FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2613305560> ?p ?o ?g. }

• W2613305560 endingPage "7" @default.
• W2613305560 startingPage "1" @default.
• W2613305560 abstract "The genus Chlorella contains unicellular green algae that have been used as food supplements. The purpose of this work was to evaluate the safety of the Chlorella sorokiniana strain CK-22 using powdered preparation (CK-22P) both by in vitro and in vivo assays. These included an experiment for cytotoxicity using Chinese hamster lung fibroblasts (V79 cells) and a 13-week repeated-dose oral toxicity trial using Wistar rats. The cytotoxicity was evaluated by MTT assay of a hot water extract (Hw-Ex) and 80% ethanol extract (Et-Ex) of CK-22P, and no effect on cell viability was observed. The 50% viability inhibitory effect (IC50) value for Hw-Ex and Et-Ex were estimated as greater than 73 and 17 μg/ml, respectively. In the subchronic toxicity test, pelleted rodent diet containing 0%, 2.5%, 5% or 10% CK-22P was given to Wistar rats (ten animals/sex/groups) for 13 weeks. During the experimental period, no CK-22P treatment-induced differences in general condition, body weight gain, food and water consumption, ophthalmology, urinalysis, hematology, clinical chemistry, gross pathology, organ weights, histopathology, or animal death were observed. The no-observed-adverse-effect levels (NOAEL) were estimated to be 5.94 g/kg body-weight/day for males and 6.41 g/kg body-weight/day for females." @default.
• W2613305560 created "2017-05-19" @default.
• W2613305560 creator A5005835940 @default.
• W2613305560 creator A5042624972 @default.
• W2613305560 creator A5046445805 @default.
• W2613305560 creator A5070652280 @default.
• W2613305560 creator A5086339539 @default.
• W2613305560 creator A5090507479 @default.
• W2613305560 date "2017-08-01" @default.
• W2613305560 modified "2023-10-16" @default.
• W2613305560 title "Safety evaluation of Chlorella sorokiniana strain CK-22 based on an in vitro cytotoxicity assay and a 13-week subchronic toxicity trial in rats" @default.
• W2613305560 cites W1016897078 @default.
• W2613305560 cites W1436817908 @default.
• W2613305560 cites W1974292012 @default.
• W2613305560 cites W1981795238 @default.
• W2613305560 cites W1990463877 @default.
• W2613305560 cites W1991927778 @default.
• W2613305560 cites W1997118199 @default.
• W2613305560 cites W2001139451 @default.
• W2613305560 cites W2016044284 @default.
• W2613305560 cites W2016273667 @default.
• W2613305560 cites W2022113955 @default.
• W2613305560 cites W2050323812 @default.
• W2613305560 cites W2055254758 @default.
• W2613305560 cites W2062142256 @default.
• W2613305560 cites W2065719392 @default.
• W2613305560 cites W2069271346 @default.
• W2613305560 cites W2088780443 @default.
• W2613305560 cites W2166112267 @default.
• W2613305560 cites W2320265638 @default.
• W2613305560 cites W2520586246 @default.
• W2613305560 cites W2605414924 @default.
• W2613305560 cites W2606488281 @default.
• W2613305560 cites W2607200523 @default.
• W2613305560 doi "https://doi.org/10.1016/j.fct.2017.05.025" @default.
• W2613305560 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28522334" @default.
• W2613305560 hasPublicationYear "2017" @default.
• W2613305560 type Work @default.
• W2613305560 sameAs 2613305560 @default.
• W2613305560 citedByCount "6" @default.
• W2613305560 countsByYear W26133055602018 @default.
• W2613305560 countsByYear W26133055602019 @default.
• W2613305560 countsByYear W26133055602020 @default.
• W2613305560 countsByYear W26133055602021 @default.
• W2613305560 countsByYear W26133055602022 @default.
• W2613305560 crossrefType "journal-article" @default.
• W2613305560 hasAuthorship W2613305560A5005835940 @default.
• W2613305560 hasAuthorship W2613305560A5042624972 @default.
• W2613305560 hasAuthorship W2613305560A5046445805 @default.
• W2613305560 hasAuthorship W2613305560A5070652280 @default.
• W2613305560 hasAuthorship W2613305560A5086339539 @default.
• W2613305560 hasAuthorship W2613305560A5090507479 @default.
• W2613305560 hasBestOaLocation W26133055601 @default.
• W2613305560 hasConcept C109316439 @default.
• W2613305560 hasConcept C116263406 @default.
• W2613305560 hasConcept C126322002 @default.
• W2613305560 hasConcept C140793950 @default.
• W2613305560 hasConcept C142724271 @default.
• W2613305560 hasConcept C150903083 @default.
• W2613305560 hasConcept C16685009 @default.
• W2613305560 hasConcept C202751555 @default.
• W2613305560 hasConcept C207001950 @default.
• W2613305560 hasConcept C26291073 @default.
• W2613305560 hasConcept C2777495288 @default.
• W2613305560 hasConcept C2779225474 @default.
• W2613305560 hasConcept C2779375934 @default.
• W2613305560 hasConcept C2780026642 @default.
• W2613305560 hasConcept C2781144631 @default.
• W2613305560 hasConcept C29730261 @default.
• W2613305560 hasConcept C33070731 @default.
• W2613305560 hasConcept C42407357 @default.
• W2613305560 hasConcept C544855455 @default.
• W2613305560 hasConcept C55493867 @default.
• W2613305560 hasConcept C559758991 @default.
• W2613305560 hasConcept C59822182 @default.
• W2613305560 hasConcept C71924100 @default.
• W2613305560 hasConcept C86803240 @default.
• W2613305560 hasConcept C98274493 @default.
• W2613305560 hasConceptScore W2613305560C109316439 @default.
• W2613305560 hasConceptScore W2613305560C116263406 @default.
• W2613305560 hasConceptScore W2613305560C126322002 @default.
• W2613305560 hasConceptScore W2613305560C140793950 @default.
• W2613305560 hasConceptScore W2613305560C142724271 @default.
• W2613305560 hasConceptScore W2613305560C150903083 @default.
• W2613305560 hasConceptScore W2613305560C16685009 @default.
• W2613305560 hasConceptScore W2613305560C202751555 @default.
• W2613305560 hasConceptScore W2613305560C207001950 @default.
• W2613305560 hasConceptScore W2613305560C26291073 @default.
• W2613305560 hasConceptScore W2613305560C2777495288 @default.
• W2613305560 hasConceptScore W2613305560C2779225474 @default.
• W2613305560 hasConceptScore W2613305560C2779375934 @default.
• W2613305560 hasConceptScore W2613305560C2780026642 @default.
• W2613305560 hasConceptScore W2613305560C2781144631 @default.
• W2613305560 hasConceptScore W2613305560C29730261 @default.
• W2613305560 hasConceptScore W2613305560C33070731 @default.
• W2613305560 hasConceptScore W2613305560C42407357 @default.
• W2613305560 hasConceptScore W2613305560C544855455 @default.
• W2613305560 hasConceptScore W2613305560C55493867 @default.

• next