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• W2611485917 abstract "The introduction of a new technique based on molecular cytogenetics (the comparative genomic hybridization microarray, Chromosomal Micro-Array) in prenatal diagnosis is here used as an occasion to politically elaborate Cambrosio’s and Keating’s framework of “biomedical platform.” The uncertainty generated by molecularization leaves the field open for two different modalities of implementation: using targeted microarrays to completely replace traditional karyotyping versus using genome-wide analysis of chromosomal anomalies only in at-risk pregnancies. Retracing the global scientific controversy on this issue and, particularly, the heated debate that has taken place in Italy, the paper intends to analyze the rise of a biomedical platform in prenatal diagnosis as a multi-layered phenomenon. Diverging epistemological strategies to deal with uncertainty, professional interests, relationship between medical practice, innovation and research, and patient subjectivities interact with each other, by shedding ligh..." @default.
• W2611485917 created "2017-05-12" @default.
• W2611485917 creator A5012973960 @default.
• W2611485917 date "2017-04-03" @default.
• W2611485917 modified "2023-10-01" @default.
• W2611485917 title "The politics of biomedical platforms: controversy around the molecularization of cytogenetics in prenatal diagnosis" @default.
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• W2611485917 doi "https://doi.org/10.1080/14636778.2017.1302324" @default.
• W2611485917 hasPublicationYear "2017" @default.
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