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• W2616405812 abstract "Background Although the patient perspective is implicit in the practice of medicine, research evaluating this remains scarce. In a climate where clinicians and policy‐makers constantly strive to achieve more patient‐centred models of care, this omission warrants attention. Aim To assess health‐related quality of life (Hr QoL ) in women under 25 years of age with cervical intra‐epithelial neoplasia grade 2 ( CIN 2) receiving conservative management (colposcopy follow‐up, with treatment if necessary) compared with those receiving immediate excisional treatment with large loop excision of the transformation zone ( LLETZ ). Methods An observational study evaluating Hr QoL was conducted at Christchurch Women's Hospital, New Zealand. Women undergoing conservative management for CIN 2 were compared with those undergoing immediate excisional treatment in an age‐matched sample. The Short Form Health Survey 12 version 2 ( SF ‐12v2) was used to evaluate Hr QoL . Secondary outcomes of anxiety and sexual function were also assessed. Results One hundred and four women with CIN 2 participated in the study. Of these, 63 (60%) received conservative management and 41 (40%) received immediate excisional treatment with LLETZ . We found no significant difference in Hr QoL between the groups in a multivariate regression analysis adjusted for parity, smoking and socioeconomic status. There were also no significant differences in sexual function or anxiety. Conclusion We found no difference in Hr QoL by management strategy. Conservative management of CIN 2 in women under 25 is unlikely to have an adverse impact on self‐reported HrQoL, anxiety or sexual functioning compared with conventional management." @default.
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• W2616405812 date "2017-05-16" @default.
• W2616405812 modified "2023-09-23" @default.
• W2616405812 title "Initial observation of CIN2 does not appear to reduce quality of life in women under 25 years of age" @default.
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• W2616405812 doi "https://doi.org/10.1111/ajo.12633" @default.
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