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• W2613307082 abstract "subjective cognitive concerns (SCC) have been proposed as a means of identifying individuals at risk for Alzheimer's disease (AD). However, the utility of SCCs has not been well-explored for African-Americans, who are twice as likely to develop AD dementia as Caucasians. We investigated whether race affects the association between SCCs and objective memory performance. we used a composite of three SCC questionnaires, and three challenging episodic memory tests. We studied 289 (61% female; African-American n = 47) clinically normal older individuals. Two hierarchical linear regressions assessed the modifying role of race on the association between SCC and objective memory performance. The first regression was conducted on the full sample, while the second matched the racial groups on age, estimated verbal IQ and socioeconomic status. in the full sample, both groups reported similar levels of SCCs, P = 0.10, although African-Americans performed worse on the memory tasks, P < 0.001. No group differences were observed in the matched sample. The SCC × race interaction term was nonsignificant in the full sample, β = 0.109, P = 0.09, but was significant in the matched sample, β = 0.422, P = 0.037. While a significant correlation was observed between SCCs and memory among Caucasians, r = −0.401, the correlation was not found among African-Americans, r = −0.052. results suggest that the dissociation between SCCs and memory performance in African-Americans may indicate qualitative differences in how diverse groups endorse cognitive concerns, even after considering socioeconomic and educational factors." @default.
• W2613307082 created "2017-05-19" @default.
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• W2613307082 date "2017-05-10" @default.
• W2613307082 modified "2023-10-18" @default.
• W2613307082 title "Subjective cognitive concerns are associated with objective memory performance in Caucasian but not African-American persons" @default.
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• W2613307082 doi "https://doi.org/10.1093/ageing/afx077" @default.
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