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- W2611150435 abstract "Bevezetes: A terapias besugarzas es a kulonboző kemoterapias szerek karosithatjak a tudőt. Celkitűzes: Jelen tanulmany celja a gyermekkori daganatellenes kezelesben reszesultek utankovetese, a pulmonalis toxicitas lefolyasanak monitorozasa volt. Betegek es modszerek: A vizsgalatban 26 szemely (10 leany es 16 fiu) vett reszt, atlageletkoruk 19,4 ev volt, a kezelestől az első felmeresig eltelt atlagos idő 4,5 ev, a masodik felmeresig eltelt atlagos idő 10 ev volt. Eredmenyek: 14 esetben eszleltek koros legzesfunkcios eredmenyt az első felmeres alkalmaval, ebből het obstruktiv, ot kevert, kettő pedig restriktiv jellegű zavar volt. A masodik felmeres soran a koros esetek szama hatra csokkent, akik kozul ket esetben obstruktiv es negy esetben restriktiv jellegű elterest tapasztaltak. A dinamikus parameterek pozitiv iranyu valtozasa minden koros ertekben nyomon kovethető volt (p<0,05). A statikus parameterek ertekelese soran szinten javulasi tendenciat figyeltek meg, azonban ez nem mutatott szignifikans merteket. Kovetkeztetes: Restriktiv jellegű legzeszavar a kezeltek kis reszeben mutathato ki. A kezeles kovetkezteben fellepő pulmonalis obstruktiv elvaltozasok az idő előrehaladtaval javulo tendenciat mutatnak. Orv. Hetil., 2013, 154, 345–350. | Introduction: The present investigation was based on a survey in 2005, in which the authors found pulmonary function abnormalities in survivors of childhood cancer, who were treated with anticancer therapy. Aim: The purpose of the present study was to follow-up childhood cancer survivors and detect late pulmonary toxicity. Patients and methods: Lung function test was performed with spirometry in 26 survivors participated in this study (10 females and 16 males; mean age, 19.4 years at the time of the second follow-up evaluation). The average time periods from treatment until the first and second follow-up evaluation were 4.5 and 10 years, respectively. Results: The authors found 14 patients with pathological pulmonary function tests results at the time of the first follow-up evaluation, from which 7 patients had obstructive, 5 patients had mixed and 2 patients had restrictive abnormalities. However, there were only 6 patients who had abnormal pulmonary function at the time of the second follow-up evaluation (2 patients with obstructive and 4 patients with restrictive pulmonary function tests (p<0.05). Conclusion: Restrictive pulmonary disorder was detected in only small part of the treated patients. The obsructive pulmonary abnormalities caused by the treatment showed an improving tendency over time. Orv. Hetil., 2013, 154, 345–350." @default.
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- W2611150435 date "2013-01-01" @default.
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- W2611150435 title "Daganatellenes kezelésben részesült gyermekek késői pulmonalis toxicitásának vizsgálata | Examination of late pulmonary toxicity in children treated for malignancies" @default.
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