Matches in SemOpenAlex for { <https://semopenalex.org/work/W2615708966> ?p ?o ?g. }
- W2615708966 endingPage "1472" @default.
- W2615708966 startingPage "1465" @default.
- W2615708966 abstract "ObjectivesInitial data on drug-eluting stents (DES) shows that they may increase the durability of endovascular treatment of superficial femoral artery disease compared with traditional bare-metal stents (BMS). Observed decreased target lesion revascularization (TLR) rates have potential for cost savings despite an increased initial cost. The purpose of this study was to run a simulation model of progressive transition from BMS to DES over 5 years evaluating the overall cost impact of that transition.MethodsFlorida State Ambulatory Databases were searched for all patients undergoing superficial femoral artery stenting in 2013 using Current Procedural Terminology codes 37226 and 37227. A simulation model was developed to estimate the impact of a progressive transition from BMS to DES over a 5-year horizon in this patient population. Cost estimates were determined from available cost charge ratio data. For the 5-year model, 2013 served as the initial year with each subsequent year based on the expected number of interventions per year. Up to one TLR per patient was assumed for the model. The 5-year TLR rates for DES and other parameter estimates were based on pooled data from the literature. Institutional data were used to estimate that up to 48% of superficial femoral artery lesions would fit the instructions for use for the Zilver PTX (Cook Medical, Bloomington, Ind), which is currently the only DES approved by the U.S. Food and Drug Administration for peripheral interventions. The net budget impact was expressed as the difference in total costs (primary stenting and reinterventions) for a scenario where BMS is progressively replaced by Zilver PTX compared with a scenario of BMS only. Multiple sensitivity analyses were performed on the base scenario.ResultsWe identified 4107 peripheral interventions in the first year that fit our study. The overall cost for these procedures in Florida database was $51,362,142.00. In the base case scenario, DES was introduced slowly into the population at a rate of 8% per year up to 48% at the end of the model. This strategy resulted in an overall cost savings of $1,688,953.72 compared with the model with BMS alone. Sensitivity analyses including slower adoption of DES up to only 24% at 5 years, a 20% increase in TLR rates per year for the DES, and a 10% reduction in TLR rates per year for BMS still resulted in a net savings. As long as the additional cost of a DES compared with BMS is less than $677, the DES model remains less expensive.ConclusionsThe adoption of DES in lieu of traditional BMS can lead to significant cost savings in a single state model over a short time horizon." @default.
- W2615708966 created "2017-05-26" @default.
- W2615708966 creator A5000622050 @default.
- W2615708966 creator A5001794232 @default.
- W2615708966 creator A5005475364 @default.
- W2615708966 creator A5018957850 @default.
- W2615708966 creator A5021911875 @default.
- W2615708966 creator A5039147795 @default.
- W2615708966 creator A5040811140 @default.
- W2615708966 creator A5072920508 @default.
- W2615708966 date "2018-11-01" @default.
- W2615708966 modified "2023-09-30" @default.
- W2615708966 title "Implementation of drug-eluting stents for the treatment of femoropopliteal disease provides significant cost-to-system savings in a single-state outpatient simulation" @default.
- W2615708966 cites W114852567 @default.
- W2615708966 cites W1495593727 @default.
- W2615708966 cites W1886679205 @default.
- W2615708966 cites W1931807903 @default.
- W2615708966 cites W1998483781 @default.
- W2615708966 cites W2000137078 @default.
- W2615708966 cites W2126502186 @default.
- W2615708966 cites W2145600607 @default.
- W2615708966 cites W2171923126 @default.
- W2615708966 cites W2185467918 @default.
- W2615708966 cites W2282902382 @default.
- W2615708966 cites W2295508527 @default.
- W2615708966 cites W2337206574 @default.
- W2615708966 cites W2338860418 @default.
- W2615708966 cites W2347152092 @default.
- W2615708966 cites W2472900203 @default.
- W2615708966 cites W2507218801 @default.
- W2615708966 cites W2887208783 @default.
- W2615708966 cites W58145282 @default.
