FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2611891919> ?p ?o ?g. }

• W2611891919 endingPage "250" @default.
• W2611891919 startingPage "245" @default.
• W2611891919 abstract "Higher exposure to tenofovir (TFV) increases the risk for kidney function decline, but the impact of genetic factors on TFV exposure is largely unknown. We investigated whether single-nucleotide polymorphisms (SNPs, n=211) in 12 genes are potentially involved in TFV exposure. Participants (n=91) from the Women’s Interagency HIV Study, underwent a 24 h intensive pharmacokinetic sampling of TFV after witnessed dose and TFV area under the time–concentration curves (AUCs) were calculated for each participant. SNPs were assayed using a combination of array genotyping and Sanger sequencing. Linear regression models were applied to logarithmically transformed AUC. Those SNPs that met an a priori threshold of P<0.001 were considered statistically associated with TFV AUC. ABCG2 SNP rs2231142 was associated with TFV AUC with rare allele carriers displaying 1.51-fold increase in TFV AUC (95% confidence interval: 1.26, 1.81; P=1.7 × 10−5). We present evidence of a moderately strong effect of the rs2231142 SNP in ABCG2 on a 24 h TFV AUC." @default.
• W2611891919 created "2017-05-12" @default.
• W2611891919 creator A5069467129 @default.
• W2611891919 date "2017-05-02" @default.
• W2611891919 modified "2023-09-26" @default.
• W2611891919 title "Evaluating the association of single-nucleotide polymorphisms with tenofovir exposure in a diverse prospective cohort of women living with HIV" @default.
• W2611891919 cites W1963944716 @default.
• W2611891919 cites W1966436517 @default.
• W2611891919 cites W1967879506 @default.
• W2611891919 cites W1977189552 @default.
• W2611891919 cites W1986250953 @default.
• W2611891919 cites W1986694485 @default.
• W2611891919 cites W1990722950 @default.
• W2611891919 cites W1990951677 @default.
• W2611891919 cites W1992392338 @default.
• W2611891919 cites W1992616691 @default.
• W2611891919 cites W1996702074 @default.
• W2611891919 cites W2003529614 @default.
• W2611891919 cites W2003990352 @default.
• W2611891919 cites W2006535221 @default.
• W2611891919 cites W2009136130 @default.
• W2611891919 cites W2009422948 @default.
• W2611891919 cites W2010002499 @default.
• W2611891919 cites W2011286432 @default.
• W2611891919 cites W2023418826 @default.
• W2611891919 cites W2027416226 @default.
• W2611891919 cites W2030111839 @default.
• W2611891919 cites W2035212948 @default.
• W2611891919 cites W2036201513 @default.
• W2611891919 cites W2044444556 @default.
• W2611891919 cites W2044932421 @default.
• W2611891919 cites W2057341487 @default.
• W2611891919 cites W2065341870 @default.
• W2611891919 cites W2078467477 @default.
• W2611891919 cites W2084945406 @default.
• W2611891919 cites W2089914064 @default.
• W2611891919 cites W2090261939 @default.
• W2611891919 cites W2093300338 @default.
• W2611891919 cites W2095607708 @default.
• W2611891919 cites W2097781012 @default.
• W2611891919 cites W2099746597 @default.
• W2611891919 cites W2102661607 @default.
• W2611891919 cites W2102758806 @default.
• W2611891919 cites W2106737113 @default.
• W2611891919 cites W2107869736 @default.
• W2611891919 cites W2109229072 @default.
• W2611891919 cites W2120454545 @default.
• W2611891919 cites W2126394114 @default.
• W2611891919 cites W2128934212 @default.
• W2611891919 cites W2134512816 @default.
• W2611891919 cites W2138433402 @default.
• W2611891919 cites W2139178927 @default.
• W2611891919 cites W2141876271 @default.
• W2611891919 cites W2166174569 @default.
• W2611891919 cites W2167794954 @default.
• W2611891919 cites W2418793062 @default.
• W2611891919 cites W2469433441 @default.
• W2611891919 cites W3207530515 @default.
• W2611891919 doi "https://doi.org/10.1038/tpj.2017.3" @default.
• W2611891919 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7793629" @default.
• W2611891919 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28462920" @default.
• W2611891919 hasPublicationYear "2017" @default.
• W2611891919 type Work @default.
• W2611891919 sameAs 2611891919 @default.
• W2611891919 citedByCount "10" @default.
• W2611891919 countsByYear W26118919192017 @default.
• W2611891919 countsByYear W26118919192019 @default.
• W2611891919 countsByYear W26118919192020 @default.
• W2611891919 countsByYear W26118919192021 @default.
• W2611891919 countsByYear W26118919192022 @default.
• W2611891919 countsByYear W26118919192023 @default.
• W2611891919 crossrefType "journal-article" @default.
• W2611891919 hasAuthorship W2611891919A5069467129 @default.
• W2611891919 hasBestOaLocation W26118919192 @default.
• W2611891919 hasConcept C104317684 @default.
• W2611891919 hasConcept C126322002 @default.
• W2611891919 hasConcept C135763542 @default.
• W2611891919 hasConcept C139275648 @default.
• W2611891919 hasConcept C153209595 @default.
• W2611891919 hasConcept C163691529 @default.
• W2611891919 hasConcept C31467283 @default.
• W2611891919 hasConcept C44249647 @default.
• W2611891919 hasConcept C51679486 @default.
• W2611891919 hasConcept C54355233 @default.
• W2611891919 hasConcept C71924100 @default.
• W2611891919 hasConcept C76818968 @default.
• W2611891919 hasConcept C86803240 @default.
• W2611891919 hasConceptScore W2611891919C104317684 @default.
• W2611891919 hasConceptScore W2611891919C126322002 @default.
• W2611891919 hasConceptScore W2611891919C135763542 @default.
• W2611891919 hasConceptScore W2611891919C139275648 @default.
• W2611891919 hasConceptScore W2611891919C153209595 @default.
• W2611891919 hasConceptScore W2611891919C163691529 @default.
• W2611891919 hasConceptScore W2611891919C31467283 @default.
• W2611891919 hasConceptScore W2611891919C44249647 @default.
• W2611891919 hasConceptScore W2611891919C51679486 @default.
• W2611891919 hasConceptScore W2611891919C54355233 @default.
• W2611891919 hasConceptScore W2611891919C71924100 @default.

• next