi from July 2007 to July 2008.Subjects and Methods: Fifty cases of solitary/multinodular goitre with clinical suspicion of malignancy were included in the study by non-probability purposive sampling. Gray-scale and colour doppler ultrasonography of neck/thyroid gland was done and results were compared with histo-pathological findings from Armed Forces Institute of Pathology (AFIP) and Army Medical College keeping histopathology as gold standard.Results: In 50 patients, 10 cases found to have ultrasound findings suspicious of malignancy. Out of these 10 cases, 6 cases confirmed as malignant on histopathology. In 40 patients with benign ultrasound findings, one had malignancy on histo-pathological examination. Out of these 7 patients with confirmed malignancy, four had papillary carcinoma; two had follicular carcinomas and one anaplastic carcinoma. Diagnostic parameters calculated and found to be: sensitivity 85.7%; specificity 90.6%; PPV 60%; NPP 97.5% and accuracy of 90%. Conclusion: Gray-scale and colour doppler ultrasonography is a good technique in diagnosing malignant thyroid nodules. Entirely solid nodule with no cystic element having spiculated margins, micro-calcifications and central flow are helpful sonographic findings pointing towards malignancy. Associated cervical lymphadenopathy with calcification or degeneration is a significant finding favouring malignancy." @default.
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- W2611113072 date "2016-08-31" @default.
- W2611113072 modified "2023-09-23" @default.
- W2611113072 title "DIAGNOSTIC ACCURACY OF GRAY-SCALE AND COLOUR DOPPLER ULTRASONOGRAPHY IN DIAGNOSING MALIGNANT THYROID NODULES" @default.
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