Matches in SemOpenAlex for { <https://semopenalex.org/work/W2616579991> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2616579991 abstract "Introduction. The liver is one of the most important organs of the human body, performing a number of important functions. Among the common liver diseases, infiltrative pathologies we distinguished: fatty degeneration, lymphomas, amyloidosis, sarcoidosis and tuberculosis. Characterizing liver disease, the manifestations of disorders are divided into syndromes that help to diagnose a particular disease of the liver and determine its causes. In particular – the cytolytic syndrome (CS).The aim of the study – to examine the CS markers in the case of liver dysfunction in patients with newly diagnosed lung tuberculosis prior to treatment and after two months of therapy with first-line anti-tuberculosis drugs.Methods of the research. Two groups of people were examined: the 1st control group of practically healthy donors – 34 people; and the 2nd – patients with newly diagnosed pulmonary tuberculosis prior to treatment and after two months of therapy with first-line anti-tuberculosis drugs (31 people). All patients underwent standard biochemical blood tests, ultrasound of the liver in dynamics. The spectrum of biochemical blood test parameters included determination of alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH) and γ-glutamyltranspeptidase (GGTP).Results and Discussion. The obtained data testifying to occurrence of CS in newly diagnosed tuberculosis patients before the start of treatment are confirmed by the tendency to increase the levels of AST and GGTP. Especially such changes are observed after intensive therapy with antituberculous drugs. There are likely changes in such markers as ALT, LDH and GGTP.Conclusions. It is established that tuberculous intoxication can affect the functional state of the liver. After prolonged treatment of patients with pulmonary tuberculosis, an increase in the indices of such markers of cytolysis as ALT, LDH and GGTP is observed. Disturbance of liver function during therapy may be due to the hepatotoxic effect of anti-tuberculosis drugs, which necessitates the appointment for patients hepatoprotectors." @default.
- W2616579991 created "2017-05-26" @default.
- W2616579991 creator A5006651775 @default.
- W2616579991 creator A5027175117 @default.
- W2616579991 creator A5046150224 @default.
- W2616579991 creator A5064368821 @default.
- W2616579991 creator A5073167482 @default.
- W2616579991 date "2017-04-28" @default.
- W2616579991 modified "2023-09-28" @default.
- W2616579991 title "Діагностика цитолітичного синдрому у хворих на туберкульоз легень" @default.
- W2616579991 cites W2044422047 @default.
- W2616579991 cites W2400943042 @default.
- W2616579991 doi "https://doi.org/10.11603/mcch.2410-681x.2017.v0.i1.7684" @default.
- W2616579991 hasPublicationYear "2017" @default.
- W2616579991 type Work @default.
- W2616579991 sameAs 2616579991 @default.
- W2616579991 citedByCount "0" @default.
- W2616579991 crossrefType "journal-article" @default.
- W2616579991 hasAuthorship W2616579991A5006651775 @default.
- W2616579991 hasAuthorship W2616579991A5027175117 @default.
- W2616579991 hasAuthorship W2616579991A5046150224 @default.
- W2616579991 hasAuthorship W2616579991A5064368821 @default.
- W2616579991 hasAuthorship W2616579991A5073167482 @default.
- W2616579991 hasBestOaLocation W26165799911 @default.
- W2616579991 hasConcept C126322002 @default.
- W2616579991 hasConcept C142724271 @default.
- W2616579991 hasConcept C181199279 @default.
- W2616579991 hasConcept C185592680 @default.
- W2616579991 hasConcept C2777318727 @default.
- W2616579991 hasConcept C2779134260 @default.
- W2616579991 hasConcept C2781069245 @default.
- W2616579991 hasConcept C512861765 @default.
- W2616579991 hasConcept C55493867 @default.
- W2616579991 hasConcept C71924100 @default.
- W2616579991 hasConcept C90924648 @default.
- W2616579991 hasConceptScore W2616579991C126322002 @default.
- W2616579991 hasConceptScore W2616579991C142724271 @default.
- W2616579991 hasConceptScore W2616579991C181199279 @default.
- W2616579991 hasConceptScore W2616579991C185592680 @default.
- W2616579991 hasConceptScore W2616579991C2777318727 @default.
- W2616579991 hasConceptScore W2616579991C2779134260 @default.
- W2616579991 hasConceptScore W2616579991C2781069245 @default.
- W2616579991 hasConceptScore W2616579991C512861765 @default.
- W2616579991 hasConceptScore W2616579991C55493867 @default.
- W2616579991 hasConceptScore W2616579991C71924100 @default.
- W2616579991 hasConceptScore W2616579991C90924648 @default.
- W2616579991 hasLocation W26165799911 @default.
- W2616579991 hasOpenAccess W2616579991 @default.
- W2616579991 hasPrimaryLocation W26165799911 @default.
- W2616579991 hasRelatedWork W1500505296 @default.
- W2616579991 hasRelatedWork W2012942993 @default.
- W2616579991 hasRelatedWork W2112252793 @default.
- W2616579991 hasRelatedWork W2146425468 @default.
- W2616579991 hasRelatedWork W2292211016 @default.
- W2616579991 hasRelatedWork W2351688798 @default.
- W2616579991 hasRelatedWork W2353236418 @default.
- W2616579991 hasRelatedWork W2356399959 @default.
- W2616579991 hasRelatedWork W2369470082 @default.
- W2616579991 hasRelatedWork W2371870982 @default.
- W2616579991 hasRelatedWork W2372949875 @default.
- W2616579991 hasRelatedWork W2383325781 @default.
- W2616579991 hasRelatedWork W2384923925 @default.
- W2616579991 hasRelatedWork W2389876484 @default.
- W2616579991 hasRelatedWork W2390606551 @default.
- W2616579991 hasRelatedWork W2403542448 @default.
- W2616579991 hasRelatedWork W2465375134 @default.
- W2616579991 hasRelatedWork W2471896267 @default.
- W2616579991 hasRelatedWork W2903700968 @default.
- W2616579991 hasRelatedWork W3026355875 @default.
- W2616579991 isParatext "false" @default.
- W2616579991 isRetracted "false" @default.
- W2616579991 magId "2616579991" @default.
- W2616579991 workType "article" @default.