Matches in SemOpenAlex for { <https://semopenalex.org/work/W2616141856> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2616141856 endingPage "622" @default.
- W2616141856 startingPage "615" @default.
- W2616141856 abstract "Zhenjiang fragrant vinegar (Kozu) is a black rice vinegar that has been used as a traditional Chinese medicine and has various health benefits, including anti-obesity effects. In the present study, using luciferase reporter assays of PPARγ promoter activity, a novel ingredient from 8-year-old Kozu, 5-hydroxy-4-phenyl-butenolide, was isolated. The newly found agonist was named as “Fraglide-1”. Moreover, in subsequent experiments, it was confirmed that fraglide-1 was an PPARγ agonist and it could increase expression level of the uncoupling protein (UCP)-1. Fraglide-1 was chemically synthesized and it was verified that expression of the PPARγ was increased in dose dependent manner. Although Kozu has been consumed globally as a functional food for thousands of years, the mechanisms behind its health effects have not been characterized. The active ingredient of Kozu was successfully found and the results unraveled a longtime mystery about Kozu for its beneficial health effect." @default.
- W2616141856 created "2017-05-26" @default.
- W2616141856 creator A5046755067 @default.
- W2616141856 date "2017-01-01" @default.
- W2616141856 modified "2023-09-27" @default.
- W2616141856 title "A New Agonist for Peroxisome Proliferation-activated Receptor γ (PPARγ), Fraglide-1 from Zhenjiang Fragrant Vinegar: Screening and Characterization Based on Cell Culture Experiments" @default.
- W2616141856 cites W1896335412 @default.
- W2616141856 cites W1970187819 @default.
- W2616141856 cites W1987008486 @default.
- W2616141856 cites W1997389326 @default.
- W2616141856 cites W2040543985 @default.
- W2616141856 cites W2046253313 @default.
- W2616141856 cites W2048807613 @default.
- W2616141856 cites W2059501276 @default.
- W2616141856 cites W2104645520 @default.
- W2616141856 cites W2107207934 @default.
- W2616141856 cites W2115250702 @default.
- W2616141856 cites W2118055379 @default.
- W2616141856 cites W2142655199 @default.
- W2616141856 cites W2159301117 @default.
- W2616141856 cites W2318646204 @default.
- W2616141856 cites W2410023841 @default.
- W2616141856 cites W2495198598 @default.
- W2616141856 cites W4238497443 @default.
- W2616141856 cites W5241709 @default.
- W2616141856 cites W79782691 @default.
- W2616141856 doi "https://doi.org/10.5650/jos.ess16253" @default.
- W2616141856 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28515383" @default.
- W2616141856 hasPublicationYear "2017" @default.
- W2616141856 type Work @default.
- W2616141856 sameAs 2616141856 @default.
- W2616141856 citedByCount "5" @default.
- W2616141856 countsByYear W26161418562017 @default.
- W2616141856 countsByYear W26161418562018 @default.
- W2616141856 countsByYear W26161418562019 @default.
- W2616141856 countsByYear W26161418562020 @default.
- W2616141856 countsByYear W26161418562023 @default.
- W2616141856 crossrefType "journal-article" @default.
- W2616141856 hasAuthorship W2616141856A5046755067 @default.
- W2616141856 hasBestOaLocation W26161418561 @default.
- W2616141856 hasConcept C127078168 @default.
- W2616141856 hasConcept C170493617 @default.
- W2616141856 hasConcept C185592680 @default.
- W2616141856 hasConcept C187345961 @default.
- W2616141856 hasConcept C2778938600 @default.
- W2616141856 hasConcept C2780132029 @default.
- W2616141856 hasConcept C2780589914 @default.
- W2616141856 hasConcept C31903555 @default.
- W2616141856 hasConcept C55493867 @default.
- W2616141856 hasConcept C556039675 @default.
- W2616141856 hasConcept C58732023 @default.
- W2616141856 hasConcept C71924100 @default.
- W2616141856 hasConcept C86803240 @default.
- W2616141856 hasConcept C98274493 @default.
- W2616141856 hasConceptScore W2616141856C127078168 @default.
- W2616141856 hasConceptScore W2616141856C170493617 @default.
- W2616141856 hasConceptScore W2616141856C185592680 @default.
- W2616141856 hasConceptScore W2616141856C187345961 @default.
- W2616141856 hasConceptScore W2616141856C2778938600 @default.
- W2616141856 hasConceptScore W2616141856C2780132029 @default.
- W2616141856 hasConceptScore W2616141856C2780589914 @default.
- W2616141856 hasConceptScore W2616141856C31903555 @default.
- W2616141856 hasConceptScore W2616141856C55493867 @default.
- W2616141856 hasConceptScore W2616141856C556039675 @default.
- W2616141856 hasConceptScore W2616141856C58732023 @default.
- W2616141856 hasConceptScore W2616141856C71924100 @default.
- W2616141856 hasConceptScore W2616141856C86803240 @default.
- W2616141856 hasConceptScore W2616141856C98274493 @default.
- W2616141856 hasIssue "6" @default.
- W2616141856 hasLocation W26161418561 @default.
- W2616141856 hasLocation W26161418562 @default.
- W2616141856 hasOpenAccess W2616141856 @default.
- W2616141856 hasPrimaryLocation W26161418561 @default.
- W2616141856 hasRelatedWork W1963757324 @default.
- W2616141856 hasRelatedWork W2092961032 @default.
- W2616141856 hasRelatedWork W2559209921 @default.
- W2616141856 hasRelatedWork W2616141856 @default.
- W2616141856 hasRelatedWork W2953207889 @default.
- W2616141856 hasRelatedWork W2982437062 @default.
- W2616141856 hasRelatedWork W3152887989 @default.
- W2616141856 hasRelatedWork W3196242128 @default.
- W2616141856 hasRelatedWork W3202379820 @default.
- W2616141856 hasRelatedWork W3213863989 @default.
- W2616141856 hasVolume "66" @default.
- W2616141856 isParatext "false" @default.
- W2616141856 isRetracted "false" @default.
- W2616141856 magId "2616141856" @default.
- W2616141856 workType "article" @default.