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• W2612778081 endingPage "185" @default.
• W2612778081 startingPage "175" @default.
• W2612778081 abstract "Nonsense-mediated mRNA decay (NMD) is a surveillance mechanism ensuring the fast decay of mRNAs harboring a premature termination codon (PTC). As a quality control mechanism, NMD distinguishes PTCs from normal termination codons in order to degrade PTC-carrying mRNAs only. For this, NMD is connected to various other cell processes which regulate or activate it under specific cell conditions or in response to mutations, mis-regulations, stresses, or particular cell programs. These cell processes and their connections with NMD are the focus of this review, which aims both to illustrate the complexity of the NMD mechanism and its regulation and to highlight the cellular consequences of NMD inhibition. [BMB Reports 2017; 50(4): 175-185]." @default.
• W2612778081 created "2017-05-19" @default.
• W2612778081 creator A5001937617 @default.
• W2612778081 date "2017-04-30" @default.
• W2612778081 modified "2023-10-16" @default.
• W2612778081 title "Nonsense-mediated mRNA decay at the crossroads of many cellular pathways" @default.
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