Matches in SemOpenAlex for { <https://semopenalex.org/work/W2617114007> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2617114007 endingPage "246" @default.
- W2617114007 startingPage "234" @default.
- W2617114007 abstract "Objective: The present study investigates the effect of Withania somnifera (WS), a well known adaptogenic agent in Indian system of Medicine, on acute cerebral reperfusion and long-term cerebral hypoperfusion in rats. Materials and methods: Acute ischemia-reperfusion (30 min occlusion of bilateral common carotid arteries followed by 45 min reperfusion) and Long-term cerebral hypoperfusion (for 15 days) in C.F. strain rats were produced following standard technique. WS, Indian chemotype-1, rich in withanolide glycosides (= sitoindosides) was used for the present study. Effect of WS on lipid peroxidation, superoxide dismutase (SOD) activity, cyclic AMP level and histopathological changes in forebrain regions in acute ischemia - reperfusion and on long-term cerebral hypoperfusion induced behavioral and histopathological alterations were evaluated. Results: WS pre-treatment (50 mg/kg p.o. for 5 days) attenuated the reperfusion induced biochemical and histopathological alterations. Long term hypoperfusion induced anxiety and listlessness (open field paradigm) accompanied by deficits in learning and memory (Morris' water maze testing) along with histopathological changes in rat forebrains were attenuated with WS treatment. Conclusion: The results suggest that WS may be useful in cerebrovascular insufficiency conditions." @default.
- W2617114007 created "2017-06-05" @default.
- W2617114007 creator A5001888687 @default.
- W2617114007 creator A5013564419 @default.
- W2617114007 creator A5051761393 @default.
- W2617114007 creator A5080150525 @default.
- W2617114007 creator A5082890572 @default.
- W2617114007 date "2007-06-01" @default.
- W2617114007 modified "2023-09-22" @default.
- W2617114007 title "Neuroprotective Effect of Withania somnifera (WS) in Cerebral Ischemia-Reperfusion and Long-Term Hypoperfusion Induced Alterations in Rats" @default.
- W2617114007 doi "https://doi.org/10.18311/jnr/2007/315" @default.
- W2617114007 hasPublicationYear "2007" @default.
- W2617114007 type Work @default.
- W2617114007 sameAs 2617114007 @default.
- W2617114007 citedByCount "4" @default.
- W2617114007 countsByYear W26171140072014 @default.
- W2617114007 countsByYear W26171140072015 @default.
- W2617114007 crossrefType "journal-article" @default.
- W2617114007 hasAuthorship W2617114007A5001888687 @default.
- W2617114007 hasAuthorship W2617114007A5013564419 @default.
- W2617114007 hasAuthorship W2617114007A5051761393 @default.
- W2617114007 hasAuthorship W2617114007A5080150525 @default.
- W2617114007 hasAuthorship W2617114007A5082890572 @default.
- W2617114007 hasConcept C126322002 @default.
- W2617114007 hasConcept C142724271 @default.
- W2617114007 hasConcept C146957229 @default.
- W2617114007 hasConcept C204787440 @default.
- W2617114007 hasConcept C25498285 @default.
- W2617114007 hasConcept C2775838275 @default.
- W2617114007 hasConcept C2776151105 @default.
- W2617114007 hasConcept C2780069950 @default.
- W2617114007 hasConcept C2780829032 @default.
- W2617114007 hasConcept C2781161787 @default.
- W2617114007 hasConcept C42219234 @default.
- W2617114007 hasConcept C44752575 @default.
- W2617114007 hasConcept C541997718 @default.
- W2617114007 hasConcept C71924100 @default.
- W2617114007 hasConcept C98274493 @default.
- W2617114007 hasConceptScore W2617114007C126322002 @default.
- W2617114007 hasConceptScore W2617114007C142724271 @default.
- W2617114007 hasConceptScore W2617114007C146957229 @default.
- W2617114007 hasConceptScore W2617114007C204787440 @default.
- W2617114007 hasConceptScore W2617114007C25498285 @default.
- W2617114007 hasConceptScore W2617114007C2775838275 @default.
- W2617114007 hasConceptScore W2617114007C2776151105 @default.
- W2617114007 hasConceptScore W2617114007C2780069950 @default.
- W2617114007 hasConceptScore W2617114007C2780829032 @default.
- W2617114007 hasConceptScore W2617114007C2781161787 @default.
- W2617114007 hasConceptScore W2617114007C42219234 @default.
- W2617114007 hasConceptScore W2617114007C44752575 @default.
- W2617114007 hasConceptScore W2617114007C541997718 @default.
- W2617114007 hasConceptScore W2617114007C71924100 @default.
- W2617114007 hasConceptScore W2617114007C98274493 @default.
- W2617114007 hasIssue "2" @default.
- W2617114007 hasLocation W26171140071 @default.
- W2617114007 hasOpenAccess W2617114007 @default.
- W2617114007 hasPrimaryLocation W26171140071 @default.
- W2617114007 hasRelatedWork W1716137532 @default.
- W2617114007 hasRelatedWork W1968148753 @default.
- W2617114007 hasRelatedWork W1984428342 @default.
- W2617114007 hasRelatedWork W2014441885 @default.
- W2617114007 hasRelatedWork W2055362926 @default.
- W2617114007 hasRelatedWork W2065561101 @default.
- W2617114007 hasRelatedWork W2074676693 @default.
- W2617114007 hasRelatedWork W2164066101 @default.
- W2617114007 hasRelatedWork W2366662162 @default.
- W2617114007 hasRelatedWork W2372714419 @default.
- W2617114007 hasRelatedWork W2375323386 @default.
- W2617114007 hasRelatedWork W2403511295 @default.
- W2617114007 hasRelatedWork W2415483332 @default.
- W2617114007 hasRelatedWork W2560273853 @default.
- W2617114007 hasRelatedWork W2788375907 @default.
- W2617114007 hasRelatedWork W2891027425 @default.
- W2617114007 hasRelatedWork W2994873596 @default.
- W2617114007 hasRelatedWork W3150845133 @default.
- W2617114007 hasRelatedWork W3164128083 @default.
- W2617114007 hasRelatedWork W3177100262 @default.
- W2617114007 hasVolume "7" @default.
- W2617114007 isParatext "false" @default.
- W2617114007 isRetracted "false" @default.
- W2617114007 magId "2617114007" @default.
- W2617114007 workType "article" @default.