- W2615708966 cites W94442196 @default.
- W2615708966 cites W956910018 @default.
- W2615708966 doi "https://doi.org/10.1016/j.jvs.2018.02.040" @default.
- W2615708966 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6394222" @default.
- W2615708966 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29779962" @default.
- W2615708966 hasPublicationYear "2018" @default.
- W2615708966 type Work @default.
- W2615708966 sameAs 2615708966 @default.
- W2615708966 citedByCount "5" @default.
- W2615708966 countsByYear W26157089662021 @default.
- W2615708966 countsByYear W26157089662022 @default.
- W2615708966 countsByYear W26157089662023 @default.
- W2615708966 crossrefType "journal-article" @default.
- W2615708966 hasAuthorship W2615708966A5000622050 @default.
- W2615708966 hasAuthorship W2615708966A5001794232 @default.
- W2615708966 hasAuthorship W2615708966A5005475364 @default.
- W2615708966 hasAuthorship W2615708966A5018957850 @default.
- W2615708966 hasAuthorship W2615708966A5021911875 @default.
- W2615708966 hasAuthorship W2615708966A5039147795 @default.
- W2615708966 hasAuthorship W2615708966A5040811140 @default.
- W2615708966 hasAuthorship W2615708966A5072920508 @default.
- W2615708966 hasBestOaLocation W26157089661 @default.
- W2615708966 hasConcept C118552586 @default.
- W2615708966 hasConcept C126322002 @default.
- W2615708966 hasConcept C141071460 @default.
- W2615708966 hasConcept C27415008 @default.
- W2615708966 hasConcept C2777546689 @default.
- W2615708966 hasConcept C2778283817 @default.
- W2615708966 hasConcept C2778583881 @default.
- W2615708966 hasConcept C2779464278 @default.
- W2615708966 hasConcept C2779513377 @default.
- W2615708966 hasConcept C2908647359 @default.
- W2615708966 hasConcept C35785553 @default.
- W2615708966 hasConcept C500558357 @default.
- W2615708966 hasConcept C71924100 @default.
- W2615708966 hasConcept C99454951 @default.
- W2615708966 hasConceptScore W2615708966C118552586 @default.
- W2615708966 hasConceptScore W2615708966C126322002 @default.
- W2615708966 hasConceptScore W2615708966C141071460 @default.
- W2615708966 hasConceptScore W2615708966C27415008 @default.
- W2615708966 hasConceptScore W2615708966C2777546689 @default.
- W2615708966 hasConceptScore W2615708966C2778283817 @default.
- W2615708966 hasConceptScore W2615708966C2778583881 @default.
- W2615708966 hasConceptScore W2615708966C2779464278 @default.
- W2615708966 hasConceptScore W2615708966C2779513377 @default.
- W2615708966 hasConceptScore W2615708966C2908647359 @default.
- W2615708966 hasConceptScore W2615708966C35785553 @default.
- W2615708966 hasConceptScore W2615708966C500558357 @default.
- W2615708966 hasConceptScore W2615708966C71924100 @default.
- W2615708966 hasConceptScore W2615708966C99454951 @default.
- W2615708966 hasIssue "5" @default.
- W2615708966 hasLocation W26157089661 @default.
- W2615708966 hasLocation W26157089662 @default.
- W2615708966 hasLocation W26157089663 @default.
- W2615708966 hasLocation W26157089664 @default.
- W2615708966 hasOpenAccess W2615708966 @default.
- W2615708966 hasPrimaryLocation W26157089661 @default.
- W2615708966 hasRelatedWork W1976994629 @default.
- W2615708966 hasRelatedWork W2015473457 @default.
- W2615708966 hasRelatedWork W2382588851 @default.
- W2615708966 hasRelatedWork W2390890898 @default.
- W2615708966 hasRelatedWork W2396790956 @default.
- W2615708966 hasRelatedWork W2418555350 @default.
- W2615708966 hasRelatedWork W2921830237 @default.
- W2615708966 hasRelatedWork W2967086639 @default.
- W2615708966 hasRelatedWork W2978746237 @default.