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- W2616193713 abstract "Abstract SUPERmerge is a ChIP-seq read pileup analysis and annotation algorithm for investigating alignment (BAM) files of diffuse histone modification ChIP-seq datasets with broad chromatin domains at a single base pair resolution level. SUPERmerge allows flexible regulation of a variety of read pileup parameters, thereby revealing how read islands aggregate into areas of coverage across the genome and what annotation features they map to within individual biological replicates. SUPERmerge is especially useful for investigating low sample size ChIP-seq experiments in which epigenetic histone modifications (e.g., H3K9me1, H3K27me3) result in inherently broad peaks with a diffuse range of signal enrichment spanning multiple consecutive genomic loci and annotated features." @default.
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- W2616193713 date "2017-03-29" @default.
- W2616193713 modified "2023-09-23" @default.
- W2616193713 title "SUPERmerge: ChIP-seq coverage island analysis algorithm for broad histone marks" @default.
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- W2616193713 doi "https://doi.org/10.1101/121897" @default.
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