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• W2612443602 abstract "Background Whether outcomes differ between sexes following treatment with pacemakers ( PM ), implantable cardioverter defibrillators, and cardiac resynchronization therapy ( CRT ) devices is unclear. Methods and Results Consecutive US patients with newly implanted PM , implantable cardioverter defibrillators, and CRT devices from a large remote monitoring database between 2008 and 2011 were included in this observational cohort study. Sex‐specific all‐cause survival postimplant was compared within each device type using a multivariable Cox proportional hazards model, stratified on age and adjusted for remote monitoring utilization and ZIP ‐based socioeconomic variables. A total of 269 471 patients were assessed over a median 2.9 [interquartile range, 2.2, 3.6] years. Unadjusted mortality rates ( MR ; deaths/100 000 patient‐years) were similar between women versus men receiving PM s (n=115 076, 55% male; MR 4193 versus MR 4256, respectively; adjusted hazard ratio, 0.87; 95% CI , 0.84–0.90; P <0.001) and implantable cardioverter defibrillators (n=85 014, 74% male; MR 4417 versus MR 4479, respectively; adjusted hazard ratio, 0.98; 95% CI , 0.93–1.02; P =0.244). In contrast, survival was superior in women receiving CRT defibrillators (n=61 475, 72% male; MR 5270 versus male MR 7175; adjusted hazard ratio, 0.73; 95% CI , 0.70–0.76; P <0.001) and also CRT pacemakers (n=7906, 57% male; MR 5383 versus male MR 7625, adjusted hazard ratio, 0.69; 95% CI , 0.61–0.78; P <0.001). This relative difference increased with time. These results were unaffected by age or remote monitoring utilization. Conclusions Women accounted for less than 30% of high‐voltage implants and fewer than half of low‐voltage implants in a large, nation‐wide cohort. Survival for women and men receiving implantable cardioverter defibrillators and PM s was similar, but dramatically greater for women receiving both defibrillator‐ and PM‐based CRT ." @default.
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• W2612443602 date "2017-05-05" @default.
• W2612443602 modified "2023-10-16" @default.
• W2612443602 title "Survival in Women Versus Men Following Implantation of Pacemakers, Defibrillators, and Cardiac Resynchronization Therapy Devices in a Large, Nationwide Cohort" @default.
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• W2612443602 doi "https://doi.org/10.1161/jaha.116.005031" @default.
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