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- W2612210321 abstract "Objective We aimed to determine whether individuals with obsessive-compulsive disorder (OCD) and demographically matched healthy individuals can be clustered into distinct clinical subtypes based on dimensional measures of their self-reported compulsivity (OBQ–44 and IUS–12) and impulsivity (UPPS–P). Methods Participants ( n =217) were 103 patients with a clinical diagnosis of OCD; 79 individuals from the community who were “OCD-likely” according to self-report (Obsessive-Compulsive Inventory–Revised scores equal or greater than 21); and 35 healthy controls. All data were collected between 2013 and 2015 using self-report measures that assessed different aspects of compulsivity and impulsivity. Principal component analysis revealed two components broadly representing an individual's level of compulsivity and impulsivity. Unsupervised clustering grouped participants into four subgroups, each representing one part of an orthogonal compulsive-impulsive phenotype. Results Clustering converged to yield four subgroups: one group low on both compulsivity and impulsivity, comprised mostly of healthy controls and demonstrating the lowest OCD symptom severity; two groups showing roughly equal clinical severity, but with opposing drivers (i.e., high compulsivity and low impulsivity, and vice versa); and a final group high on both compulsivity and impulsivity and recording the highest clinical severity. Notably, the largest cluster of individuals with OCD was characterized by high impulsivity and low compulsivity. Our results suggest that both impulsivity and compulsivity mediate obsessive-compulsive symptomatology. Conclusions Individuals with OCD can be clustered into distinct subtypes based on measures of compulsivity and impulsivity, with the latter being found to be one of the more defining characteristics of the disorder. These dimensions may serve as viable and novel treatment targets." @default.
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- W2612210321 date "2017-05-10" @default.
- W2612210321 modified "2023-10-12" @default.
- W2612210321 title "Unpacking the role of self-reported compulsivity and impulsivity in obsessive-compulsive disorder" @default.
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- W2612210321 cites W1983179387 @default.
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- W2612210321 cites W2001930853 @default.
- W2612210321 cites W2015665813 @default.
- W2612210321 cites W2021020861 @default.
- W2612210321 cites W2022372742 @default.
- W2612210321 cites W2024066498 @default.
- W2612210321 cites W2025860484 @default.
- W2612210321 cites W2034593916 @default.
- W2612210321 cites W2039903507 @default.
- W2612210321 cites W2045825611 @default.
- W2612210321 cites W2050611840 @default.
- W2612210321 cites W2051045414 @default.
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- W2612210321 doi "https://doi.org/10.1017/s1092852917000244" @default.
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