Matches in SemOpenAlex for { <https://semopenalex.org/work/W2616385265> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2616385265 endingPage "1005" @default.
- W2616385265 startingPage "999" @default.
- W2616385265 abstract "Renin angiotensin antagonists (RAA) may block protective vasopressor responses during surgery. Evidence linking RAA with intraoperative hypotension and perioperative adverse events is conflicting.To compare the incidence of intraoperative hypotension and adverse events between patients receiving or not receiving RAA.This is a retrospective case-control study of 258 consecutive patients who underwent elective total knee or hip replacement between 1 January 2013 and 31 August 2016 and who were chronically prescribed a single blood pressure-lowering agent up to the time of surgery. Primary outcome measures were differences between patients receiving RAA (cases; n = 129) and patients receiving non-RAA medications (controls; n = 129) in incidence of intraoperative hypotension (systolic blood pressure <90 mmHg), perioperative acute kidney injury (AKI, >30% increase in serum creatinine from baseline on Day 1 post-operatively) and new onset major adverse cardiac or cerebrovascular events (MACCE) or in-hospital death over 72 h post-operatively.Patients receiving RAA had significantly higher preoperative systolic blood pressure, greater prevalence of hypertension and chronic kidney disease, lower prevalence of ischaemic heart disease and lower cardiac risk compared to controls. Age, gender, type of operation, operative fitness, mode and duration of anaesthesia and prevalence of other types of cardiovascular disease, dyslipidaemia and diabetes were similar between groups. Compared to controls, patients receiving RAA had higher incidence of intraoperative hypotension (76.0 vs 45.9%, P < 0.001), AKI (11.6 vs 1.6%, P = 0.002) and MACCE (6.2 vs 0%, P = 0.007), with all adverse events associated with intraoperative hypotension.This study provides further observational evidence of RAA-induced harm in patients undergoing elective surgery, although determining benefits and harms of preoperative withdrawal of RRA requires prospective randomised trials." @default.
- W2616385265 created "2017-05-26" @default.
- W2616385265 creator A5010242520 @default.
- W2616385265 creator A5057603989 @default.
- W2616385265 creator A5089518233 @default.
- W2616385265 date "2017-09-01" @default.
- W2616385265 modified "2023-09-26" @default.
- W2616385265 title "Association of renin angiotensin antagonists with adverse perioperative events in patients undergoing elective orthopaedic surgery: a case-control study" @default.
- W2616385265 cites W140188979 @default.
- W2616385265 cites W1591811224 @default.
- W2616385265 cites W1806462585 @default.
- W2616385265 cites W1896781386 @default.
- W2616385265 cites W1939265809 @default.
- W2616385265 cites W1963710671 @default.
- W2616385265 cites W2004302295 @default.
- W2616385265 cites W2025637304 @default.
- W2616385265 cites W2030121577 @default.
- W2616385265 cites W2083391328 @default.
- W2616385265 cites W2096960069 @default.
- W2616385265 cites W2106171307 @default.
- W2616385265 cites W2125918815 @default.
- W2616385265 cites W2130923119 @default.
- W2616385265 cites W2166110846 @default.
- W2616385265 cites W2285459543 @default.
- W2616385265 cites W2331586814 @default.
- W2616385265 cites W2334586393 @default.
- W2616385265 cites W2416853656 @default.
- W2616385265 cites W2528946345 @default.
- W2616385265 cites W2537440053 @default.
- W2616385265 cites W2541386048 @default.
- W2616385265 cites W2616838800 @default.
- W2616385265 doi "https://doi.org/10.1111/imj.13487" @default.
- W2616385265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28509399" @default.
- W2616385265 hasPublicationYear "2017" @default.
- W2616385265 type Work @default.
- W2616385265 sameAs 2616385265 @default.
- W2616385265 citedByCount "6" @default.
- W2616385265 countsByYear W26163852652018 @default.
- W2616385265 countsByYear W26163852652019 @default.
- W2616385265 countsByYear W26163852652020 @default.
- W2616385265 countsByYear W26163852652022 @default.
- W2616385265 crossrefType "journal-article" @default.
- W2616385265 hasAuthorship W2616385265A5010242520 @default.
- W2616385265 hasAuthorship W2616385265A5057603989 @default.
- W2616385265 hasAuthorship W2616385265A5089518233 @default.
- W2616385265 hasConcept C120665830 @default.
- W2616385265 hasConcept C121332964 @default.
- W2616385265 hasConcept C126322002 @default.
- W2616385265 hasConcept C141071460 @default.
- W2616385265 hasConcept C167135981 @default.
- W2616385265 hasConcept C197934379 @default.
- W2616385265 hasConcept C2778653478 @default.
- W2616385265 hasConcept C2780472472 @default.
- W2616385265 hasConcept C31174226 @default.
- W2616385265 hasConcept C42219234 @default.
- W2616385265 hasConcept C61511704 @default.
- W2616385265 hasConcept C71924100 @default.
- W2616385265 hasConcept C84393581 @default.
- W2616385265 hasConceptScore W2616385265C120665830 @default.
- W2616385265 hasConceptScore W2616385265C121332964 @default.
- W2616385265 hasConceptScore W2616385265C126322002 @default.
- W2616385265 hasConceptScore W2616385265C141071460 @default.
- W2616385265 hasConceptScore W2616385265C167135981 @default.
- W2616385265 hasConceptScore W2616385265C197934379 @default.
- W2616385265 hasConceptScore W2616385265C2778653478 @default.
- W2616385265 hasConceptScore W2616385265C2780472472 @default.
- W2616385265 hasConceptScore W2616385265C31174226 @default.
- W2616385265 hasConceptScore W2616385265C42219234 @default.
- W2616385265 hasConceptScore W2616385265C61511704 @default.
- W2616385265 hasConceptScore W2616385265C71924100 @default.
- W2616385265 hasConceptScore W2616385265C84393581 @default.
- W2616385265 hasIssue "9" @default.
- W2616385265 hasLocation W26163852651 @default.
- W2616385265 hasLocation W26163852652 @default.
- W2616385265 hasOpenAccess W2616385265 @default.
- W2616385265 hasPrimaryLocation W26163852651 @default.
- W2616385265 hasRelatedWork W2047967234 @default.
- W2616385265 hasRelatedWork W2352247659 @default.
- W2616385265 hasRelatedWork W2354785620 @default.
- W2616385265 hasRelatedWork W2375359181 @default.
- W2616385265 hasRelatedWork W2586998360 @default.
- W2616385265 hasRelatedWork W2767618185 @default.
- W2616385265 hasRelatedWork W3172519280 @default.
- W2616385265 hasRelatedWork W4213205744 @default.
- W2616385265 hasRelatedWork W4324096639 @default.
- W2616385265 hasRelatedWork W3006168697 @default.
- W2616385265 hasVolume "47" @default.
- W2616385265 isParatext "false" @default.
- W2616385265 isRetracted "false" @default.
- W2616385265 magId "2616385265" @default.
- W2616385265 workType "article" @default.