Matches in SemOpenAlex for { <https://semopenalex.org/work/W2616012014> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2616012014 abstract "Background/Aims: Sarcoidosis is a multiorgan granulomatous inflammatory disease of an unknown cause, probably due to inappropriate T-cell response. Mutation in BTNL2 gene (Butirophylin-like2) which is one of the most important genes in MHC II (complex tissue incompatibility) group is related to sarcoidosis. Our purpose was to evaluate BTNL2 rs2076530 G/A allele as a putative genetic for sarcoidosis in an Iranian population.Methods: DNA from patients and controls was obtained from peripheral blood using standard methods. 490-bp amplicon of each samples were genotyped for the BTNL2 G → A transition of rs2076530 using an ABI 3130 automated sequencer-Big-Dye Terminator Version 3.1 Cycle.Results: A total of 50 patients with sarcoidosis were registered in our study of which 33 were females (66%) and 17 were male (34%). 26 women (52% total) and 14 men (28% of total) showed SNP mutation in Exon/Intron 5 of the BTNL2 gene (P Value<0.001). In these groups of patients, 40 (80%) had G to A transition at rs2076530 allele and 10 patients (20%) didn't have the mutation. 40 control samples were checked as control and all of them were normal for this allele.Conclusion: Our findings in clinical and also genetically, indicates that rs2076530 allele is a high risk criterion in Iranian sarcoidosis." @default.
- W2616012014 created "2017-05-26" @default.
- W2616012014 creator A5005328255 @default.
- W2616012014 creator A5026292970 @default.
- W2616012014 creator A5064758964 @default.
- W2616012014 creator A5069525910 @default.
- W2616012014 creator A5074589230 @default.
- W2616012014 creator A5074612170 @default.
- W2616012014 creator A5084377032 @default.
- W2616012014 date "2017-01-01" @default.
- W2616012014 modified "2023-09-26" @default.
- W2616012014 title "Detection of BTNL2 Gene Mutation (rs2076530 Allele) in Iranian Sarcoidosis Patients: A clinical and Genetic Study" @default.
- W2616012014 cites W1423113081 @default.
- W2616012014 cites W165412877 @default.
- W2616012014 cites W171721334 @default.
- W2616012014 cites W1991360777 @default.
- W2616012014 cites W1995254015 @default.
- W2616012014 cites W2018202283 @default.
- W2616012014 cites W2034861538 @default.
- W2616012014 cites W2043412809 @default.
- W2616012014 cites W2094338449 @default.
- W2616012014 cites W2097605211 @default.
- W2616012014 cites W2100288258 @default.
- W2616012014 cites W2109465510 @default.
- W2616012014 cites W2114212701 @default.
- W2616012014 cites W2123558802 @default.
- W2616012014 doi "https://doi.org/10.4172/2165-8048.1000239" @default.
- W2616012014 hasPublicationYear "2017" @default.
- W2616012014 type Work @default.
- W2616012014 sameAs 2616012014 @default.
- W2616012014 citedByCount "0" @default.
- W2616012014 crossrefType "journal-article" @default.
- W2616012014 hasAuthorship W2616012014A5005328255 @default.
- W2616012014 hasAuthorship W2616012014A5026292970 @default.
- W2616012014 hasAuthorship W2616012014A5064758964 @default.
- W2616012014 hasAuthorship W2616012014A5069525910 @default.
- W2616012014 hasAuthorship W2616012014A5074589230 @default.
- W2616012014 hasAuthorship W2616012014A5074612170 @default.
- W2616012014 hasAuthorship W2616012014A5084377032 @default.
- W2616012014 hasBestOaLocation W26160120141 @default.
- W2616012014 hasConcept C104317684 @default.
- W2616012014 hasConcept C126322002 @default.
- W2616012014 hasConcept C180754005 @default.
- W2616012014 hasConcept C203014093 @default.
- W2616012014 hasConcept C2781301800 @default.
- W2616012014 hasConcept C2908647359 @default.
- W2616012014 hasConcept C37463918 @default.
- W2616012014 hasConcept C54355233 @default.
- W2616012014 hasConcept C71924100 @default.
- W2616012014 hasConcept C86803240 @default.
- W2616012014 hasConcept C99454951 @default.
- W2616012014 hasConceptScore W2616012014C104317684 @default.
- W2616012014 hasConceptScore W2616012014C126322002 @default.
- W2616012014 hasConceptScore W2616012014C180754005 @default.
- W2616012014 hasConceptScore W2616012014C203014093 @default.
- W2616012014 hasConceptScore W2616012014C2781301800 @default.
- W2616012014 hasConceptScore W2616012014C2908647359 @default.
- W2616012014 hasConceptScore W2616012014C37463918 @default.
- W2616012014 hasConceptScore W2616012014C54355233 @default.
- W2616012014 hasConceptScore W2616012014C71924100 @default.
- W2616012014 hasConceptScore W2616012014C86803240 @default.
- W2616012014 hasConceptScore W2616012014C99454951 @default.
- W2616012014 hasIssue "02" @default.
- W2616012014 hasLocation W26160120141 @default.
- W2616012014 hasOpenAccess W2616012014 @default.
- W2616012014 hasPrimaryLocation W26160120141 @default.
- W2616012014 hasRelatedWork W1821101056 @default.
- W2616012014 hasRelatedWork W1965878248 @default.
- W2616012014 hasRelatedWork W1986071932 @default.
- W2616012014 hasRelatedWork W2000894249 @default.
- W2616012014 hasRelatedWork W2001411647 @default.
- W2616012014 hasRelatedWork W2002416157 @default.
- W2616012014 hasRelatedWork W2048610425 @default.
- W2616012014 hasRelatedWork W2059569464 @default.
- W2616012014 hasRelatedWork W2059741124 @default.
- W2616012014 hasRelatedWork W2077228668 @default.
- W2616012014 hasRelatedWork W2107179569 @default.
- W2616012014 hasRelatedWork W2107376246 @default.
- W2616012014 hasRelatedWork W2113753326 @default.
- W2616012014 hasRelatedWork W2117105832 @default.
- W2616012014 hasRelatedWork W2127218534 @default.
- W2616012014 hasRelatedWork W2351888590 @default.
- W2616012014 hasRelatedWork W2380460553 @default.
- W2616012014 hasRelatedWork W2382451317 @default.
- W2616012014 hasRelatedWork W2393553026 @default.
- W2616012014 hasRelatedWork W166751502 @default.
- W2616012014 hasVolume "07" @default.
- W2616012014 isParatext "false" @default.
- W2616012014 isRetracted "false" @default.
- W2616012014 magId "2616012014" @default.
- W2616012014 workType "article" @default.