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- W2611883305 abstract "ResumoObjetivo: Trabalhos de pesquisa provenientes do campo da neuroimunomodulacao vem tornando explicitas as intrincadasrelacoes existentes entre o sistema nervoso central e o sistema imune. Uma revisao bibliografica foi realizada com o objetivo dedescrever as bases de estudo da neuroimunomodulacao. Modelos experimentais: Sabe-se, hoje, que estados emocionaiscomo ansiedade e depressao sao capazes de modificar a atividade do sistema imune como tambem o fazem o estresse e farmacoscom acao no sistema nervoso central. Comportamento doentio: Os comportamentos apresentados por um organismo doentedevem ser encarados como decorrencia de estrategias homeostaticas de cada individuo. Possiveis mecanismos de sinaliza-cao do sistema imune para o sistema nervoso central: Grande destaque tem sido atribuido para a participacao do eixohipotalamo-pituitaria-adrenal, do sistema nervoso autonomo simpatico e das citocinas nas sinalizacoes entre o sistema nervosocentral e o sistema imune. Conclusao: O presente artigo pretende mostrar a relevância dos fenomenos de neuroimunomodulacao;ele faz uma analise critica das influencias do sistema nervoso central sobre o sistema imune e vice-versa.Descritores: Neuroimunomodulacao; Estresse; Sistema hipotalamo-hipofisario; Sistema pituitario-adrenal; Sistema nervoso simpaticoAbstractObjective: Several papers arriving from the neuroimmunomodulation field are showing the relevant relationships between thenervous and the immune systems. A review of studies was carried out to describe the bases of the studies on neuroimmunomodulati on.Experimental models: It is clear nowadays that emotional states such as anxiety and depression change immune systemactivity, an affect also observed after both stress and use of nervous system acting drugs. Sick behavior: The behavior displayedby sick organisms might be thought as being a consequence of homeostatic strategies. Possible mechanism of the action bymeans of immune system to nervous system: A very big emphasis is being given to Hipothalamus-pituitary-adrenal axis,simpathetic nervous system and cytokines participation on nervous system and immune system relationships. Conclusion: Thepresent revision intend to show some essential studies in the neuroimmunomodulation field; it makes a critical analysis of themutual relationships between nervous system and immune system.Descriptors: Neuroimmunomodulation; Stress; Hypothalamus-hypophyseal system; Pituitary adrenal system; Sympatheticnervous system" @default.
- W2611883305 created "2017-05-12" @default.
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- W2611883305 date "2007-12-01" @default.
- W2611883305 modified "2023-10-16" @default.
- W2611883305 title "Neuroimunomodulação: sobre o diálogo entre os sistemas nervoso e imune Neuroimmunomodulation: the cross-talk between nervous and immune systems" @default.
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