Matches in SemOpenAlex for { <https://semopenalex.org/work/W2616217781> ?p ?o ?g. }
- W2616217781 endingPage "7524" @default.
- W2616217781 startingPage "7520" @default.
- W2616217781 abstract "G-quadruplexes (G4s) are peculiar DNA or RNA tertiary structures that are involved in the regulation of many biological events within mammalian cells, bacteria, and viruses. Although their role as versatile therapeutic targets has been emphasized for 35 years, G4 selectivity over ubiquitous double-stranded DNA/RNA, as well as G4 differentiation by small molecules, still remains challenging. Here, a new amphiphilic dicyanovinyl-substituted squaraine, SQgl, is reported to act as an NIR fluorescent light-up probe discriminating an extensive panel of parallel G4s while it is non-fluorescent in the aggregated state. The squaraine can form an unconventional sandwich π-complex binding two quadruplexes, which leads to a strongly fluorescent (ΦF =0.61) supramolecular architecture. SQgl is highly selective against non-quadruplex and non-parallel G4 sequences without altering their topology, as desired for applications in selective in vivo high-resolution imaging and theranostics." @default.
- W2616217781 created "2017-05-26" @default.
- W2616217781 creator A5020717296 @default.
- W2616217781 creator A5068029711 @default.
- W2616217781 creator A5080213784 @default.
- W2616217781 creator A5083837684 @default.
- W2616217781 date "2017-05-19" @default.
- W2616217781 modified "2023-10-12" @default.
- W2616217781 title "An Aggregating Amphiphilic Squaraine: A Light-up Probe That Discriminates Parallel G-Quadruplexes" @default.
- W2616217781 cites W1450574606 @default.
- W2616217781 cites W1911558461 @default.
- W2616217781 cites W1954847968 @default.
- W2616217781 cites W1969396008 @default.
- W2616217781 cites W1979048721 @default.
- W2616217781 cites W1979628915 @default.
- W2616217781 cites W1985970608 @default.
- W2616217781 cites W1989129582 @default.
- W2616217781 cites W1992613137 @default.
- W2616217781 cites W2002563141 @default.
- W2616217781 cites W2007701572 @default.
- W2616217781 cites W2012006084 @default.
- W2616217781 cites W2015530480 @default.
- W2616217781 cites W2016359197 @default.
- W2616217781 cites W2017285656 @default.
- W2616217781 cites W2052392671 @default.
- W2616217781 cites W2055216168 @default.
- W2616217781 cites W2056072994 @default.
- W2616217781 cites W2059306569 @default.
- W2616217781 cites W2059539741 @default.
- W2616217781 cites W2060518352 @default.
- W2616217781 cites W2064935766 @default.
- W2616217781 cites W2074323251 @default.
- W2616217781 cites W2075316517 @default.
- W2616217781 cites W2081447956 @default.
- W2616217781 cites W2083085713 @default.
- W2616217781 cites W2111271543 @default.
- W2616217781 cites W2115766017 @default.
- W2616217781 cites W2117768735 @default.
- W2616217781 cites W2119684905 @default.
- W2616217781 cites W2120320398 @default.
- W2616217781 cites W2124778400 @default.
- W2616217781 cites W2127213026 @default.
- W2616217781 cites W2137500638 @default.
- W2616217781 cites W2143964514 @default.
- W2616217781 cites W2145745052 @default.
- W2616217781 cites W2146381798 @default.
- W2616217781 cites W2155773930 @default.
- W2616217781 cites W2156049851 @default.
- W2616217781 cites W2159128272 @default.
- W2616217781 cites W2165501619 @default.
- W2616217781 cites W2196560216 @default.
- W2616217781 cites W2213504946 @default.
- W2616217781 cites W2259183429 @default.
- W2616217781 cites W2260226283 @default.
- W2616217781 cites W2268343952 @default.
- W2616217781 cites W2268480512 @default.
- W2616217781 cites W2273058296 @default.
- W2616217781 cites W2282017918 @default.
- W2616217781 cites W2314764775 @default.
- W2616217781 cites W2319721215 @default.
- W2616217781 cites W2331003220 @default.
- W2616217781 cites W2425681130 @default.
- W2616217781 cites W2426177481 @default.
- W2616217781 cites W2583080711 @default.
- W2616217781 cites W4206881430 @default.
- W2616217781 cites W4236379899 @default.
- W2616217781 cites W4252958962 @default.
- W2616217781 cites W2115218099 @default.
- W2616217781 doi "https://doi.org/10.1002/anie.201702096" @default.
- W2616217781 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28524354" @default.
- W2616217781 hasPublicationYear "2017" @default.
- W2616217781 type Work @default.
- W2616217781 sameAs 2616217781 @default.
- W2616217781 citedByCount "74" @default.
- W2616217781 countsByYear W26162177812017 @default.
- W2616217781 countsByYear W26162177812018 @default.
- W2616217781 countsByYear W26162177812019 @default.
- W2616217781 countsByYear W26162177812020 @default.
- W2616217781 countsByYear W26162177812021 @default.
- W2616217781 countsByYear W26162177812022 @default.
- W2616217781 countsByYear W26162177812023 @default.
- W2616217781 crossrefType "journal-article" @default.
- W2616217781 hasAuthorship W2616217781A5020717296 @default.
- W2616217781 hasAuthorship W2616217781A5068029711 @default.
- W2616217781 hasAuthorship W2616217781A5080213784 @default.
- W2616217781 hasAuthorship W2616217781A5083837684 @default.
- W2616217781 hasConcept C104317684 @default.
- W2616217781 hasConcept C121332964 @default.
- W2616217781 hasConcept C12554922 @default.
- W2616217781 hasConcept C15920480 @default.
- W2616217781 hasConcept C171250308 @default.
- W2616217781 hasConcept C178790620 @default.
- W2616217781 hasConcept C185592680 @default.
- W2616217781 hasConcept C192562407 @default.
- W2616217781 hasConcept C21951064 @default.
- W2616217781 hasConcept C32909587 @default.
- W2616217781 hasConcept C521977710 @default.
- W2616217781 hasConcept C552990157 @default.