Matches in SemOpenAlex for { <https://semopenalex.org/work/W2616134920> ?p ?o ?g. }
- W2616134920 abstract "Abstract The low in vivo survival rate of scaffold-seeded cells is still a challenge in stem cell-based bone regeneration. This study seeks to use a silk hydrogel to deliver more stem cells into a bone defect area and prolong the viability of these cells after implantation. Rat bone marrow stem cells were mingled with silk hydrogels at the concentrations of 1.0 × 10 5 /mL, 1.0 × 10 6 /mL and 1.0 × 10 7 /mL before gelation, added dropwise to a silk scaffold and applied to a rat calvarial defect. A cell tracing experiment was included to observe the preservation of cell viability and function. The results show that the hydrogel with 1.0 × 10 7 /mL stem cells exhibited the best osteogenic effect both in vitro and in vivo . The cell-tracing experiment shows that cells in the 1.0 × 10 7 group still survive and actively participate in new bone formation 8 weeks after implantation. The strategy of pre-mingling stem cells with the hydrogel had the effect of delivering more stem cells for bone engineering while preserving the viability and functions of these cells in vivo ." @default.
- W2616134920 created "2017-05-26" @default.
- W2616134920 creator A5005522080 @default.
- W2616134920 creator A5006533811 @default.
- W2616134920 creator A5042610567 @default.
- W2616134920 creator A5057560640 @default.
- W2616134920 creator A5057871048 @default.
- W2616134920 creator A5079153511 @default.
- W2616134920 creator A5083372778 @default.
- W2616134920 date "2017-05-19" @default.
- W2616134920 modified "2023-10-18" @default.
- W2616134920 title "Increased stem cells delivered using a silk gel/scaffold complex for enhanced bone regeneration" @default.
- W2616134920 cites W1129870622 @default.
- W2616134920 cites W1488563510 @default.
- W2616134920 cites W1944598815 @default.
- W2616134920 cites W1968509653 @default.
- W2616134920 cites W1972570419 @default.
- W2616134920 cites W1977704636 @default.
- W2616134920 cites W1981539504 @default.
- W2616134920 cites W198503490 @default.
- W2616134920 cites W1988510537 @default.
- W2616134920 cites W1992781478 @default.
- W2616134920 cites W2003433953 @default.
- W2616134920 cites W2004982583 @default.
- W2616134920 cites W2023840761 @default.
- W2616134920 cites W2028153000 @default.
- W2616134920 cites W2028294279 @default.
- W2616134920 cites W2033142715 @default.
- W2616134920 cites W2036122797 @default.
- W2616134920 cites W2038328829 @default.
- W2616134920 cites W2038987199 @default.
- W2616134920 cites W2049799550 @default.
- W2616134920 cites W2054988877 @default.
- W2616134920 cites W2056168448 @default.
- W2616134920 cites W2057655280 @default.
- W2616134920 cites W2058393114 @default.
- W2616134920 cites W2064462897 @default.
- W2616134920 cites W2064707228 @default.
- W2616134920 cites W2065961219 @default.
- W2616134920 cites W2067844178 @default.
- W2616134920 cites W2071816516 @default.
- W2616134920 cites W2076828256 @default.
- W2616134920 cites W2077648724 @default.
- W2616134920 cites W2077990286 @default.
- W2616134920 cites W2080523658 @default.
- W2616134920 cites W2080644989 @default.
- W2616134920 cites W2083501789 @default.
- W2616134920 cites W2084610464 @default.
- W2616134920 cites W2091107068 @default.
- W2616134920 cites W2093396518 @default.
- W2616134920 cites W2110765265 @default.
- W2616134920 cites W2131943899 @default.
- W2616134920 cites W2134888071 @default.
- W2616134920 cites W2152621785 @default.
- W2616134920 cites W2157908104 @default.
- W2616134920 cites W2169220536 @default.
- W2616134920 cites W2177526066 @default.
- W2616134920 cites W2298497615 @default.
- W2616134920 cites W2309012093 @default.
- W2616134920 cites W2341540989 @default.
- W2616134920 cites W2509648701 @default.
- W2616134920 cites W2559081809 @default.
- W2616134920 cites W2581486461 @default.
- W2616134920 doi "https://doi.org/10.1038/s41598-017-02053-z" @default.
- W2616134920 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5438390" @default.
- W2616134920 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28526887" @default.
- W2616134920 hasPublicationYear "2017" @default.
- W2616134920 type Work @default.
- W2616134920 sameAs 2616134920 @default.
- W2616134920 citedByCount "19" @default.
- W2616134920 countsByYear W26161349202018 @default.
- W2616134920 countsByYear W26161349202019 @default.
- W2616134920 countsByYear W26161349202020 @default.
- W2616134920 countsByYear W26161349202021 @default.
- W2616134920 countsByYear W26161349202022 @default.
- W2616134920 countsByYear W26161349202023 @default.
- W2616134920 crossrefType "journal-article" @default.
- W2616134920 hasAuthorship W2616134920A5005522080 @default.
- W2616134920 hasAuthorship W2616134920A5006533811 @default.
- W2616134920 hasAuthorship W2616134920A5042610567 @default.
- W2616134920 hasAuthorship W2616134920A5057560640 @default.
- W2616134920 hasAuthorship W2616134920A5057871048 @default.
- W2616134920 hasAuthorship W2616134920A5079153511 @default.
- W2616134920 hasAuthorship W2616134920A5083372778 @default.
- W2616134920 hasBestOaLocation W26161349201 @default.
- W2616134920 hasConcept C108586683 @default.
- W2616134920 hasConcept C136229726 @default.
- W2616134920 hasConcept C150903083 @default.
- W2616134920 hasConcept C159985019 @default.
- W2616134920 hasConcept C171056886 @default.
- W2616134920 hasConcept C178790620 @default.
- W2616134920 hasConcept C185592680 @default.
- W2616134920 hasConcept C192562407 @default.
- W2616134920 hasConcept C202751555 @default.
- W2616134920 hasConcept C203014093 @default.
- W2616134920 hasConcept C207001950 @default.
- W2616134920 hasConcept C2780007613 @default.
- W2616134920 hasConcept C2780431358 @default.
- W2616134920 hasConcept C28328180 @default.
- W2616134920 hasConcept C2908915366 @default.