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- W2614157023 abstract "Abstract Objective To evaluate the role of positron emission tomography combined with computed tomography (PET-CT) in the initial evaluation and response assessment in primary central nervous system lymphoma (PCNSL). Material and method Fourteen patients (8 males) with a median age 59.5 years diagnosed of PCNSL. A brain PET-CT and magnetic resonance imaging (MRI) were performed in the initial evaluation. In 7 patients a PET-CT after treatment was performed. Results PET-CT showed at diagnosis 31 hypermetabolic focuses and MRI showed 47 lesions, with a good grade of concordance between both ( k = 0.61; p = 0.005). In the response assessment, correlation between both techniques was good, and PET-CT was helpful in the appreciation of residual MRI lesions. Overall survival at 2 years of negative vs. positive PET-CT at the end of treatment was 100 vs. 37.5%, respectively ( p = 0.045). Conclusions PET-CT can be useful in the initial evaluation of PCNSL, and especially in the assessment of response. Despite the fact that PET-CT detects less small lesions than MRI, a good correlation between MRI and PET-CT was observed. It is effective in the evaluation of residual lesions. Prospective studies are needed to confirm their possible prognostic value." @default.
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- W2614157023 date "2015-06-01" @default.
- W2614157023 modified "2023-10-07" @default.
- W2614157023 title "Positron emission tomography combined with computed tomography in the initial evaluation and response assessment in primary central nervous system lymphoma" @default.
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- W2614157023 doi "https://doi.org/10.1016/j.medcle.2014.09.005" @default.
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