Matches in SemOpenAlex for { <https://semopenalex.org/work/W2617372202> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2617372202 endingPage "22" @default.
- W2617372202 startingPage "13" @default.
- W2617372202 abstract "The purpose of this work was to use noninvasive in vivo MRI to characterize the substrate (i.e., known as gray zone, GZ) of ventricular arrhythmia, a major cause of sudden death. Our aim was to use a preclinical model of chronic infarction to study the structural and molecular characteristics of infarcted areas. For this, we related parametric T1 maps with the density of collagen and gap junctions (Cx43 proteins) in patchy fibrosis in n = 6 swine with chronic infarction. Specifically, in vivo T1 relaxation maps were calculated from 2D multi-contrast late enhancement (MCLE) MR images obtained at 1 × 1 × 5 mm resolution. Quantitative analysis and regression analysis demonstrated that the comparison between GZ and scar extent in MCLE to the corresponding areas identified in histology, yielded very good correlations in both cases (i.e., goodness of fit: R2 = 0.89 for GZ, and 0.92 for dense scar, respectively). Furthermore, the gap junction Cx43 density was significantly reduced (i.e., by > 50%) in the ischemic GZ areas determined from MCLE. These novel results suggest that in vivo 2D parametric T1 maps can be used to evaluate the biophysical properties of healing myocardium post-infarction, and to distinguish between the infarct categories (i.e., scar vs. GZ) with re-modelled structural and electrical characteristics." @default.
- W2617372202 created "2017-06-05" @default.
- W2617372202 creator A5009381551 @default.
- W2617372202 creator A5042885686 @default.
- W2617372202 creator A5066716873 @default.
- W2617372202 creator A5079763837 @default.
- W2617372202 creator A5081777957 @default.
- W2617372202 date "2017-01-01" @default.
- W2617372202 modified "2023-09-29" @default.
- W2617372202 title "In Vivo Parametric T1 Maps Correlate with Structural and Molecular Characteristics of Focal Fibrosis" @default.
- W2617372202 cites W1573024517 @default.
- W2617372202 cites W1994643849 @default.
- W2617372202 cites W1996751178 @default.
- W2617372202 cites W2047970481 @default.
- W2617372202 cites W2070722083 @default.
- W2617372202 cites W2078321501 @default.
- W2617372202 cites W2084221153 @default.
- W2617372202 cites W2100831002 @default.
- W2617372202 cites W2120787331 @default.
- W2617372202 cites W2139302418 @default.
- W2617372202 cites W2142902382 @default.
- W2617372202 cites W2144220673 @default.
- W2617372202 cites W2153144629 @default.
- W2617372202 cites W2161947705 @default.
- W2617372202 cites W2519911837 @default.
- W2617372202 doi "https://doi.org/10.1007/978-3-319-59448-4_2" @default.
- W2617372202 hasPublicationYear "2017" @default.
- W2617372202 type Work @default.
- W2617372202 sameAs 2617372202 @default.
- W2617372202 citedByCount "1" @default.
- W2617372202 countsByYear W26173722022018 @default.
- W2617372202 crossrefType "book-chapter" @default.
- W2617372202 hasAuthorship W2617372202A5009381551 @default.
- W2617372202 hasAuthorship W2617372202A5042885686 @default.
- W2617372202 hasAuthorship W2617372202A5066716873 @default.
- W2617372202 hasAuthorship W2617372202A5079763837 @default.
- W2617372202 hasAuthorship W2617372202A5081777957 @default.
- W2617372202 hasConcept C105795698 @default.
- W2617372202 hasConcept C117251300 @default.
- W2617372202 hasConcept C136229726 @default.
- W2617372202 hasConcept C142724271 @default.
- W2617372202 hasConcept C150903083 @default.
- W2617372202 hasConcept C164705383 @default.
- W2617372202 hasConcept C207001950 @default.
- W2617372202 hasConcept C2777798775 @default.
- W2617372202 hasConcept C2780559512 @default.
- W2617372202 hasConcept C33923547 @default.
- W2617372202 hasConcept C500558357 @default.
- W2617372202 hasConcept C71924100 @default.
- W2617372202 hasConcept C86803240 @default.
- W2617372202 hasConceptScore W2617372202C105795698 @default.
- W2617372202 hasConceptScore W2617372202C117251300 @default.
- W2617372202 hasConceptScore W2617372202C136229726 @default.
- W2617372202 hasConceptScore W2617372202C142724271 @default.
- W2617372202 hasConceptScore W2617372202C150903083 @default.
- W2617372202 hasConceptScore W2617372202C164705383 @default.
- W2617372202 hasConceptScore W2617372202C207001950 @default.
- W2617372202 hasConceptScore W2617372202C2777798775 @default.
- W2617372202 hasConceptScore W2617372202C2780559512 @default.
- W2617372202 hasConceptScore W2617372202C33923547 @default.
- W2617372202 hasConceptScore W2617372202C500558357 @default.
- W2617372202 hasConceptScore W2617372202C71924100 @default.
- W2617372202 hasConceptScore W2617372202C86803240 @default.
- W2617372202 hasLocation W26173722021 @default.
- W2617372202 hasOpenAccess W2617372202 @default.
- W2617372202 hasPrimaryLocation W26173722021 @default.
- W2617372202 hasRelatedWork W1991976410 @default.
- W2617372202 hasRelatedWork W2015763030 @default.
- W2617372202 hasRelatedWork W2026996320 @default.
- W2617372202 hasRelatedWork W2061247672 @default.
- W2617372202 hasRelatedWork W2093502227 @default.
- W2617372202 hasRelatedWork W2103442826 @default.
- W2617372202 hasRelatedWork W2380473145 @default.
- W2617372202 hasRelatedWork W2472038765 @default.
- W2617372202 hasRelatedWork W2885214115 @default.
- W2617372202 hasRelatedWork W2130232188 @default.
- W2617372202 isParatext "false" @default.
- W2617372202 isRetracted "false" @default.
- W2617372202 magId "2617372202" @default.
- W2617372202 workType "book-chapter" @default.