Matches in SemOpenAlex for { <https://semopenalex.org/work/W2617231816> ?p ?o ?g. }
- W2617231816 abstract "Anxiety disorders affect approximately 1 in 5 (18%) Americans within a given 1 year period, placing a substantial burden on the national health care system. Therefore, there is a critical need to understand the neural mechanisms mediating anxiety symptoms. We used unbiased, multimodal, data-driven, whole-brain measures of neural activity (magnetoencephalography) and connectivity (fMRI) to identify the regions of the brain that contribute most prominently to sustained anxiety. We report that a single brain region, the intraparietal sulcus (IPS), shows both elevated neural activity and global brain connectivity during threat. The IPS plays a key role in attention orienting and may contribute to the hypervigilance that is a common symptom of pathological anxiety. Hyperactivation of this region during elevated state anxiety may account for the paradoxical facilitation of performance on tasks that require an external focus of attention, and impairment of performance on tasks that require an internal focus of attention." @default.
- W2617231816 created "2017-06-05" @default.
- W2617231816 creator A5003787994 @default.
- W2617231816 creator A5009835857 @default.
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- W2617231816 creator A5059158790 @default.
- W2617231816 creator A5069510449 @default.
- W2617231816 creator A5074496772 @default.
- W2617231816 date "2017-05-30" @default.
- W2617231816 modified "2023-10-18" @default.
- W2617231816 title "Threat of shock increases excitability and connectivity of the intraparietal sulcus" @default.
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