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• W2612110009 abstract "Purpose. The authors evaluated the diagnostic accuracy of second-generation dual-source (DSCT) computed tomography coronary angiography (CTCA) with iterative reconstructions for detecting obstructive coronary artery disease (CAD). Materials and methods. Between June 2010 and February 2011, we enrolled 160 patients (85 men; mean age 61.2±11.6 years) with suspected CAD. All patients underwent CTCA and conventional coronary angiography (CCA). For the CTCA scan (Definition Flash, Siemens), we use prospective tube current modulation and 70–100 ml of iodinated contrast material (Iomeprol 400 mgI/ ml, Bracco). Data sets were reconstructed with iterative reconstruction algorithm (IRIS, Siemens). CTCA and CCA reports were used to evaluate accuracy using the threshold for significant stenosis at ≥50% and ≥70%, respectively. Results. No patient was excluded from the analysis. Heart rate was 64.3±11.9 bpm and radiation dose was 7.2±2.1 mSv. Disease prevalence was 30% (48/160). Sensitivity, specificity and positive and negative predictive values Riassunto Obiettivo. Scopo del presente lavoro e stato valutare l’accuratezza diagnostica dell’angiografia coronarica non invasiva con tomografia computerizzata (CTCA) a doppia sorgente (DSCT) di seconda generazione (64×2×2 strati) con ricostruzioni iterative, nell’individuazione della malattia coronarica (CAD) ostruttiva. Materiali e metodi. Tra giugno 2010 e febbraio 2011 sono stati arruolati nello studio 160 pazienti (85 maschi, eta media 61,2±11,6 anni) con sospetta malattia coronarica. Tutti i pazienti sono stati sottoposti a CTCA e coronarografia convenzionale (CAG). Per la scansione CTCA e stata utilizzata la modulazione prospettica dell’amperaggio e 70–100 ml di mezzo di contrasto. I dataset sono stati ricostruiti con algoritmi iterativi. I referti della CTCA e della CAG sono utilizzati per la valutazione dell’accuratezza diagnostica utilizzano la definizione di stenosi ≥50% per la CTCA e ≥70% per la CAG. Risultati. Nessun paziente e stato escluso dall’analisi. La frequenza cardiaca media e stata 64,3±11,9 battiti per minuto (bpm) e la dose media 7,2±2,1 mSv. La prevalenza CARDIAC RADIOLOGY CARDIORADIOLOGIA Diagnostic accuracy of second-generation dual-source computed tomography coronary angiography with iterative reconstructions: a real-world experience Accuratezza diagnostica dell’angiografia coronarica con tomografia computerizzata a doppia sorgente di seconda generazione con ricostruzioni iterative: valutazione nel mondo reale E. Maffei1 • C. Martini1 • A. Rossi2 • N. Mollet2 • C. Lario3 • M. Castiglione Morelli4 A. Clemente5 • G. Gentile6 • T. Arcadi7 • S. Seitun4 • O. Catalano8 • A. Aldrovandi9 F. Cademartiri1,2 Unita Cardio-Vascolare Radiologica, Ospedale Giovanni XXIII, Monastier di Treviso (TV), Italy Dipartimento di Radiologia e Cardiologia, Erasmus Medical Center, Rotterdam, The Netherlands Dipartimento di Radiologia, Universita di Torino, Italy Dipartimento di Radiologia, Universita di Genova, Italy Dipartimento di Radiologia, Universita di Ferrara, Italy Dipartimento di Radiologia, Universita di Palermo, Italy Dipartimento di Radiologia, Universita di Messina, Italy Dipartimento di Radiologia, Fondazione SDN-IRCCS, Napoli, Italy Dipartimento di Cardiologia, Azienda Ospedaliero-Universitaria di Parma, Italy Correspondence to: F. Cademartiri, Unita Cardio-Vascolare Radiologica, Ospedale Giovanni XXIII, Via Giovanni XXIII 1, 31050 Monastier di Treviso (TV), Italy, Tel.: +39-0422-8961, Fax: +39-0422-898051, e-mail: filippocademartiri@gmail.com Received: 19 March 2011 /Accepted: 6 June 2011 © Springer-Verlag 2011" @default.
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• W2612110009 title "Diagnostic accuracy of second-generation dual-source computed tomography coronary angiography with iterative reconstructions: a real-world experience Accuratezza diagnostica dell’angiografia coronarica con tomografia computerizzata a doppia sorgente di seconda generazione con ricostruzioni iterative: valutazione nel mondo reale" @default.
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