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- W2614330872 abstract "A simple, fast and green method for chiral recognition of S- and R-naproxen has been introduced. The method was based on quenching of the fluorescence intensity of bovine serum albumin–stabilized gold nanoclusters in the presence of naproxen enantiomers. The quenching intensity in the presence of S-naproxen was higher than R-naproxen when phosphate buffer solution at pH 7.0 was used. The chiral recognition occurred due to steric effect between bovine serum albumin conformation and naproxen enantiomers. Two linear determination range were established as 7.4 × 10−7–9.1 × 10−6 and 9.1 × 10−6–3.1 × 10−5 mol L−1 for both enantiomers and detection limits of 7.4 × 10−8 mol L− 1 and 9.5 × 10−8 mol L−1 were obtained for S- and R-naproxen, respectively. The developed method showed good repeatability and reproducibility for the analysis of a synthetic sample. To make the procedure applicable to biological samples, the removal of heavy metals from the sample is suggested before any analytical attempt." @default.
- W2614330872 created "2017-05-26" @default.
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- W2614330872 date "2017-10-01" @default.
- W2614330872 modified "2023-09-26" @default.
- W2614330872 title "Chiral recognition of naproxen enantiomers based on fluorescence quenching of bovine serum albumin–stabilized gold nanoclusters" @default.
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- W2614330872 doi "https://doi.org/10.1016/j.saa.2017.05.029" @default.
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