Matches in SemOpenAlex for { <https://semopenalex.org/work/W2611388738> ?p ?o ?g. }
- W2611388738 endingPage "320" @default.
- W2611388738 startingPage "315" @default.
- W2611388738 abstract "Low pulmonary vascular resistance index (PVRI) reflects favorable redundant pulmonary circulation following coronary artery bypass grafting with cardiopulmonary bypass surgery (CPB). This randomized study investigated whether aprotinin given in different modalities impacts PVRI after coronary artery bypass grafting. A total of 40 patients undergoing coronary artery bypass grafting were randomized to four groups according to aprotinin dose: (1) high dose, (2) early low dose, (3) late low dose, and (4) without aprotinin. Oxygenation index, pulmonary shunt, alveolar-arterial oxygen gradient and PVRI were determined. PVRI was calculated as the transpulmonary pressure gradient divided by cardiac index multiplied by 80. The results showed that PVRI remained relative low in all patients provided aprotinin regardless of treatment dosage; PVRI increased at 4 h after restarting ventilation after CPB in patients without aprotinin as compared with aprotinin (266 ± 137, 266 ± 115, 244 ± 86 vs. 386 ± 121, dynes-s-cm-5, respectively, p = .047). Elevated postoperative PVRI was predictive for patients without aprotinin (AUC 0.668; SE 0.40; p < .0001; CI 0.590-0.746). There were no statistical differences in oxygenation index, pulmonary shunt or alveolar-arterial oxygen gradient between the groups. In conclusion, aprotinin maintains a low PVRI in elective patients with healthy lungs during CPB. We suggest that aprotinin maintains pulmonary arterial endothelial integrity." @default.
- W2611388738 created "2017-05-12" @default.
- W2611388738 creator A5001600698 @default.
- W2611388738 creator A5041292085 @default.
- W2611388738 creator A5080553980 @default.
- W2611388738 creator A5082162970 @default.
- W2611388738 creator A5084986778 @default.
- W2611388738 creator A5091098301 @default.
- W2611388738 date "2017-05-02" @default.
- W2611388738 modified "2023-09-24" @default.
- W2611388738 title "Pulmonary vascular resistance index during coronary artery bypass surgery with aprotinin" @default.
- W2611388738 cites W1987589661 @default.
- W2611388738 cites W1996462600 @default.
- W2611388738 cites W1996767888 @default.
- W2611388738 cites W2023002615 @default.
- W2611388738 cites W2025993108 @default.
- W2611388738 cites W2039617170 @default.
- W2611388738 cites W2047286220 @default.
- W2611388738 cites W2049406319 @default.
- W2611388738 cites W2052929658 @default.
- W2611388738 cites W2053542090 @default.
- W2611388738 cites W2061385284 @default.
- W2611388738 cites W2061799555 @default.
- W2611388738 cites W2062233783 @default.
- W2611388738 cites W2084339523 @default.
- W2611388738 cites W2100390758 @default.
- W2611388738 cites W2107522704 @default.
- W2611388738 cites W2110329740 @default.
- W2611388738 cites W2118597154 @default.
- W2611388738 cites W2122515339 @default.
- W2611388738 cites W2134400966 @default.
- W2611388738 cites W2145330473 @default.
- W2611388738 cites W2154036079 @default.
- W2611388738 cites W2154799252 @default.
- W2611388738 cites W2166130042 @default.
- W2611388738 cites W2242859312 @default.
- W2611388738 cites W2469316347 @default.
- W2611388738 cites W4241247031 @default.
- W2611388738 doi "https://doi.org/10.1080/00365513.2017.1318446" @default.
- W2611388738 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28460544" @default.
- W2611388738 hasPublicationYear "2017" @default.
- W2611388738 type Work @default.
- W2611388738 sameAs 2611388738 @default.
- W2611388738 citedByCount "1" @default.
- W2611388738 countsByYear W26113887382018 @default.
- W2611388738 crossrefType "journal-article" @default.
- W2611388738 hasAuthorship W2611388738A5001600698 @default.
- W2611388738 hasAuthorship W2611388738A5041292085 @default.
- W2611388738 hasAuthorship W2611388738A5080553980 @default.
- W2611388738 hasAuthorship W2611388738A5082162970 @default.
- W2611388738 hasAuthorship W2611388738A5084986778 @default.
- W2611388738 hasAuthorship W2611388738A5091098301 @default.
- W2611388738 hasConcept C126322002 @default.
- W2611388738 hasConcept C139940330 @default.
- W2611388738 hasConcept C164705383 @default.
- W2611388738 hasConcept C178853913 @default.
- W2611388738 hasConcept C2776820930 @default.
- W2611388738 hasConcept C2778881276 @default.
- W2611388738 hasConcept C2780799893 @default.
- W2611388738 hasConcept C2780940725 @default.
- W2611388738 hasConcept C31861589 @default.
- W2611388738 hasConcept C42219234 @default.
- W2611388738 hasConcept C58245268 @default.
- W2611388738 hasConcept C70289976 @default.
- W2611388738 hasConcept C71924100 @default.
- W2611388738 hasConceptScore W2611388738C126322002 @default.
- W2611388738 hasConceptScore W2611388738C139940330 @default.
- W2611388738 hasConceptScore W2611388738C164705383 @default.
- W2611388738 hasConceptScore W2611388738C178853913 @default.
- W2611388738 hasConceptScore W2611388738C2776820930 @default.
- W2611388738 hasConceptScore W2611388738C2778881276 @default.
- W2611388738 hasConceptScore W2611388738C2780799893 @default.
- W2611388738 hasConceptScore W2611388738C2780940725 @default.
- W2611388738 hasConceptScore W2611388738C31861589 @default.
- W2611388738 hasConceptScore W2611388738C42219234 @default.
- W2611388738 hasConceptScore W2611388738C58245268 @default.
- W2611388738 hasConceptScore W2611388738C70289976 @default.
- W2611388738 hasConceptScore W2611388738C71924100 @default.
- W2611388738 hasFunder F4320326518 @default.
- W2611388738 hasIssue "5" @default.
- W2611388738 hasLocation W26113887381 @default.
- W2611388738 hasLocation W26113887382 @default.
- W2611388738 hasOpenAccess W2611388738 @default.
- W2611388738 hasPrimaryLocation W26113887381 @default.
- W2611388738 hasRelatedWork W2010738716 @default.
- W2611388738 hasRelatedWork W2046852523 @default.
- W2611388738 hasRelatedWork W2054032064 @default.
- W2611388738 hasRelatedWork W2134878907 @default.
- W2611388738 hasRelatedWork W2163738214 @default.
- W2611388738 hasRelatedWork W2356827941 @default.
- W2611388738 hasRelatedWork W2373383281 @default.
- W2611388738 hasRelatedWork W2415579241 @default.
- W2611388738 hasRelatedWork W2475327391 @default.
- W2611388738 hasRelatedWork W2096901498 @default.
- W2611388738 hasVolume "77" @default.
- W2611388738 isParatext "false" @default.
- W2611388738 isRetracted "false" @default.
- W2611388738 magId "2611388738" @default.