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• W2613902570 abstract "Purpose To evaluate the feasibility of quantitative single breath‐hold renal arterial spin labeling (ASL) imaging at 7T. Methods A single‐shot fast spin echo FAIR (flow‐sensitive alternating inversion recovery) method was used to perform two studies. First, a multi‐delay perfusion study was performed to estimate the spin labeling temporal bolus width achievable with a local transceiver array coil at 7T. Second, with a conservatively defined bolus width, a quantitative perfusion study was performed using the single subtraction approach. To address issues of inhomogeneity/efficiency and excessive short‐term specific absorption rates, various strategies were used, such as dynamic radiofrequency shimming and optimization. Results A conservative temporal bolus width of 600 ms determined from the multi‐delay study was applied for single‐subtraction imaging to measure the renal blood flow in the cortex and medulla: 303 ± 31.8 and 91.3 ± 15.2 (mL/100 g/min), respectively. The estimated spatial and temporal signal‐to‐noise ratios of renal perfusion measurements were 3.8 ± 0.7 and 2.4 ± 0.6 for the cortex, and 2.2 ± 0.6 and 1.4 ± 0.2 for the medulla. Conclusion With proper management of field strength specific challenges, quantitative renal ASL imaging can be achieved at 7T within a single breath‐hold. Magn Reson Med 79:815–825, 2018. © 2017 International Society for Magnetic Resonance in Medicine." @default.
• W2613902570 created "2017-05-19" @default.
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• W2613902570 date "2017-05-09" @default.
• W2613902570 modified "2023-10-16" @default.
• W2613902570 title "Quantitative single breath-hold renal arterial spin labeling imaging at 7T" @default.
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• W2613902570 doi "https://doi.org/10.1002/mrm.26742" @default.
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