FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2616036405> ?p ?o ?g. }

• W2616036405 abstract "Risk prediction algorithms increase understanding of which patients are at greatest risk of a harmful outcome. Our goal was to create a clinically useful prediction algorithm for structural progression of knee osteoarthritis (OA), using medial joint space loss as a proxy; and to quantify the benefit of including periarticular bone mineral density (BMD) in the algorithm. Participants were from the Osteoarthritis Initiative (OAI) Progression Cohort, with X-ray readings of medial joint space at 36- and 48-month visits, and a 30- or 36-month medial-to-lateral tibial BMD ratio (M:L BMD ratio) value. Loss of medial joint space was the outcome and clinically available factors associated with OA progression were employed in the base prediction algorithm, with M:L BMD ratio added to an enhanced prediction algorithm. The benefit of adding M:L BMD ratio was evaluated by change in area under the ROC curve (AUC), net reclassification improvement (NRI), and integrated discrimination improvement (IDI). Five hundred thirty-three participants were included; 51 (14%) had medial joint space loss; 47% were female; the mean (SD) age was 64.6 (9.2) years and BMI was 29.6 (4.8) kg/m2. The base algorithm model included age, BMI, gender, recent injury, knee pain, and hand OA as predictors and had an AUC value of 0.65. The algorithm adding M:L BMD ratio had an AUC value of 0.73, and the AUC, NRI and IDI were all significantly improved (p ≤ 0.002). This clinical prediction algorithm predicts structural progression in individuals with OA using only clinically available predictors supplemented by the M:L BMD ratio, a biomarker that could be made available at clinical sites." @default.
• W2616036405 created "2017-05-26" @default.
• W2616036405 creator A5007363152 @default.
• W2616036405 creator A5027529514 @default.
• W2616036405 creator A5041756550 @default.
• W2616036405 creator A5045583989 @default.
• W2616036405 creator A5047366011 @default.
• W2616036405 creator A5085745764 @default.
• W2616036405 date "2017-05-16" @default.
• W2616036405 modified "2023-10-06" @default.
• W2616036405 title "Development of a clinical prediction algorithm for knee osteoarthritis structural progression in a cohort study: value of adding measurement of subchondral bone density" @default.
• W2616036405 cites W131970863 @default.
• W2616036405 cites W1480376833 @default.
• W2616036405 cites W1941342725 @default.
• W2616036405 cites W1967057044 @default.
• W2616036405 cites W1968493980 @default.
• W2616036405 cites W1974759500 @default.
• W2616036405 cites W1983428717 @default.
• W2616036405 cites W1997140718 @default.
• W2616036405 cites W1997637714 @default.
• W2616036405 cites W2000404603 @default.
• W2616036405 cites W2001299659 @default.
• W2616036405 cites W2008305894 @default.
• W2616036405 cites W2013904927 @default.
• W2616036405 cites W2019739615 @default.
• W2616036405 cites W2032306447 @default.
• W2616036405 cites W2037668591 @default.
• W2616036405 cites W2038484287 @default.
• W2616036405 cites W2042196436 @default.
• W2616036405 cites W2042679348 @default.
• W2616036405 cites W2043987752 @default.
• W2616036405 cites W2044655214 @default.
• W2616036405 cites W2045039571 @default.
• W2616036405 cites W2066505316 @default.
• W2616036405 cites W2068305673 @default.
• W2616036405 cites W2076963888 @default.
• W2616036405 cites W2086938649 @default.
• W2616036405 cites W2088995642 @default.
• W2616036405 cites W2096019949 @default.
• W2616036405 cites W2104268311 @default.
• W2616036405 cites W2106421416 @default.
• W2616036405 cites W2118529444 @default.
• W2616036405 cites W2118567612 @default.
• W2616036405 cites W2121144887 @default.
• W2616036405 cites W2136673759 @default.
• W2616036405 cites W2140012387 @default.
• W2616036405 cites W2144278887 @default.
• W2616036405 cites W2154286581 @default.
• W2616036405 cites W2605975631 @default.
• W2616036405 cites W3175417087 @default.
• W2616036405 cites W4299689471 @default.
• W2616036405 doi "https://doi.org/10.1186/s13075-017-1291-3" @default.
• W2616036405 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5433155" @default.
• W2616036405 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28511690" @default.
• W2616036405 hasPublicationYear "2017" @default.
• W2616036405 type Work @default.
• W2616036405 sameAs 2616036405 @default.
• W2616036405 citedByCount "32" @default.
• W2616036405 countsByYear W26160364052018 @default.
• W2616036405 countsByYear W26160364052019 @default.
• W2616036405 countsByYear W26160364052020 @default.
• W2616036405 countsByYear W26160364052021 @default.
• W2616036405 countsByYear W26160364052022 @default.
• W2616036405 countsByYear W26160364052023 @default.
• W2616036405 crossrefType "journal-article" @default.
• W2616036405 hasAuthorship W2616036405A5007363152 @default.
• W2616036405 hasAuthorship W2616036405A5027529514 @default.
• W2616036405 hasAuthorship W2616036405A5041756550 @default.
• W2616036405 hasAuthorship W2616036405A5045583989 @default.
• W2616036405 hasAuthorship W2616036405A5047366011 @default.
• W2616036405 hasAuthorship W2616036405A5085745764 @default.
• W2616036405 hasBestOaLocation W26160364051 @default.
• W2616036405 hasConcept C11413529 @default.
• W2616036405 hasConcept C126322002 @default.
• W2616036405 hasConcept C142724271 @default.
• W2616036405 hasConcept C1862650 @default.
• W2616036405 hasConcept C198451711 @default.
• W2616036405 hasConcept C204787440 @default.
• W2616036405 hasConcept C2776164576 @default.
• W2616036405 hasConcept C2776541429 @default.
• W2616036405 hasConcept C2776886416 @default.
• W2616036405 hasConcept C33923547 @default.
• W2616036405 hasConcept C71924100 @default.
• W2616036405 hasConcept C72563966 @default.
• W2616036405 hasConceptScore W2616036405C11413529 @default.
• W2616036405 hasConceptScore W2616036405C126322002 @default.
• W2616036405 hasConceptScore W2616036405C142724271 @default.
• W2616036405 hasConceptScore W2616036405C1862650 @default.
• W2616036405 hasConceptScore W2616036405C198451711 @default.
• W2616036405 hasConceptScore W2616036405C204787440 @default.
• W2616036405 hasConceptScore W2616036405C2776164576 @default.
• W2616036405 hasConceptScore W2616036405C2776541429 @default.
• W2616036405 hasConceptScore W2616036405C2776886416 @default.
• W2616036405 hasConceptScore W2616036405C33923547 @default.
• W2616036405 hasConceptScore W2616036405C71924100 @default.
• W2616036405 hasConceptScore W2616036405C72563966 @default.
• W2616036405 hasFunder F4320332161 @default.
• W2616036405 hasIssue "1" @default.
• W2616036405 hasLocation W26160364051 @default.
• W2616036405 hasLocation W26160364052 @default.

• next