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• W2611190100 abstract "The high stability and functional group compatibility of ruthenium carbene complexes confer them a great ability to catalyze domino processes. For this reason, the combination of metathesis reactions with additional transformations in a domino fashion has been exploited extensively, with the result of expanding the utility of ruthenium carbene complexes beyond that of just olefin metathesis. Among those domino processes, it is worth mentioning the sequence of cross-metathesis/intramolecular Michael addition, which allows for the generation of a wide variety of carbo- and heterocycles in a very simple manner, taking advantage of the benefits of domino reactions. Carbon-, oxygen- and nitrogen-centered nucleophiles are good partners in this protocol, the versatility of which has been illustrated with the synthesis of several biologically important compounds. 1 Introduction 2 Cross Metathesis/Intramolecular Aza-Michael Addition Sequences 3 Cross Metathesis/Intramolecular Oxa-Michael Addition Sequences 4 Cross Metathesis/Intramolecular Michael Addition Sequences 5 Conclusions and Outlook" @default.
• W2611190100 created "2017-05-12" @default.
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• W2611190100 date "2017-05-04" @default.
• W2611190100 modified "2023-10-09" @default.
• W2611190100 title "Cross-Metathesis/Intramolecular (Hetero-)Michael Addition: A Convenient Sequence for the Generation of Carbo- and Heterocycles" @default.
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• W2611190100 doi "https://doi.org/10.1055/s-0036-1589497" @default.
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