Matches in SemOpenAlex for { <https://semopenalex.org/work/W261130727> ?p ?o ?g. }
Showing items 1 to 58 of
58
with 100 items per page.
- W261130727 abstract "Abstract : Organophosphorus (OP) nerve agents are a serious threat to military and civilian personnel, so rapid detection of OP compounds in all of these forms is of paramount importance to prevent casualties. Recently, we combined porous polyurethane foam formed in situ from water-miscible hydrophilic urethane prepolymers and enzymes such as ChEs. One of the advantages of this technique imparted to the immobilized enzymes is resistance to denaturing events. Most important, the enzyme will not leach from the polyurethane support so the ChE-badge can now be used to sample for OPs in diverse environments such as soil and large bodies of water, as well as conventional sources such as air. In addition, immobilized enzyme badges are being designed with a unique attribute not present in the current nonimmobilized detectors: a rapid field system to identifying which OP is present. For instance, organophosphorus hydrolase (OPH) hydrolyzes sarin more readily than soman, while laccase hydrolyzes the VX agent preferentially over the G agent OPs. Currently, we are evaluating polyurethane immobilized laccase for long-term stability and kinetic properties of VX hydrolysis. Thus, the immobilized sensor can provide new features and testing of more diverse environments than the M256A1 and M272 kits combined. Also, the ability to identify the OP toxin in real-time using the immobilized differential detector would aid in treatment and securing the contaminated area, in the identification of the use of OPs, and permitting first responders to identify the OP present in a civilian terrorist act." @default.
- W261130727 created "2016-06-24" @default.
- W261130727 creator A5021008057 @default.
- W261130727 creator A5029176560 @default.
- W261130727 creator A5056099092 @default.
- W261130727 creator A5072532517 @default.
- W261130727 creator A5083719662 @default.
- W261130727 date "2002-01-01" @default.
- W261130727 modified "2023-09-27" @default.
- W261130727 title "Selective, Specific, and Versatile Personal Biosensors to Organophosphate Chemical Toxins Composed of Polyurethane Immobilized Enzymes" @default.
- W261130727 hasPublicationYear "2002" @default.
- W261130727 type Work @default.
- W261130727 sameAs 261130727 @default.
- W261130727 citedByCount "0" @default.
- W261130727 crossrefType "journal-article" @default.
- W261130727 hasAuthorship W261130727A5021008057 @default.
- W261130727 hasAuthorship W261130727A5029176560 @default.
- W261130727 hasAuthorship W261130727A5056099092 @default.
- W261130727 hasAuthorship W261130727A5072532517 @default.
- W261130727 hasAuthorship W261130727A5083719662 @default.
- W261130727 hasConcept C178790620 @default.
- W261130727 hasConcept C181199279 @default.
- W261130727 hasConcept C185592680 @default.
- W261130727 hasConcept C2778706303 @default.
- W261130727 hasConcept C2778816929 @default.
- W261130727 hasConcept C2779578285 @default.
- W261130727 hasConcept C2780266723 @default.
- W261130727 hasConcept C2780292010 @default.
- W261130727 hasConcept C33633552 @default.
- W261130727 hasConcept C43617362 @default.
- W261130727 hasConcept C76935637 @default.
- W261130727 hasConcept C94412978 @default.
- W261130727 hasConceptScore W261130727C178790620 @default.
- W261130727 hasConceptScore W261130727C181199279 @default.
- W261130727 hasConceptScore W261130727C185592680 @default.
- W261130727 hasConceptScore W261130727C2778706303 @default.
- W261130727 hasConceptScore W261130727C2778816929 @default.
- W261130727 hasConceptScore W261130727C2779578285 @default.
- W261130727 hasConceptScore W261130727C2780266723 @default.
- W261130727 hasConceptScore W261130727C2780292010 @default.
- W261130727 hasConceptScore W261130727C33633552 @default.
- W261130727 hasConceptScore W261130727C43617362 @default.
- W261130727 hasConceptScore W261130727C76935637 @default.
- W261130727 hasConceptScore W261130727C94412978 @default.
- W261130727 hasLocation W2611307271 @default.
- W261130727 hasOpenAccess W261130727 @default.
- W261130727 hasPrimaryLocation W2611307271 @default.
- W261130727 hasRelatedWork W13851093 @default.
- W261130727 hasRelatedWork W1593951611 @default.
- W261130727 hasRelatedWork W1973579075 @default.
- W261130727 hasRelatedWork W261463547 @default.
- W261130727 hasRelatedWork W3021474753 @default.
- W261130727 hasRelatedWork W1513010504 @default.
- W261130727 hasRelatedWork W321557382 @default.
- W261130727 isParatext "false" @default.
- W261130727 isRetracted "false" @default.
- W261130727 magId "261130727" @default.
- W261130727 workType "article" @default.