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- W2611213552 endingPage "1043" @default.
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- W2611213552 abstract "Introduction: In spite of modern techniques, the burden for patients with type 1 diabetes (T1D) will not disappear and T1D remains a life-threatening disease causing severe complications and increased mortality. We have to learn how to preserve residual insulin secretion or even increase beta cell regeneration. This would give a milder disease, simpler treatment and perhaps even cure. Thus, there are good reasons to try therapies that may preserve beta cell function.Areas covered: In this review the author reviews the literature and registered ongoing trials using GAD-alum put in relation to the high number of published different immune interventions.Expert opinion: GAD-alum treatment is safe, tolerable and easy for the patients and healthcare. It seems probable that treatment with GAD65-alum 20 µg sc can preserve residual beta cell function in T1D, but efficacy needs to be improved. This may be achieved by the use of combination therapies and new approaches for administration." @default.
- W2611213552 created "2017-05-12" @default.
- W2611213552 creator A5075567727 @default.
- W2611213552 date "2017-05-25" @default.
- W2611213552 modified "2023-09-27" @default.
- W2611213552 title "GAD65: a prospective vaccine for treating Type 1 diabetes?" @default.
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- W2611213552 doi "https://doi.org/10.1080/14712598.2017.1328495" @default.
- W2611213552 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28480759" @default.
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