FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2611670410> ?p ?o ?g. }

• W2611670410 endingPage "330" @default.
• W2611670410 startingPage "325" @default.
• W2611670410 abstract "Abstract The design of artificial metalloenzymes has achieved tremendous progress, although few designs can achieve catalytic performances comparable to that of native enzymes. Moreover, the structure and function of artificial metalloenzymes in non‐native states has rarely been explored. Herein, we found that a c ‐type cytochrome b 5 (Cyt b 5 ), N57C/S71C Cyt b 5 , with heme covalently attached to the protein matrix through two Cys–heme linkages, adopts a non‐native state with an open heme site after guanidine hydrochloride (Gdn ⋅ HCl)‐induced unfolding, which facilitates H 2 O 2 activation and substrate binding. Stopped‐flow kinetic studies further revealed that c ‐type Cyt b 5 in the non‐native state exhibited impressive peroxidase activity comparable to that of native peroxidases, such as the most efficient horseradish peroxidase. This study presents an alternative approach to the design of functional artificial metalloenzymes by exploring enzymatic functions in non‐native states." @default.
• W2611670410 created "2017-05-12" @default.
• W2611670410 creator A5008707460 @default.
• W2611670410 creator A5017025191 @default.
• W2611670410 creator A5061327877 @default.
• W2611670410 creator A5068767397 @default.
• W2611670410 creator A5068902273 @default.
• W2611670410 creator A5080935121 @default.
• W2611670410 date "2017-05-02" @default.
• W2611670410 modified "2023-10-16" @default.
• W2611670410 title "Peroxidase Activity of a <i>c</i> -Type Cytochrome <i>b</i> ₅ in the Non-Native State is Comparable to that of Native Peroxidases" @default.
• W2611670410 cites W1822158303 @default.
• W2611670410 cites W1963602638 @default.
• W2611670410 cites W1966935274 @default.
• W2611670410 cites W1966994406 @default.
• W2611670410 cites W1973326808 @default.
• W2611670410 cites W1974104064 @default.
• W2611670410 cites W1977461498 @default.
• W2611670410 cites W1978592925 @default.
• W2611670410 cites W1983392880 @default.
• W2611670410 cites W1983692137 @default.
• W2611670410 cites W1990618198 @default.
• W2611670410 cites W2000739420 @default.
• W2611670410 cites W2006999117 @default.
• W2611670410 cites W2012159502 @default.
• W2611670410 cites W2012837790 @default.
• W2611670410 cites W2015402977 @default.
• W2611670410 cites W2024246479 @default.
• W2611670410 cites W2024296243 @default.
• W2611670410 cites W2025039872 @default.
• W2611670410 cites W2026036565 @default.
• W2611670410 cites W2032542581 @default.
• W2611670410 cites W2034971743 @default.
• W2611670410 cites W2039130521 @default.
• W2611670410 cites W2044705084 @default.
• W2611670410 cites W2046060561 @default.
• W2611670410 cites W2068017837 @default.
• W2611670410 cites W2068976234 @default.
• W2611670410 cites W2083353493 @default.
• W2611670410 cites W2083608501 @default.
• W2611670410 cites W2087126343 @default.
• W2611670410 cites W2092815591 @default.
• W2611670410 cites W2120852426 @default.
• W2611670410 cites W2152474894 @default.
• W2611670410 cites W2153089815 @default.
• W2611670410 cites W2161700805 @default.
• W2611670410 cites W2168635905 @default.
• W2611670410 cites W2269688327 @default.
• W2611670410 cites W2294942216 @default.
• W2611670410 cites W2296423762 @default.
• W2611670410 cites W2314900960 @default.
• W2611670410 cites W2322918395 @default.
• W2611670410 cites W2339294105 @default.
• W2611670410 cites W2465674018 @default.
• W2611670410 cites W2531841108 @default.
• W2611670410 cites W2553658517 @default.
• W2611670410 cites W2569641753 @default.
• W2611670410 cites W404486077 @default.
• W2611670410 cites W4239086335 @default.
• W2611670410 cites W4239524942 @default.
• W2611670410 cites W573546625 @default.
• W2611670410 cites W631297584 @default.
• W2611670410 doi "https://doi.org/10.1002/open.201700055" @default.
• W2611670410 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5474653" @default.
• W2611670410 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28638761" @default.
• W2611670410 hasPublicationYear "2017" @default.
• W2611670410 type Work @default.
• W2611670410 sameAs 2611670410 @default.
• W2611670410 citedByCount "9" @default.
• W2611670410 countsByYear W26116704102017 @default.
• W2611670410 countsByYear W26116704102018 @default.
• W2611670410 countsByYear W26116704102019 @default.
• W2611670410 countsByYear W26116704102020 @default.
• W2611670410 countsByYear W26116704102021 @default.
• W2611670410 countsByYear W26116704102022 @default.
• W2611670410 countsByYear W26116704102023 @default.
• W2611670410 crossrefType "journal-article" @default.
• W2611670410 hasAuthorship W2611670410A5008707460 @default.
• W2611670410 hasAuthorship W2611670410A5017025191 @default.
• W2611670410 hasAuthorship W2611670410A5061327877 @default.
• W2611670410 hasAuthorship W2611670410A5068767397 @default.
• W2611670410 hasAuthorship W2611670410A5068902273 @default.
• W2611670410 hasAuthorship W2611670410A5080935121 @default.
• W2611670410 hasBestOaLocation W26116704101 @default.
• W2611670410 hasConcept C133166286 @default.
• W2611670410 hasConcept C147816474 @default.
• W2611670410 hasConcept C152769699 @default.
• W2611670410 hasConcept C162008176 @default.
• W2611670410 hasConcept C181199279 @default.
• W2611670410 hasConcept C185592680 @default.
• W2611670410 hasConcept C18903297 @default.
• W2611670410 hasConcept C19472624 @default.
• W2611670410 hasConcept C20705724 @default.
• W2611670410 hasConcept C21951064 @default.
• W2611670410 hasConcept C2776217839 @default.
• W2611670410 hasConcept C2777289219 @default.
• W2611670410 hasConcept C2777676563 @default.
• W2611670410 hasConcept C2779463914 @default.

• next