FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2617529895> ?p ?o ?g. }

• W2617529895 endingPage "362" @default.
• W2617529895 startingPage "354" @default.
• W2617529895 abstract "Atmospheric fine particulate matter (PM2.5) is a serious threat to human health. As a toxicant constituent, metal leads to significant health risks in a population, but exposure to PM2.5-bound metals and their biological impacts are not fully understood. In this study, we determined the metal contents of PM2.5 samples collected from a typical coal-burning city and then investigated the metabolic distributions of six metals (Zn, Pb, Mn, As, Cu, and Cd) following PM2.5 inhalation in mice in different developmental windows. The results indicate that fine particles were mainly deposited in the lung, but PM2.5-bound metals could reach and gather in secondary off-target tissues (the lung, liver, heart and brain) with a developmental window-dependent property. Furthermore, elevations in triglycerides and cholesterol levels in sensitive developmental windows (the young and elderly stages) occurred, and significant associations between metals (Pb, Mn, As and Cd) and cholesterol in the heart, brain, liver and lung were observed. These findings suggest that PM2.5 inhalation caused selective metal metabolic distribution in tissues with a developmental window-dependent property and that the effects were associated with lipid alterations. This provides a foundation for the underlying systemic toxicity following PM2.5 exposure based on metal components." @default.
• W2617529895 created "2017-06-05" @default.
• W2617529895 creator A5017312887 @default.
• W2617529895 creator A5038456429 @default.
• W2617529895 creator A5065236570 @default.
• W2617529895 creator A5070677473 @default.
• W2617529895 creator A5076642048 @default.
• W2617529895 date "2017-09-01" @default.
• W2617529895 modified "2023-10-15" @default.
• W2617529895 title "PM2.5-bound metal metabolic distribution and coupled lipid abnormality at different developmental windows" @default.
• W2617529895 cites W1886937137 @default.
• W2617529895 cites W1965030183 @default.
• W2617529895 cites W1969775324 @default.
• W2617529895 cites W1973956643 @default.
• W2617529895 cites W1977185107 @default.
• W2617529895 cites W1980806691 @default.
• W2617529895 cites W1981076200 @default.
• W2617529895 cites W1981516704 @default.
• W2617529895 cites W1982752849 @default.
• W2617529895 cites W1993099756 @default.
• W2617529895 cites W2001422326 @default.
• W2617529895 cites W2002389528 @default.
• W2617529895 cites W2003003259 @default.
• W2617529895 cites W2016569269 @default.
• W2617529895 cites W2019556304 @default.
• W2617529895 cites W2020019202 @default.
• W2617529895 cites W2020594846 @default.
• W2617529895 cites W2023085145 @default.
• W2617529895 cites W2023226705 @default.
• W2617529895 cites W2025849267 @default.
• W2617529895 cites W2030734532 @default.
• W2617529895 cites W2031038502 @default.
• W2617529895 cites W2035779341 @default.
• W2617529895 cites W2050694751 @default.
• W2617529895 cites W2054811645 @default.
• W2617529895 cites W2058036262 @default.
• W2617529895 cites W2059271594 @default.
• W2617529895 cites W2062609453 @default.
• W2617529895 cites W2063147179 @default.
• W2617529895 cites W2068149475 @default.
• W2617529895 cites W2069555799 @default.
• W2617529895 cites W2076682588 @default.
• W2617529895 cites W2081781496 @default.
• W2617529895 cites W2082221119 @default.
• W2617529895 cites W2087272914 @default.
• W2617529895 cites W2087607022 @default.
• W2617529895 cites W2090985202 @default.
• W2617529895 cites W2100634517 @default.
• W2617529895 cites W2105723376 @default.
• W2617529895 cites W2107719188 @default.
• W2617529895 cites W2110052313 @default.
• W2617529895 cites W2110232547 @default.
• W2617529895 cites W2111544271 @default.
• W2617529895 cites W2115063820 @default.
• W2617529895 cites W2116687544 @default.
• W2617529895 cites W2120199739 @default.
• W2617529895 cites W2128053929 @default.
• W2617529895 cites W2143416920 @default.
• W2617529895 cites W2150693059 @default.
• W2617529895 cites W2150751323 @default.
• W2617529895 cites W2152148584 @default.
• W2617529895 cites W2159899308 @default.
• W2617529895 cites W2164435812 @default.
• W2617529895 cites W2170697455 @default.
• W2617529895 cites W2222427237 @default.
• W2617529895 cites W2312086091 @default.
• W2617529895 cites W2410466020 @default.
• W2617529895 cites W2468758808 @default.
• W2617529895 cites W2492282451 @default.
• W2617529895 cites W250715704 @default.
• W2617529895 cites W2521186324 @default.
• W2617529895 cites W2527490055 @default.
• W2617529895 cites W2530195236 @default.
• W2617529895 doi "https://doi.org/10.1016/j.envpol.2017.05.040" @default.
• W2617529895 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28551565" @default.
• W2617529895 hasPublicationYear "2017" @default.
• W2617529895 type Work @default.
• W2617529895 sameAs 2617529895 @default.
• W2617529895 citedByCount "35" @default.
• W2617529895 countsByYear W26175298952018 @default.
• W2617529895 countsByYear W26175298952019 @default.
• W2617529895 countsByYear W26175298952020 @default.
• W2617529895 countsByYear W26175298952021 @default.
• W2617529895 countsByYear W26175298952022 @default.
• W2617529895 countsByYear W26175298952023 @default.
• W2617529895 crossrefType "journal-article" @default.
• W2617529895 hasAuthorship W2617529895A5017312887 @default.
• W2617529895 hasAuthorship W2617529895A5038456429 @default.
• W2617529895 hasAuthorship W2617529895A5065236570 @default.
• W2617529895 hasAuthorship W2617529895A5070677473 @default.
• W2617529895 hasAuthorship W2617529895A5076642048 @default.
• W2617529895 hasBestOaLocation W26175298951 @default.
• W2617529895 hasConcept C105702510 @default.
• W2617529895 hasConcept C107872376 @default.
• W2617529895 hasConcept C126322002 @default.
• W2617529895 hasConcept C134018914 @default.
• W2617529895 hasConcept C178790620 @default.
• W2617529895 hasConcept C185592680 @default.

• next