FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2615647870> ?p ?o ?g. }

• W2615647870 endingPage "161" @default.
• W2615647870 startingPage "151" @default.
• W2615647870 abstract "Amyloids and amyloid-based prions are self-perpetuating protein aggregates which can spread by converting a normal protein of the same sequence into a prion form. They are associated with diseases in humans and mammals, and control heritable traits in yeast and other fungi. Some amyloids are implicated in biologically beneficial processes. As prion formation generates reproducible memory of a conformational change, prions can be considered as molecular memory devices. We have demonstrated that in yeast, stress-inducible cytoskeleton-associated protein Lsb2 forms a metastable prion in response to high temperature. This prion promotes conversion of other proteins into prions and can persist in a fraction of cells for a significant number of cell generations after stress, thus maintaining the memory of stress in a population of surviving cells. Acquisition of an amino acid substitution required for Lsb2 to form a prion coincides with acquisition of increased thermotolerance in the evolution of Saccharomyces yeast. Thus the ability to form an Lsb2 prion in response to stress coincides with yeast adaptation to growth at higher temperatures. These findings intimately connect prion formation to the cellular response to environmental stresses." @default.
• W2615647870 created "2017-05-26" @default.
• W2615647870 creator A5068814839 @default.
• W2615647870 creator A5072493494 @default.
• W2615647870 creator A5082912822 @default.
• W2615647870 date "2017-05-04" @default.
• W2615647870 modified "2023-09-28" @default.
• W2615647870 title "Prion-based memory of heat stress in yeast" @default.
• W2615647870 cites W1487311594 @default.
• W2615647870 cites W1499922418 @default.
• W2615647870 cites W1604910734 @default.
• W2615647870 cites W1857855090 @default.
• W2615647870 cites W1872122 @default.
• W2615647870 cites W1905375199 @default.
• W2615647870 cites W1926513104 @default.
• W2615647870 cites W1939575473 @default.
• W2615647870 cites W1976201852 @default.
• W2615647870 cites W1977796112 @default.
• W2615647870 cites W1978959047 @default.
• W2615647870 cites W1980675329 @default.
• W2615647870 cites W1986118996 @default.
• W2615647870 cites W1987327305 @default.
• W2615647870 cites W1988561224 @default.
• W2615647870 cites W1990365848 @default.
• W2615647870 cites W1993513091 @default.
• W2615647870 cites W1994235379 @default.
• W2615647870 cites W1999306718 @default.
• W2615647870 cites W1999886226 @default.
• W2615647870 cites W2000204824 @default.
• W2615647870 cites W2001498689 @default.
• W2615647870 cites W2006952692 @default.
• W2615647870 cites W2008217034 @default.
• W2615647870 cites W2009568691 @default.
• W2615647870 cites W2012223842 @default.
• W2615647870 cites W2016754171 @default.
• W2615647870 cites W2018852249 @default.
• W2615647870 cites W2018902287 @default.
• W2615647870 cites W2028728539 @default.
• W2615647870 cites W2032015542 @default.
• W2615647870 cites W2034325842 @default.
• W2615647870 cites W2036735052 @default.
• W2615647870 cites W2039329450 @default.
• W2615647870 cites W2043676526 @default.
• W2615647870 cites W2044061340 @default.
• W2615647870 cites W2044143909 @default.
• W2615647870 cites W2046093999 @default.
• W2615647870 cites W2048528317 @default.
• W2615647870 cites W2050586659 @default.
• W2615647870 cites W2052228596 @default.
• W2615647870 cites W2054393791 @default.
• W2615647870 cites W2065722011 @default.
• W2615647870 cites W2067682626 @default.
• W2615647870 cites W2071069041 @default.
• W2615647870 cites W2072206310 @default.
• W2615647870 cites W2076713412 @default.
• W2615647870 cites W2078771540 @default.
• W2615647870 cites W2081726283 @default.
• W2615647870 cites W2082429191 @default.
• W2615647870 cites W2086991973 @default.
• W2615647870 cites W2088511593 @default.
• W2615647870 cites W2088714061 @default.
• W2615647870 cites W2092845029 @default.
• W2615647870 cites W2096410114 @default.
• W2615647870 cites W2105148157 @default.
• W2615647870 cites W2106046434 @default.
• W2615647870 cites W2110398521 @default.
• W2615647870 cites W2111456013 @default.
• W2615647870 cites W2119651404 @default.
• W2615647870 cites W2131286471 @default.
• W2615647870 cites W2136679442 @default.
• W2615647870 cites W2138893131 @default.
• W2615647870 cites W2138906088 @default.
• W2615647870 cites W2150555206 @default.
• W2615647870 cites W2154242305 @default.
• W2615647870 cites W2166699835 @default.
• W2615647870 cites W2169665392 @default.
• W2615647870 cites W2504884251 @default.
• W2615647870 cites W2532726012 @default.
• W2615647870 cites W2547881573 @default.
• W2615647870 cites W2567962298 @default.
• W2615647870 cites W2577386528 @default.
• W2615647870 cites W2769003964 @default.
• W2615647870 cites W4211121722 @default.
• W2615647870 cites W54590555 @default.
• W2615647870 doi "https://doi.org/10.1080/19336896.2017.1328342" @default.
• W2615647870 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5480388" @default.
• W2615647870 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28521568" @default.
• W2615647870 hasPublicationYear "2017" @default.
• W2615647870 type Work @default.
• W2615647870 sameAs 2615647870 @default.
• W2615647870 citedByCount "20" @default.
• W2615647870 countsByYear W26156478702018 @default.
• W2615647870 countsByYear W26156478702019 @default.
• W2615647870 countsByYear W26156478702020 @default.
• W2615647870 countsByYear W26156478702021 @default.
• W2615647870 countsByYear W26156478702022 @default.
• W2615647870 countsByYear W26156478702023 @default.
• W2615647870 crossrefType "journal-article" @default.

• next