Matches in SemOpenAlex for { <https://semopenalex.org/work/W2616939534> ?p ?o ?g. }
- W2616939534 endingPage "196" @default.
- W2616939534 startingPage "189" @default.
- W2616939534 abstract "Multiple myeloma (MM) is one of the hematological malignancies that require palliative care. This is because of the life-threatening nature and the suffering associated with the illness. The aim of this study is to bring to the fore the complications experienced by people living with MM in the Niger-Delta region of Nigeria and the outcome of various palliative interventions.This was a 10-year multi-center retrospective study of 26 patients diagnosed and managed in three major centers in the Niger-Delta region of Nigeria from January 2003 to December 2012. Information on the clinical, laboratory, radiological data, and palliative treatment was obtained at presentation and subsequently at intervals of 3 months until the patient was lost to follow-up.The mean duration from onset of symptoms to diagnosis was 13.12 months (95% CI, 6.65-19.58). A total of 16 (61.5%), eight (30.8%), and two subjects (7.7%) presented in Durie-Salmon (DS) stages III, II, and I, respectively. The complications presented by patients at diagnoses included bone pain (84.6%), anemia (61.5%), nephropathy (23.1%), and hemiplegia (35%). All the patients received analgesics, while 50.0% received blood transfusion, 56.7% had surgery performed, 19% had hemodialysis, and 3.8% received radiotherapy. A total of 10 (38%) patients benefited from bisphosphonates (BPs). A total of 57.6% of patients were on melphalan-prednisone (MP) double regimen, while 19% and 8% patients were on MP-thalidomide and MP-bortezomib triple regimens, respectively. A total of 3.8% of patients at DS stage IIIB disease had autologous stem-cell transplantation (ASCT). Only 7.6% of the myeloma patients survived up to 5 years post diagnosis. The overall mean survival interval was 39.7 months (95% CI, 32.1-47.2).Late diagnosis and inadequate palliative care account for major complications encountered by MM patients in the Niger-Delta region of Nigeria. This could be responsible for the poor prognostic outcome and low survival interval of MM individuals in this region. There is, therefore, a need to improve the quality of palliative care received by myeloma patients in this region. This is achievable via provision of relevant and affordable health care facilities for diagnosis and treatment of the disease." @default.
- W2616939534 created "2017-06-05" @default.
- W2616939534 creator A5003719328 @default.
- W2616939534 creator A5032007944 @default.
- W2616939534 creator A5069303834 @default.
- W2616939534 creator A5080866996 @default.
- W2616939534 date "2017-05-01" @default.
- W2616939534 modified "2023-10-17" @default.
- W2616939534 title "Multiple myeloma in Niger Delta, Nigeria: complications and the outcome of palliative interventions" @default.
- W2616939534 cites W1593617246 @default.
- W2616939534 cites W1801543025 @default.
- W2616939534 cites W1903277992 @default.
- W2616939534 cites W1995093156 @default.
- W2616939534 cites W1998700496 @default.
- W2616939534 cites W1999549312 @default.
- W2616939534 cites W2002929279 @default.
- W2616939534 cites W2006382315 @default.
- W2616939534 cites W2020830322 @default.
- W2616939534 cites W2031157863 @default.
- W2616939534 cites W2047794102 @default.
- W2616939534 cites W2066800926 @default.
- W2616939534 cites W2076668534 @default.
- W2616939534 cites W2091372100 @default.
- W2616939534 cites W2100738529 @default.
- W2616939534 cites W2110466835 @default.
- W2616939534 cites W2118102423 @default.
- W2616939534 cites W2120474651 @default.
- W2616939534 cites W2130897575 @default.
- W2616939534 cites W2135455274 @default.
- W2616939534 cites W2147769421 @default.
- W2616939534 cites W2164807675 @default.
- W2616939534 cites W2170515647 @default.
- W2616939534 cites W2341526758 @default.
- W2616939534 cites W4211082074 @default.
