Matches in SemOpenAlex for { <https://semopenalex.org/work/W2615262348> ?p ?o ?g. }
- W2615262348 endingPage "721" @default.
- W2615262348 startingPage "715" @default.
- W2615262348 abstract "Aim: Due to the complex nature of Alzheimer's disease, there is a renewed search for multitarget directed drugs. Results: This paper describes the synthesis and in vitro biological evaluation of six racemic 13-aryl-2,3,4,13-tetrahydro-1H,12H-benzo[6,7]chromeno[2,3-d]pyrido[1,2-a]pyrimidine-7,12,14-triones (1a–6a), and six racemic 15-aryl-8,9,10,11,12,15-hexahydro-14H-benzo[6′,7′]chromeno[2′,3:4,5] pyr-imido [1,2-a]azepine-5,14,16-triones (1b–6b), showing antioxidant and cholinesterase inhibitory capacity. Among these compounds, 13-phenyl-2,3,4,13-tetrahydro-1H,12H-benzo[6,7]chromeno[2,3-d]pyrido[1,2-a]pyrimidine-7,12,14-trione (1a) is a nonhepatotoxic at 300 μmol/l dose concentration, and a selective EeAChE inhibitor showing good antioxidant power. Conclusion: A new family of racemic benzochromenopyrimidinetriones has been investigated for their potential use in the treatment of Alzheimer's disease." @default.
- W2615262348 created "2017-05-26" @default.
- W2615262348 creator A5027321643 @default.
- W2615262348 creator A5039672667 @default.
- W2615262348 creator A5041836281 @default.
- W2615262348 creator A5044493452 @default.
- W2615262348 creator A5048368563 @default.
- W2615262348 creator A5080143161 @default.
- W2615262348 creator A5080299713 @default.
- W2615262348 creator A5082905681 @default.
- W2615262348 creator A5084469840 @default.
- W2615262348 date "2017-05-01" @default.
- W2615262348 modified "2023-09-26" @default.
- W2615262348 title "Synthesis and biological assessment of racemic benzochromenopyrimidinetriones as promising agents for Alzheimer's disease therapy" @default.
- W2615262348 cites W1629179716 @default.
- W2615262348 cites W1940331911 @default.
- W2615262348 cites W1965315991 @default.
- W2615262348 cites W1965910452 @default.
- W2615262348 cites W1971048984 @default.
- W2615262348 cites W1981775239 @default.
- W2615262348 cites W1982847857 @default.
- W2615262348 cites W2000837493 @default.
- W2615262348 cites W2003715018 @default.
- W2615262348 cites W2004713321 @default.
- W2615262348 cites W2006656242 @default.
- W2615262348 cites W2013176372 @default.
- W2615262348 cites W2019608356 @default.
- W2615262348 cites W2036755018 @default.
- W2615262348 cites W2038003980 @default.
- W2615262348 cites W2039069312 @default.
- W2615262348 cites W2039402692 @default.
- W2615262348 cites W2041818036 @default.
- W2615262348 cites W2044632501 @default.
- W2615262348 cites W2048510686 @default.
- W2615262348 cites W2057434602 @default.
- W2615262348 cites W2071180837 @default.
- W2615262348 cites W2072219894 @default.
- W2615262348 cites W2076854979 @default.
- W2615262348 cites W2093979148 @default.
- W2615262348 cites W2105259065 @default.
- W2615262348 cites W2121322934 @default.
- W2615262348 cites W2124362440 @default.
- W2615262348 cites W2126866334 @default.
- W2615262348 cites W2135732933 @default.
- W2615262348 cites W2252542094 @default.
- W2615262348 cites W2289453788 @default.
- W2615262348 cites W2386192302 @default.
- W2615262348 cites W2398548303 @default.
- W2615262348 cites W2554115926 @default.
- W2615262348 cites W2951308643 @default.
- W2615262348 cites W4211208097 @default.
- W2615262348 cites W883464414 @default.
- W2615262348 doi "https://doi.org/10.4155/fmc-2017-0004" @default.
- W2615262348 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28504912" @default.
- W2615262348 hasPublicationYear "2017" @default.
- W2615262348 type Work @default.
- W2615262348 sameAs 2615262348 @default.
- W2615262348 citedByCount "10" @default.
- W2615262348 countsByYear W26152623482017 @default.
- W2615262348 countsByYear W26152623482018 @default.
- W2615262348 countsByYear W26152623482019 @default.
- W2615262348 countsByYear W26152623482020 @default.
- W2615262348 countsByYear W26152623482021 @default.
- W2615262348 countsByYear W26152623482022 @default.
- W2615262348 countsByYear W26152623482023 @default.
- W2615262348 crossrefType "journal-article" @default.
- W2615262348 hasAuthorship W2615262348A5027321643 @default.
- W2615262348 hasAuthorship W2615262348A5039672667 @default.
- W2615262348 hasAuthorship W2615262348A5041836281 @default.
- W2615262348 hasAuthorship W2615262348A5044493452 @default.
- W2615262348 hasAuthorship W2615262348A5048368563 @default.
- W2615262348 hasAuthorship W2615262348A5080143161 @default.
- W2615262348 hasAuthorship W2615262348A5080299713 @default.
- W2615262348 hasAuthorship W2615262348A5082905681 @default.
- W2615262348 hasAuthorship W2615262348A5084469840 @default.
- W2615262348 hasConcept C178790620 @default.
- W2615262348 hasConcept C185592680 @default.
- W2615262348 hasConcept C202751555 @default.
- W2615262348 hasConcept C2777752497 @default.
- W2615262348 hasConcept C2778004101 @default.
- W2615262348 hasConcept C2779321679 @default.
- W2615262348 hasConcept C2780263894 @default.
- W2615262348 hasConcept C2781076698 @default.
- W2615262348 hasConcept C31896038 @default.
- W2615262348 hasConcept C55493867 @default.
- W2615262348 hasConcept C71240020 @default.
- W2615262348 hasConcept C71924100 @default.
- W2615262348 hasConcept C98274493 @default.
- W2615262348 hasConceptScore W2615262348C178790620 @default.
- W2615262348 hasConceptScore W2615262348C185592680 @default.
- W2615262348 hasConceptScore W2615262348C202751555 @default.
- W2615262348 hasConceptScore W2615262348C2777752497 @default.
- W2615262348 hasConceptScore W2615262348C2778004101 @default.
- W2615262348 hasConceptScore W2615262348C2779321679 @default.
- W2615262348 hasConceptScore W2615262348C2780263894 @default.
- W2615262348 hasConceptScore W2615262348C2781076698 @default.
- W2615262348 hasConceptScore W2615262348C31896038 @default.
- W2615262348 hasConceptScore W2615262348C55493867 @default.