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- W26159997 abstract "No AccessJournal of Urology1 May 1987Urothelial Leukoplakia: New Aspects of Etiology and Therapy S.C. Mueller, J.W. Thueroff, and H.J. Rumpelt S.C. MuellerS.C. Mueller More articles by this author , J.W. ThueroffJ.W. Thueroff More articles by this author , and H.J. RumpeltH.J. Rumpelt More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)44322-9AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail We describe 3 women in 1 family who had systemic urothelial leukoplakia with no underlying pathological condition of the urinary tract. Irritative clinical symptoms resolved, and the macroscopic and microscopic appearance improved after 6 months of therapy with sodium pentosan-polysulfate. Electron microscopy showed special cells in the basal layer of the cornified squamous epithelium that also have been found in the trigone of women with so-called squamous metaplasia. Their similarity to Merkel’s cells of the skin supports the theory that ectodermal cells are misplaced during embryogenesis. Genetic factors and sex hormones seem to influence the development of certain variants of squamous epithelium within the urinary tract. © 1987 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 137Issue 5May 1987Page: 979-983 Advertisement Copyright & Permissions© 1987 by The American Urological Association Education and Research, Inc.MetricsAuthor Information S.C. Mueller More articles by this author J.W. Thueroff More articles by this author H.J. Rumpelt More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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- W26159997 date "1987-05-01" @default.
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- W26159997 title "Urothelial Leukoplakia: New Aspects of Etiology and Therapy" @default.
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