Matches in SemOpenAlex for { <https://semopenalex.org/work/W2613276742> ?p ?o ?g. }
- W2613276742 endingPage "26" @default.
- W2613276742 startingPage "14" @default.
- W2613276742 abstract "We describe and evaluate an integrative hypothesis for helping to explain the major neurocognitive features of individuals with Williams syndrome region deletions and duplications. First, we demonstrate how the cognitive differences between Williams syndrome individuals, individuals with duplications of this region, and healthy individuals parallel the differences between individuals subject to effects of increased or decreased oxytocin. Second, we synthesize evidence showing that variation in expression of the gene GTF2I (General Transcription Factor II-I) underlies the primary social phenotypes of Williams syndrome and that common genetic variation in GTF2I mediates oxytocin reactivity, and its correlates, in healthy populations. Third, we describe findings relevant to the hypothesis that the GTF2I gene is subject to parent of origin effects whose behavioral expression fits with predictions from the kinship theory of genomic imprinting. Fourth, we describe how Williams syndrome can be considered, in part, as an autistic syndrome of Lorna Wing's 'active-but-odd' autism subtype, in contrast to associations of duplications with both schizophrenia and autism." @default.
- W2613276742 created "2017-05-19" @default.
- W2613276742 creator A5074013039 @default.
- W2613276742 creator A5089912926 @default.
- W2613276742 date "2017-08-01" @default.
- W2613276742 modified "2023-09-23" @default.
- W2613276742 title "Williams syndrome deletions and duplications: Genetic windows to understanding anxiety, sociality, autism, and schizophrenia" @default.
- W2613276742 cites W1489581569 @default.
- W2613276742 cites W1510464959 @default.
- W2613276742 cites W1757719852 @default.
- W2613276742 cites W1848963797 @default.
- W2613276742 cites W1880044083 @default.
- W2613276742 cites W1937686758 @default.
- W2613276742 cites W1938483190 @default.
- W2613276742 cites W1963545558 @default.
- W2613276742 cites W1964318976 @default.
- W2613276742 cites W1964979302 @default.
- W2613276742 cites W1966492135 @default.
- W2613276742 cites W1967894242 @default.
- W2613276742 cites W1968178768 @default.
- W2613276742 cites W1969197353 @default.
- W2613276742 cites W1970293309 @default.
- W2613276742 cites W1970445122 @default.
- W2613276742 cites W1970660276 @default.
- W2613276742 cites W1971319935 @default.
- W2613276742 cites W1973339596 @default.
- W2613276742 cites W1974168074 @default.
- W2613276742 cites W1974253747 @default.
- W2613276742 cites W1974473301 @default.
- W2613276742 cites W1974748816 @default.
- W2613276742 cites W1975252720 @default.
- W2613276742 cites W1976149688 @default.
- W2613276742 cites W1976695083 @default.
- W2613276742 cites W1977044662 @default.
- W2613276742 cites W1977164658 @default.
- W2613276742 cites W1978946302 @default.
- W2613276742 cites W1979373680 @default.
- W2613276742 cites W1983037600 @default.
- W2613276742 cites W1984642682 @default.
- W2613276742 cites W1985790741 @default.
- W2613276742 cites W1987482278 @default.
- W2613276742 cites W1987706867 @default.
- W2613276742 cites W1988473644 @default.
- W2613276742 cites W1988643592 @default.
- W2613276742 cites W1988815026 @default.
- W2613276742 cites W1988822374 @default.
- W2613276742 cites W1989435604 @default.
- W2613276742 cites W1989752168 @default.
- W2613276742 cites W1992073151 @default.
- W2613276742 cites W1993275955 @default.
- W2613276742 cites W1993685258 @default.
- W2613276742 cites W1994019510 @default.
- W2613276742 cites W1996190920 @default.
- W2613276742 cites W1998317396 @default.
- W2613276742 cites W2001784412 @default.
- W2613276742 cites W2004762465 @default.
- W2613276742 cites W2005609944 @default.
- W2613276742 cites W2005631411 @default.
- W2613276742 cites W2007180076 @default.
- W2613276742 cites W2007384358 @default.
- W2613276742 cites W2007544773 @default.
- W2613276742 cites W2009023961 @default.
- W2613276742 cites W2010098518 @default.
- W2613276742 cites W2010848180 @default.
- W2613276742 cites W2012203722 @default.
- W2613276742 cites W2012615017 @default.
- W2613276742 cites W2013188446 @default.
- W2613276742 cites W2014542294 @default.
- W2613276742 cites W2017342751 @default.
- W2613276742 cites W2017643219 @default.
- W2613276742 cites W2017720947 @default.
- W2613276742 cites W2019263033 @default.
- W2613276742 cites W2020590257 @default.
- W2613276742 cites W2021178751 @default.
- W2613276742 cites W2021377987 @default.
- W2613276742 cites W2022429467 @default.
- W2613276742 cites W2025147744 @default.
- W2613276742 cites W2026242270 @default.
- W2613276742 cites W2026585990 @default.
- W2613276742 cites W2027988800 @default.
- W2613276742 cites W2029300644 @default.
- W2613276742 cites W2029842229 @default.
- W2613276742 cites W2030288586 @default.
- W2613276742 cites W2031925105 @default.
- W2613276742 cites W2032344271 @default.
- W2613276742 cites W2032745668 @default.
- W2613276742 cites W2033325978 @default.
- W2613276742 cites W2033343038 @default.
- W2613276742 cites W2034052578 @default.
- W2613276742 cites W2034453108 @default.
- W2613276742 cites W2034793706 @default.
- W2613276742 cites W2035895525 @default.
- W2613276742 cites W2036733279 @default.
- W2613276742 cites W2037456827 @default.
- W2613276742 cites W2038559435 @default.
- W2613276742 cites W2038633541 @default.
- W2613276742 cites W2038764064 @default.
- W2613276742 cites W2039730733 @default.