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- W2612587830 abstract "Summary Therelative prevalence ofabnormalities ofcoronary flowreserve andoesophageal function wasascertained in32syndrome X patients withtypical angina chest pain, apositive exercise test, andnormalcoronaryarteries. Coronary flowreserve in response toahyperaemic doseofpapaverinewas measuredusingan intracoronary Dopplercatheter positioned in theleftanteriordescending coronary artery. An abnormalcoronaryflow reservewas definedas being< 3.0. Patientswere investigated for oesophageal dysfunction bymanometry and 24-hourpH monitoring. Thirteen patients hadanimpaired coronary flow reserve (group1)and19patients hada normalflowreserve (group2).Eightof the13group1patients (62%)and13ofthe 19group2 patients (68%,p=NS)had evidence ofoesophageal dysfunction on eithermanometryor pH studies. Therefore, atotal of26(81%)syndrome X patients hadeither an abnormality of coronary flowreserveor oesophageal dysfunction suggesting thatchest painin thesepatients maybeduetomyocardial ischaemia or oesophageal dysfunction, thus confirming the heterogeneous natureofthissyndrome. Theprevalence of oesophageal abnormalities was independent ofanyabnormalities ofcoronaryflowreserve." @default.
- W2612587830 created "2017-05-19" @default.
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- W2612587830 date "2017-01-01" @default.
- W2612587830 modified "2023-09-23" @default.
- W2612587830 title "Coronary flowreserve andoesophageal dysfunction insyndrome X" @default.
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