- W2616939534 cites W1963963698 @default.
- W2616939534 doi "https://doi.org/10.2147/cmar.s126136" @default.
- W2616939534 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5446965" @default.
- W2616939534 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28579833" @default.
- W2616939534 hasPublicationYear "2017" @default.
- W2616939534 type Work @default.
- W2616939534 sameAs 2616939534 @default.
- W2616939534 citedByCount "11" @default.
- W2616939534 countsByYear W26169395342018 @default.
- W2616939534 countsByYear W26169395342019 @default.
- W2616939534 countsByYear W26169395342020 @default.
- W2616939534 countsByYear W26169395342021 @default.
- W2616939534 countsByYear W26169395342022 @default.
- W2616939534 crossrefType "journal-article" @default.
- W2616939534 hasAuthorship W2616939534A5003719328 @default.
- W2616939534 hasAuthorship W2616939534A5032007944 @default.
- W2616939534 hasAuthorship W2616939534A5069303834 @default.
- W2616939534 hasAuthorship W2616939534A5080866996 @default.
- W2616939534 hasBestOaLocation W26169395341 @default.
- W2616939534 hasConcept C118552586 @default.
- W2616939534 hasConcept C126322002 @default.
- W2616939534 hasConcept C141071460 @default.
- W2616939534 hasConcept C159110408 @default.
- W2616939534 hasConcept C167135981 @default.
- W2616939534 hasConcept C187212893 @default.
- W2616939534 hasConcept C27415008 @default.
- W2616939534 hasConcept C2776364478 @default.
- W2616939534 hasConcept C2778248108 @default.
- W2616939534 hasConcept C2778684742 @default.
- W2616939534 hasConcept C2779609412 @default.
- W2616939534 hasConcept C2780014101 @default.
- W2616939534 hasConcept C2781413609 @default.
- W2616939534 hasConcept C2994186709 @default.
- W2616939534 hasConcept C71924100 @default.
- W2616939534 hasConceptScore W2616939534C118552586 @default.
- W2616939534 hasConceptScore W2616939534C126322002 @default.
- W2616939534 hasConceptScore W2616939534C141071460 @default.
- W2616939534 hasConceptScore W2616939534C159110408 @default.
- W2616939534 hasConceptScore W2616939534C167135981 @default.
- W2616939534 hasConceptScore W2616939534C187212893 @default.
- W2616939534 hasConceptScore W2616939534C27415008 @default.
- W2616939534 hasConceptScore W2616939534C2776364478 @default.
- W2616939534 hasConceptScore W2616939534C2778248108 @default.
- W2616939534 hasConceptScore W2616939534C2778684742 @default.
- W2616939534 hasConceptScore W2616939534C2779609412 @default.
- W2616939534 hasConceptScore W2616939534C2780014101 @default.
- W2616939534 hasConceptScore W2616939534C2781413609 @default.
- W2616939534 hasConceptScore W2616939534C2994186709 @default.
- W2616939534 hasConceptScore W2616939534C71924100 @default.
- W2616939534 hasLocation W26169395341 @default.
- W2616939534 hasLocation W26169395342 @default.
- W2616939534 hasLocation W26169395343 @default.
- W2616939534 hasLocation W26169395344 @default.
- W2616939534 hasOpenAccess W2616939534 @default.
- W2616939534 hasPrimaryLocation W26169395341 @default.
- W2616939534 hasRelatedWork W2023702847 @default.
- W2616939534 hasRelatedWork W2045490472 @default.
- W2616939534 hasRelatedWork W2088313945 @default.
- W2616939534 hasRelatedWork W2112489854 @default.
- W2616939534 hasRelatedWork W2364383807 @default.
- W2616939534 hasRelatedWork W2559593973 @default.
- W2616939534 hasRelatedWork W2957896353 @default.
- W2616939534 hasRelatedWork W3032328885 @default.
- W2616939534 hasRelatedWork W3032436580 @default.