Matches in SemOpenAlex for { <https://semopenalex.org/work/W2613349743> ?p ?o ?g. }
- W2613349743 endingPage "204" @default.
- W2613349743 startingPage "199" @default.
- W2613349743 abstract "Serotonin has a well-established role in emotional processing and is a key neurotransmitter in impulsive aggression, presumably by facilitating response inhibition and regulating subcortical reactivity to aversive stimuli. In this study 44 men, of whom 19 were violent offenders and 25 were non-offender controls, completed an emotional Go/NoGo task requiring inhibition of prepotent motor responses to emotional facial expressions. We also measured cerebral serotonin 1B receptor (5-HT1BR) binding with [11C]AZ10419369 positron emission tomography within regions of the frontal cortex. We hypothesized that 5-HT1BR would be positively associated with false alarms (failures to inhibit nogo responses) in the context of aversive (angry and fearful) facial expressions. Across groups, we found that frontal cortex 5-HT1BR binding was positively correlated with false alarms when angry faces were go stimuli and neutral faces were nogo stimuli (p = 0.05, corrected alpha = 0.0125), but not with false alarms for non-emotional stimuli (failures to inhibit geometric figures). A posthoc analysis revealed the strongest association in anterior cingulate cortex (p = 0.006). In summary, 5-HT1BRs in the anterior cingulate are involved in withholding a prepotent response in the context of angry faces. Our findings suggest that serotonin modulates response inhibition in the context of certain emotional stimuli." @default.
- W2613349743 created "2017-05-19" @default.
- W2613349743 creator A5004791170 @default.
- W2613349743 creator A5010674996 @default.
- W2613349743 creator A5015895924 @default.
- W2613349743 creator A5016724793 @default.
- W2613349743 creator A5070128576 @default.
- W2613349743 creator A5027524946 @default.
- W2613349743 date "2017-09-01" @default.
- W2613349743 modified "2023-10-03" @default.
- W2613349743 title "Anterior cingulate serotonin 1B receptor binding is associated with emotional response inhibition" @default.
- W2613349743 cites W1536737413 @default.
- W2613349743 cites W1969100427 @default.
- W2613349743 cites W1971416987 @default.
- W2613349743 cites W1977753224 @default.
- W2613349743 cites W1981086594 @default.
- W2613349743 cites W1984030600 @default.
- W2613349743 cites W1989848448 @default.
- W2613349743 cites W2007890394 @default.
- W2613349743 cites W2017307521 @default.
- W2613349743 cites W2026920081 @default.
- W2613349743 cites W2034010615 @default.
- W2613349743 cites W2047398419 @default.
- W2613349743 cites W2050618347 @default.
- W2613349743 cites W2050931725 @default.
- W2613349743 cites W2052366663 @default.
- W2613349743 cites W2053497768 @default.
- W2613349743 cites W2054515032 @default.
- W2613349743 cites W2063601827 @default.
- W2613349743 cites W2065320602 @default.
- W2613349743 cites W2066018239 @default.
- W2613349743 cites W2069331408 @default.
- W2613349743 cites W2085325217 @default.
- W2613349743 cites W2087209021 @default.
- W2613349743 cites W2088241529 @default.
- W2613349743 cites W2090114941 @default.
- W2613349743 cites W2091494281 @default.
- W2613349743 cites W2091953168 @default.
- W2613349743 cites W2092787182 @default.
- W2613349743 cites W2095821008 @default.
- W2613349743 cites W2099667563 @default.
- W2613349743 cites W2118969780 @default.
- W2613349743 cites W2121011110 @default.
- W2613349743 cites W2122941440 @default.
- W2613349743 cites W2126449881 @default.
- W2613349743 cites W2128342589 @default.
- W2613349743 cites W2131230499 @default.
- W2613349743 cites W2131665710 @default.
- W2613349743 cites W2133194768 @default.
- W2613349743 cites W2140443081 @default.
- W2613349743 cites W2153159895 @default.
- W2613349743 cites W2158164148 @default.
- W2613349743 cites W2168718397 @default.
- W2613349743 cites W2253237847 @default.
- W2613349743 cites W2294339574 @default.
- W2613349743 cites W2587395704 @default.
- W2613349743 cites W2596753163 @default.
- W2613349743 cites W4244986507 @default.
- W2613349743 cites W4292810003 @default.
- W2613349743 cites W573876062 @default.
- W2613349743 doi "https://doi.org/10.1016/j.jpsychires.2017.05.003" @default.
- W2613349743 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28502766" @default.
- W2613349743 hasPublicationYear "2017" @default.
- W2613349743 type Work @default.
- W2613349743 sameAs 2613349743 @default.
- W2613349743 citedByCount "8" @default.
- W2613349743 countsByYear W26133497432018 @default.
- W2613349743 countsByYear W26133497432019 @default.
- W2613349743 countsByYear W26133497432021 @default.
- W2613349743 countsByYear W26133497432022 @default.
- W2613349743 crossrefType "journal-article" @default.
- W2613349743 hasAuthorship W2613349743A5004791170 @default.
- W2613349743 hasAuthorship W2613349743A5010674996 @default.
- W2613349743 hasAuthorship W2613349743A5015895924 @default.
- W2613349743 hasAuthorship W2613349743A5016724793 @default.
- W2613349743 hasAuthorship W2613349743A5027524946 @default.
- W2613349743 hasAuthorship W2613349743A5070128576 @default.
- W2613349743 hasConcept C126322002 @default.
- W2613349743 hasConcept C138496976 @default.
- W2613349743 hasConcept C151730666 @default.
- W2613349743 hasConcept C15744967 @default.
- W2613349743 hasConcept C169760540 @default.
- W2613349743 hasConcept C169900460 @default.
- W2613349743 hasConcept C170493617 @default.
- W2613349743 hasConcept C195704467 @default.
- W2613349743 hasConcept C2775864247 @default.
- W2613349743 hasConcept C2776219046 @default.
- W2613349743 hasConcept C2778402161 @default.
- W2613349743 hasConcept C2779343474 @default.
- W2613349743 hasConcept C2779448149 @default.
- W2613349743 hasConcept C2781210436 @default.
- W2613349743 hasConcept C2910002191 @default.
- W2613349743 hasConcept C46312422 @default.
- W2613349743 hasConcept C529278444 @default.
- W2613349743 hasConcept C71924100 @default.
- W2613349743 hasConcept C86803240 @default.
- W2613349743 hasConceptScore W2613349743C126322002 @default.
- W2613349743 hasConceptScore W2613349743C138496976 @default.